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Nutrition: Carbohydrates
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Total 3640 results found since Jan 2013.
Charting the solid-state NMR signals of polysaccharides: A database-driven roadmap
Magn Reson Chem. 2023 Sep 19. doi: 10.1002/mrc.5397. Online ahead of print.ABSTRACTSolid-state nuclear magnetic resonance (ssNMR) measurements of intact cell walls and cellular samples often generate spectra that are difficult to interpret due to the presence of many coexisting glycans and the structural polymorphism observed in native conditions. To overcome this analytical challenge, we present a statistical approach for analyzing carbohydrate signals using high-resolution ssNMR data indexed in a carbohydrate database. We generate simulated spectra to demonstrate the chemical shift dispersion and compare this with experi...
Source: Magnetic Resonance in Chemistry : MRC - September 19, 2023 Category: Chemistry Authors: Wancheng Zhao Debkumar Debnath Isha Gautam Liyanage D Fernando Tuo Wang Source Type: research
Transcriptome analysis of a springtail, Folsomia candida, reveals energy constraint and oxidative stress during petroleum hydrocarbon exposure
In this study, the effects of PHCs on conventional endpoints (i.e., survival and reproduction) and gene expression rates of a model springtail species, Folsomia candida were investigated. Age-synchronized F. candida were exposed to ecologically-relevant concentrations of soils spiked with fresh crude oil to calculate the reproductive EC25 and EC50 values using conventional toxicity testing. Soils spiked to these concentrations were then used to evaluate effects on the F. candida transcriptome over a 7-day exposure period. RNA-seq analysis found 98 and 132 differentially expressed genes when compared to the control for the ...
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Adrian Pang Allison Rutter Elizabeth Haack Barbara Zeeb Source Type: research
In-depth profiling of carbohydrate isomers in biological tissues by chemical derivatization-assisted mass spectrometry imaging
In this study, we propose a high-sensitive and isomer-specific imaging approach to visualize the spatial distributions of monosaccharide and disaccharide isomers by integrating chemical derivatization and matrix-assisted laser desorption/ionization tandem mass spectrometry imaging (MALDI-MS2I). 2-Pyridinecarbohydrazide (PYD) is developed as a novel derivatization reagent which can not only improves the MS sensitivity of carbohydrates, but also enables the identification and visualization of ketose and aldose monosaccharide isomers, as well as linkage pattern, monosaccharide composition and anomeric configuration disacchari...
Source: Analytica Chimica Acta - September 14, 2023 Category: Chemistry Authors: Lei Wang Yuhao Han Yaqi Zhang Haoyuan Geng Zihan Zhu Panpan Chen Xiaoqing Cui Xiao Wang Chenglong Sun Source Type: research
Protecting-group free synthesis of glycoconjugates displaying dual fungicidal and plant defense-eliciting activities
Bioorg Chem. 2023 Sep 3;141:106829. doi: 10.1016/j.bioorg.2023.106829. Online ahead of print.ABSTRACTA straightforward synthesis of carbohydrate templated isoxazolidines is described, by reaction of unprotected glycosylhydroxylamines (operating as 1,3-dipoles) with methyl acrylate using microwave activation. Rhamno- and erythro-isoxazolidines are recognized by plant cells, resulting in a strong ROS-production as a plant immune response, and exert a high antifungal activity against Botrytis cinerea.PMID:37690319 | DOI:10.1016/j.bioorg.2023.106829
Source: Bioorganic Chemistry - September 10, 2023 Category: Chemistry Authors: Nathan No ël Simon Duchateau Gatien Messire Fabien Massicot Jean-Luc Vasse Sandra Villaume Aziz Aziz St éphan Dorey J érôme Crouzet Jean-Bernard Behr Source Type: research
Carbohydrate antigen 125 in atrial fibrillation
This article reviews the role of CA-125 in patients with atrial fibrillation.PMID:37683718 | DOI:10.1016/j.cca.2023.117550
Source: International Journal of Clinical Chemistry - September 8, 2023 Category: Chemistry Authors: Rangrang Zhang Weidong Jin Minglei Han Yonglan Hou Source Type: research
Design of Glycopolymers for Controlling the Interactions with Lectins
Chem Asian J. 2023 Aug 25:e202300643. doi: 10.1002/asia.202300643. Online ahead of print.ABSTRACTCarbohydrates are involved in life activities through the interactions with their corresponding proteins (lectins). Pathogen infection and the regulation of cell activity are controlled by the binding between lectins and glycoconjugates on cell surfaces. A deeper understanding of the interactions of glycoconjugates has led to the development of therapeutic and preventive methods for infectious diseases. Glycopolymer is one of the classes of the materials present multiple carbohydrates. The properties of glycopolymers can be tun...
Source: Chemistry, an Asian Journal - August 25, 2023 Category: Chemistry Authors: Masanori Nagao Hikaru Matsumoto Yoshiko Miura Source Type: research
