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Utility of a smartphone application in assessing palmar circulation prior to radial artery harvesting for coronary artery bypass grafting: rationale and design of the randomised CAPITAL iRADIAL-CABG trial
Introduction There is emerging evidence supporting the use of the radial artery (RA) as a preferred secondary conduit for coronary artery bypass grafting (CABG) as it is associated with higher rates of graft patency at 5 years when compared with saphenous vein grafts (SVG). The modified Allen’s test (MAT) is traditionally regarded as the standard of care in the assessment of ulnar artery (UA) patency prior to RA harvesting. Unfortunately, due to high false-positive rates, a substantial number of pre-CABG patients are found to have an abnormal MAT despite normal UA patency, resulting in inappropriate exclusion from RA...
Source: BMJ Open - April 8, 2022 Category: General Medicine Authors: Goh, C. Y., Parlow, S., Di Santo, P., Simard, T., Jung, R., Ahmed, Z., Verreault-Julien, L., Kuhar, P., Chan, V., Al-Atassi, T., Toeg, H., Bernick, J., Wells, G. A., Ruel, M., Hibbert, B. Tags: Open access, Cardiovascular medicine Source Type: research

A h áromér-betegség kezelése a FAME-3 vizsgálat eredményeinek tükrében
Orv Hetil. 2022 Jun 26;163(26):1032-1036. doi: 10.1556/650.2022.32487. Print 2022 Jun 26.ABSTRACTPrevious randomized clinical studies have shown the superiority of coronary artery bypass grafting over percutaneous coronary intervention in the treatment of severe multivessel disease mainly because of a reduced need for repeat revascularization but, in some, a mortality benefit and reduced rate of myocardial infarction were shown among those undergoing surgery. The late breaker multicentric, randomized FAME (Fractional Flow Reserve Versus Angiography in Multivessel Evaluation)-3 study, involving 1500 patients, sought to dete...
Source: Orvosi Hetilap - July 27, 2022 Category: General Medicine Authors: Zsolt Pir óth G ábor Fülöp Bettina Csan ádi G éza Fontos P éter Andréka No émi Nyolczas Jen ő Szolnoky Source Type: research

Antiplatelet agents and anticoagulants for hypertension
CONCLUSIONS: There is no evidence that antiplatelet therapy modifies mortality in patients with elevated BP for primary prevention. ASA reduced the risk of cardiovascular events and increased the risk of major bleeding events. Antiplatelet therapy with ASA probably reduces the risk of non-fatal and all cardiovascular events when compared to clopidogrel. Clopidogrel increases the risk of major bleeding events compared to ASA in patients with elevated BP for secondary prevention. There is no evidence that warfarin modifies mortality in patients with elevated BP for secondary prevention. The benefits and harms of the newer dr...
Source: Cochrane Database of Systematic Reviews - July 28, 2022 Category: General Medicine Authors: Eduard Shantsila Monika Kozie ł-Siołkowska Gregory Yh Lip Source Type: research

A h áromér-betegség kezelése a FAME-3 vizsgálat eredményeinek tükrében
Orv Hetil. 2022 Jun 26;163(26):1032-1036. doi: 10.1556/650.2022.32487. Print 2022 Jun 26.ABSTRACTPrevious randomized clinical studies have shown the superiority of coronary artery bypass grafting over percutaneous coronary intervention in the treatment of severe multivessel disease mainly because of a reduced need for repeat revascularization but, in some, a mortality benefit and reduced rate of myocardial infarction were shown among those undergoing surgery. The late breaker multicentric, randomized FAME (Fractional Flow Reserve Versus Angiography in Multivessel Evaluation)-3 study, involving 1500 patients, sought to dete...
Source: Orvosi Hetilap - July 27, 2022 Category: General Medicine Authors: Zsolt Pir óth G ábor Fülöp Bettina Csan ádi G éza Fontos P éter Andréka No émi Nyolczas Jen ő Szolnoky Source Type: research

Comparative efficacy of eight therapeutic methods in the treatment of left main coronary artery disease: a Bayesian network meta-analysis protocol
Introduction As for coronary artery bypass grafting, although there are many direct comparative studies on different minimally invasive methods and traditional thoracotomy (off-pump/on-pump), there is still a lack of further ranking and summary of the efficacy of all surgical methods for left main coronary artery (LMCA) lesions. Combined with the current controversial views, this study aims to introduce a planned network meta-analysis (NMA) in detail, with a view to comparing the long-term efficacy and safety of multiple therapeutic methods in the treatment of patients with LMCA disease, and finally providing some referenc...
Source: BMJ Open - September 6, 2022 Category: General Medicine Authors: Hou, B., Chen, M., Li, Q., Huang, W., Wang, L. Tags: Open access, Cardiovascular medicine Source Type: research

Coronary atherosclerotic burden assessed by SYNTAX scores and outcomes in surgical, percutaneous or medical strategies: a retrospective cohort study
Conclusions Coronary atherosclerotic burden alone was not associated with significantly increased risk of all-cause mortality. The SSII better discriminates the risk of death. Trial registration number ISRCTN66068876.
Source: BMJ Open - September 22, 2022 Category: General Medicine Authors: Scudeler, T. L., Farkouh, M. E., Hueb, W., Rezende, P. C., Campolina, A. G., Martins, E. B., Godoy, L. C., Soares, P. R., Ramires, J. A. F., Kalil Filho, R. Tags: Open access, Cardiovascular medicine Source Type: research

Revascularisation and outcomes after acute coronary syndromes in patients with prior coronary artery bypass grafting-ANZACS-QI 67
CONCLUSION: In contemporary real-world practice, despite half of the patients with ACS and prior CABG receiving PCI, the outcomes remain poor compared with those without prior CABG.PMID:36201732
Source: New Zealand Medical Journal - October 6, 2022 Category: General Medicine Authors: Danting Wei Jithendra B Somaratne Mildred Lee Andrew Kerr Source Type: research

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