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Total 96 results found since Jan 2013.
pH-Responsive Zinc Ion Regulating Immunomodulatory Nanoparticles for Effective Cancer Immunotherapy
Biomacromolecules. 2023 Aug 24. doi: 10.1021/acs.biomac.3c00557. Online ahead of print.ABSTRACTHerein, we introduce a novel approach involving the utilization of a human serum albumin-coated zeolite imidazolate framework-8 containing a photosensitizer (HPZ) that exhibits targeted recognition of the tumor microenvironment, enabling the rapid elevation of zinc ion concentrations while facilitating the controlled release of an encapsulated photosensitizer (PS). At a physiological pH of 7.4, HPZ demonstrates a size of approximately 170 nm, significantly decreasing to less than 10 nm under pH 6.5 acidic conditions. Acid-induced...
Source: Biomacromolecules - August 24, 2023 Category: Biochemistry Authors: Byoungjun Lim Kyoung Sub Kim Kun Na Source Type: research
Obesity and lung cancer-a narrative review
CONCLUSIONS: The obesity paradox may arise due to the improper use of BMI as a measure of body composition. Measures of central obesity better portray the deleterious effects of obesity and are more appropriate to be discussed when talking about lung cancer. The use of obesity metrics based on anthropometric measurements and imaging modalities has been shown to be feasible and practical. However, a lack of standardization makes it difficult to interpret the results of studies using these metrics. Further research must be done to understand the association between these obesity metrics and lung cancer.PMID:37324095 | PMC:PM...
Source: Journal of Thoracic Disease - June 16, 2023 Category: Respiratory Medicine Authors: Yeshwanth Vedire Sukumar Kalvapudi Sai Yendamuri Source Type: research
