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Drug dispensation at both community and hospital pharmacy the highly active antiretrovirals example
CONCLUSION: This study presents a complete inventory of the dual delivery system for antiretroviral therapies. Hospital and community therefore remain complementary to welcome outptients who will seek different delivery methods there. Little known to patients and professionals, this dual delivery system generates complexities at the stages of prescription, dispensing and reimbursement. It only concerns a minority of patients and its benefit for health insurance seems uncertain.PMID:37567558 | DOI:10.1016/j.pharma.2023.08.001
Source: Annales Pharmaceutiques Francaises - August 11, 2023 Category: Drugs & Pharmacology Authors: Laure Tribaudeau Blandine Juillard-Condat Florence Taboulet Fr éderic Eyvrard Source Type: research

Suboptimal Outcomes and Retreatment Rate of Crohn's Disease Patients after Forced Discontinuation of Biologics: A Nationwide Population-Based Study
This study investigated the retreatment rate and suboptimal outcomes [i.e., Crohn's disease-related surgeries, hospitalisations, emergency room visits and oral steroid flare-ups] after forced discontinuation. This retrospective cohort study was conducted using data from the National Health Insurance Database. Patients who received ≥40 weeks of biologic treatment followed by a forced discontinuation were included. The time of biologic retreatment and the cumulative incidence of suboptimal outcomes after the forced discontinuation as well as related risk factors were analyzed. 215 patients were included [68% male]. At the ...
Source: Clinical Pharmacology and Therapeutics - July 18, 2023 Category: Drugs & Pharmacology Authors: Nai-Yu Chen Chiao-Hsiung Chuang Yu-Ching Chang Yea-Huei Kao Yang Peng-Hsu Chen Ching-Lan Cheng Source Type: research

Utilization of Big Data with a Focus on Administrative Claims Database
Yakugaku Zasshi. 2023;143(6):497-500. doi: 10.1248/yakushi.22-00179-3.ABSTRACTWith the development of information technology, patient information is stored as electronic data, and huge amounts of such data are collected every day. Such a collection compiled over the course of clinical practice is called real-world data and is expected to be used for evaluating drug efficacy and safety. Real-world data such as health insurance association-based administrative claims databases, pharmacy-based dispensing databases, and spontaneous reporting system databases are mainly used in pharmaceutical research. Among them, claims databa...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - May 31, 2023 Category: Drugs & Pharmacology Authors: Satoshi Yokoyama Kouichi Hosomi Source Type: research

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