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Management: National Institutes of Health (NIH)
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Total 165 results found since Jan 2013.
Intra‐arterial bone marrow mononuclear cells (BM‐MNCs) transplantation in acute ischemic stroke (IBIS trial): protocol of a phase II, randomized, dose‐finding, controlled multicenter trial
DiscussionThis is the first trial to explore efficacy of different doses of intra‐arterial bone marrow mononuclear cell in moderate‐to‐severe acute ischemic stroke patients. The trial is registered as NCT02178657.
Source: International Journal of Stroke - June 4, 2015 Category: Neurology Authors: Francisco Moniche, Irene Escudero, Elena Zapata‐Arriaza, María Usero‐Ruiz, María Prieto‐León, Javier Torre, Miguel‐Angel Gamero, Jose Antonio Tamayo, Juan‐José Ochoa‐Sepúlveda, José Maestre, Magdalena Carmona, Pilar Piñero, Cristina Cal Tags: Protocol Source Type: research
Intrathecal Injection of Allogenic Bone Marrow-Derived Mesenchymal Stromal Cells in Treatment of Patients with Severe Ischemic Stroke: Study Protocol for a Randomized Controlled Observer-Blinded Trial
AbstractMesenchymal stromal cells (MSCs) can differentiate into multiple tissues. Preclinical studies have shown that MSC-based therapy is a potential new treatment approach for ischemic stroke. These results support the urgent need for further studies of MSC transplantation in the treatment of ischemic stroke in humans. Here, we develop a prospective, randomized, controlled, observer-blinded phase II trial to assess the clinical safety, feasibility, and therapeutic mechanisms of allogenic bone marrow-derived MSCs (BM-MSCs) by intrathecal infusion in the treatment of patients with cerebral infarction within the middle cere...
Source: Translational Stroke Research - May 23, 2018 Category: Neurology Source Type: research
Role of Renal Dysfunction as a Prognostic Factor in Acute Stroke Patients at a Tertiary Hospital in Northeastern Nigeria
Saudi J Kidney Dis Transpl. 2021 Jan-Feb;32(1):199-203. doi: 10.4103/1319-2442.318524.ABSTRACTChronic kidney disease (CKD) and stroke share many common risk factors, and the presence of CKD confers added risk factors for stroke. With increasing interest and understanding of the close relationship between the kidney and the brain, this study aims to assess the prevalence and impact of renal dysfunction on outcomes acute stroke patients. This is a prospective hospital-based study carried out in the neurology unit of University of Maiduguri Teaching Hospital, Maiduguri, northeastern Nigeria. The study population consisted of ...
Source: Saudi Journal of Kidney Diseases and Transplantation - June 19, 2021 Category: Urology & Nephrology Authors: Mohammad Maina Sulaiman Musa Mamman Watila Jummai Shettima Ibrahim Ummate Yakubu Wilberforce Nyandaiti Source Type: research
