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Specialty: Neurosurgery
Therapy: Radiation Therapy

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Total 317 results found since Jan 2013.

Association between immunohistochemical markers and tumor progression following resection of spinal chordomas: a multicenter study
CONCLUSIONS: These IHC variables with tree-based machine learning tools successfully demonstrate a high capacity to identify a patient's tumor progression pattern with an accuracy of 66%. Pancytokeratin, EMA, cytokeratin A1/A3, and S100 protein were the IHC drivers of a low tumor progression. This shows the power of machine learning algorithms in analyzing and predicting outcomes of rare conditions in a small sample size.PMID:37728388 | DOI:10.3171/2023.6.SPINE23348
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Abdul Karim Ghaith Oluwaseun O Akinduro Carlos Perez-Vega Antonio Bon Nieves Kingsley Abode-Iyamah Naresh Patel Maziyar Kalani Michelle J Clarke Peter Rose Mohamad Bydon Source Type: research

Immunohistochemical markers predicting long-term recurrence following clival and spinal chordoma resection: a multicenter study
CONCLUSIONS: The IHC and clinicopathological variables combined with tree-based ML tools successfully demonstrated a high capacity to identify recurrence patterns with an accuracy of 77%. S100, pan-cytokeratin, and EMA were the IHC drivers of recurrence. This shows the power of ML algorithms in analyzing and predicting outcomes of rare conditions of a small sample size.PMID:37552641 | DOI:10.3171/2023.3.FOCUS22653
Source: Neurosurgical Focus - August 8, 2023 Category: Neurosurgery Authors: Abdul Karim Ghaith Oluwaseun O Akinduro A Yohan Alexander Anshit Goyal Antonio Bon-Nieves Leonardo de Macedo Filho Andrea Otamendi-Lopez Karim Rizwan Nathani Kingsley Abode-Iyamah Mark E Jentoft Bernard R Bendok Michelle J Clarke Michael J Link Jamie J Va Source Type: research