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Lower Baseline LDL Cholesterol Affects All-cause Mortality in Patients with First Percutaneous Coronary Intervention
CONCLUSION: In this study, a high baseline LDL-C was not associated with a low risk of clinical outcomes in CAD patients undergoing first PCI, which suggested that the "cholesterol paradox" may be inapplicable to Chinese populations.PMID:37105907 | DOI:10.3967/bes2023.038
Source: Biomedical and Environmental Sciences : BES - April 27, 2023 Category: Biomedical Science Authors: Xi Chen Hao Chen Bo Lu Wei Min Zhang Yuan Tao Qing Cheng Wang Guo Sheng Fu Wen Bin Zhang Source Type: research

Comparison of short-term clinical outcomes between low-dose prasugrel and clopidogrel as part of triple antithrombotic therapy in patients requiring oral anticoagulant therapy and percutaneous coronary intervention
ConclusionsCombination of low-dose prasugrel and DOAC was associated with lower incidence of MI, ischemic stroke, and blood transfusion. Low-dose prasugrel may be feasible as part of triple therapy in patients undergoing PCI.
Source: PLoS One - July 28, 2022 Category: Biomedical Science Authors: Hideki Kitahara Source Type: research

Prognostic significance of severe coronary microvascular dysfunction post-PCI in patients with STEMI: A systematic review and meta-analysis
by Marjorie Canu, Charles Khouri, St éphanie Marliere, Estelle Vautrin, Nicolas Piliero, Olivier Ormezzano, Bernard Bertrand, Hélène Bouvaist, Laurent Riou, Loic Djaileb, Clémence Charlon, Gerald Vanzetto, Matthieu Roustit, Gilles Barone-Rochette Coronary microvascular dysfunction (CMVD) is common and associated with poorer outcomes in patients with ST Segment Elevation Myocardial Infarction (STEMI). The index of microcirculatory resistance (IMR) and the index of hyperemic microvascular resistance (HMR) are both invasive indexes of microva scular resistance proposed for the diagnosis of severe CMVD after primary percu...
Source: PLoS One - May 16, 2022 Category: Biomedical Science Authors: Marjorie Canu Source Type: research

Clinical Outcomes of Ticagrelor in Korean Patients with Acute Myocardial Infarction without High Bleeding Risk
CONCLUSIONS: The bleeding risk of ticagrelor was attenuated in Korean patients with AMI without HBR. Appropriate patient selection could reduce in-hospital bleeding complications associated with ticagrelor in Korean patients with AMI who underwent successful PCI.PMID:34725976 | DOI:10.3346/jkms.2021.36.e268
Source: Journal of Korean Medical Science - November 2, 2021 Category: Biomedical Science Authors: Keun-Ho Park Myung Ho Jeong Hyun Kuk Kim Young-Jae Ki Sung Soo Kim Dong-Hyun Choi Young-Youp Koh Youngkeun Ahn Hyo-Soo Kim Hyeon-Cheol Gwon Seung-Woon Rha Jin-Yong Hwang KAMIR-NIH registry investigators Source Type: research

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