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Total 73 results found since Jan 2013.
Management from Primary Care of monkeypox infection (MPOX) in humans
Aten Primaria. 2023 Jun 19;55(10):102680. doi: 10.1016/j.aprim.2023.102680. Online ahead of print.ABSTRACTMonkeypox (MPOX) is a viral zoonosis endemic in West or Central African countries that is sporadically exported to another area. In May 2022, a global outbreak of MPOX smallpox began to occur in several countries in Europe and North America. Most of the reported cases are identified at the outpatient level and mainly affect men who have sex with men (MSM). Transmission is by close contact with lesions, body fluids, respiratory secretions or contaminated material from an infected person or animal. The clinical picture i...
Source: Atencion Primaria - June 21, 2023 Category: Primary Care Authors: Javier Arranz Izquierdo Jos é María Molero García Mar ía Isabel Gutiérrez Pérez Source Type: research
The battle against malaria in Africa has stalled. Can research in Mozambique explain why?
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Moisés Mapanga, a burly man of 49, is the bait. At 6 p.m. on a mid-April evening, he climbs into an orange tent outside his one-room house in Matutuíne, a hot, swampy district near Maputo, the cap...
Source: Science of Aging Knowledge Environment - September 8, 2022 Category: Geriatrics Source Type: research
The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
August 04, 2022 Edition-----The war seems to grind on sadly and Pres. Biden is having a second round with COVID as unprecedented weather happens all over the US. It all feels rather like ‘the end of days’!In the UK we see an increasing chance of a third female PM being elected as the country seems to be struggling. We do need to remember however the UK remains a significant power with nuclear weapons and home-grown nuclear submarines!In OZ we have had last week working out how to progress the First Nations ‘Voice’ as we wrap up the 1st session of Parliament for the new Government. Comments welcome on how you think ...
Source: Australian Health Information Technology - August 4, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Commentary: Experimental Mouse Models of Invasive Candidiasis Caused by < em > Candida auris < /em > and Other Medically Important < em > Candida < /em > Species
This study also establishes an inbred A/J mouse model of systemic C. auris infection without drug-induced immunosuppression. C. auris has become the first fungal pathogen causing global public health threat due to its multidrug resistance (MDR) and persistence in hospital and nursing home settings. Currently, as compared to C. albicans, very limited animal models are available to study the progression of non-albicans Candida (NAC) species including C. auris. We have successfully established immunosuppressed C57BL/6, BALB/c and A/J murine models of disseminated candidiasis caused by five clinically significant Candida speci...
Source: Cellular Immunology - July 18, 2022 Category: Allergy & Immunology Authors: Hong Xin Source Type: research
Therapeutic potential of highly diluted antibodies in antibiotic-resistant infection
Eur J Pharm Sci. 2022 Mar 3:106161. doi: 10.1016/j.ejps.2022.106161. Online ahead of print.ABSTRACTKlebsiella pneumoniae is one of the main causes of hospital-acquired infections. Its rate of antimicrobial resistance is rapidly increasing, while there are no licensed human vaccines against it. A novel therapeutic approach involves modulation of the host immune response combined with antibiotic treatment. One of the approaches to immunomodulation can be the use of antibodies (Abs) in a specific technological form of high dilutions (hd). The aim of the study was to assess whether hd-Abs could affect the antibacterial activit...
Source: European Journal of Pharmaceutical Sciences - March 6, 2022 Category: Drugs & Pharmacology Authors: Alexandra G Emelianova Natalia V Petrova Christophe Fremez Maxime Fontani é Sergey А Tarasov Оleg I Epstein Source Type: research
Middle East Respiratory Syndrome Coronavirus
Semin Respir Crit Care Med. 2021 Dec;42(6):828-838. doi: 10.1055/s-0041-1733804. Epub 2021 Dec 16.ABSTRACTThe past two decades have witnessed the emergence of three zoonotic coronaviruses which have jumped species to cause lethal disease in humans: severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1), Middle East respiratory syndrome coronavirus (MERS-CoV), and SARS-CoV-2. MERS-CoV emerged in Saudi Arabia in 2012 and the origins of MERS-CoV are not fully understood. Genomic analysis indicates it originated in bats and transmitted to camels. Human-to-human transmission occurs in varying frequency, being highest in h...
Source: Respiratory Care - December 17, 2021 Category: Respiratory Medicine Authors: Jaffar A Al-Tawfiq Esam I Azhar Ziad A Memish Alimuddin Zumla Source Type: research
