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Prognostic Value of Pressure-Volume Measures in Hemocompatibility-Related Clinical Adverse Events
Continuous-flow left ventricular assist device (cf-LVADs) can lead to hemocompatibility-related clinical adverse events (HRAEs) which are largely determined by mechanisms that underpin the pump-patient interaction. We assessed the association of pressure-volume (PV) measures [stroke work (SW)& pump arterial elastance (EA)] with incidence of HRAEs.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: A. Gunawan, D. Robson, A. Ramanayake, R.J. Krishnaswamy, K. Kearney, K. Muthiah, P. Jain, A. Adji, C.S. Hayward Tags: (220) Source Type: research

Stroke Risk in the Contemporary Era of Left Ventricular Assist Device Support
The HeartMate 3 left ventricular assist device (LVAD) has lower stroke rates compared to the HeartMate 2 in a clinical trial setting. Here we report real world stroke rates in patients implanted with HeartMate 2 and HeartMate 3 LVADs.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: J. Leonard, A. Shaaban, A.C. Agdamag, Z. Jedeon, R. John, F. Kamdar, V. Maharaj, R. Cogswell Tags: (119) Source Type: research

Protein Biomarkers Predict Risk of Gastrointestinal Bleeding in Left Ventricular Assist Device Patients
This study aims to assess the validity of these biomarkers in predicting the incidence of stroke or GIB in LVAD recipients.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: K. Cavallo, M. Kanwar, G. Diao, S.S. Sinha, R. Singh, D. Tang, I. Isseh, J. Brocious, P. Bagchi, D. Crandall, D.J. Farrar, S. Murali, J. Walenga, J. Lindenfeld, C. deFilippi, P. Shah Tags: (115) Source Type: research

Association of Outflow Cannula Angulation with Adverse Neurological Events in Patients with CF-LVAD
Adverse neurological outcomes are the Achilles heel of the current day LVAD technology and are associated with worse survival. Our previous data suggests that outflow cannula (OFC) angles measured using cardiac CT may correlate with stroke in continuous-flow HeartMate II patients. Therefore, the aim of our study was to assess the relationship of inflow cannula (IFC) and outflow cannula (OFC) position with neurological outcomes centrifugal flow pumps (HM3 and HVAD).
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: M. Kassi, S. Ingram, T. Garg, M. Chavez, M. Khan, A. Shah, R. Thaker, E. Graviss, N. Duc, A. Guha, E. Suarez, A. Bhimaraj Tags: (53) Source Type: research

Reservoir Pressure Analysis in Group 2 Pulmonary Hypertension
In this study we aim to describe Pres in Group 2 isolated post-capillary (IPC) and combined pre and post-capillary (CPC) pulmonary hypertension (PH).
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: I. Yim, K. Parker, S. Lim Tags: (307) Source Type: research

Bacteriophage Therapy and the Biofilm: An Old Solution for a Persistent and Desperate Problem?
With the adoption of use of continuous-flow pumps with centrifugal design and complete magnetic levitation (i.e., HeartMate 3, Abbott, Chicago, IL), outcomes following durable left ventricular assist device (LVAD) have continuously improved over the last five years (1). Improved hemocompatibility associated with this device design has translated into a significant reduction in major adverse events, primarily pump thrombosis, stroke, and to a lesser extent, reduction in non-surgical bleeding (1).
Source: The Journal of Heart and Lung Transplantation - February 14, 2022 Category: Transplant Surgery Authors: Pierre-Emmanuel Noly, Francis D. Pagani Tags: Editorial Source Type: research

Comparison of household income in in-hospital outcomes after implantation of left ventricular assist device
CONCLUSION: In patients undergoing LVAD implantation nationwide, low-income was associated with increased comorbidity burden, younger age, and fewer in-hospital complications and all-cause mortality.PMID:34719291 | DOI:10.1177/03913988211056960
Source: The International Journal of Artificial Organs - November 1, 2021 Category: Transplant Surgery Authors: Bertrand Ebner Morgan Karetnick Jelani Grant Louis Vincent Jennifer Maning Neal Olarte Odunayo Olorunfemi Colombo Rosario Sandra Chaparro Source Type: research

Impact of mechanical circulatory support on post-transplant stroke risk
This study assesses if the type of circulatory support device affects stroke risk in this population. The study cohort of 4257 adult patients bridged with mechanical support to cardiac transplant were derived from the UNOS transplant registry data. Risk factors assessed were age, gender, ischemic time, diabetes (recipient), durable mechanical support at listing and mechanical ventilation pre-transplant. Descriptive statistics were used to describe characteristics of the study cohort. Univariate logistic regression was used to test if there is a significant association between stroke event and all the potential risk factors...
Source: The International Journal of Artificial Organs - August 19, 2021 Category: Transplant Surgery Authors: Nandini Nair Shengping Yang Enrique Gongora Source Type: research

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