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Can you learn to cough after having a stroke?
A strong cough, requires powerful coordinated contraction of expiratory (abdominal) muscles. The expiratory muscles contract to build up high positive intrapleural and intra-airway pressures for development of peak expiratory Flow rates. Expiratory muscle strength training (EMST) has been shown to improve parameters related to pulmonary function, speech, and cough.However, no one has investigated what changes occur in the activation of abdominal muscles after training. The aim of this study is to clarify which role plays the coordination of abdominal muscles in expiratory flows. The null hypothesis was that stroke patients...
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Dominguez Sanz, N. Tags: 09.02 - Physiotherapists Source Type: research

Medtech approvals: FDA releases August 2015 PMAs
The FDA today released its list of the pre-market approvals it granted for medical devices in August 2015: Summary of PMA Originals & Supplements Approved Originals: 2 Supplements: 70 Summary of PMA Originals Under Review Total Under Review: 57 Total Active: 28 Total On Hold: 29 Summary of PMA Supplements Under Review Total Under Review: 569 Total Active: 422 Total On Hold: 147 Summary of All PMA Submissions Originals: 5 Supplements: 90 Summary of PMA Supplement PMA Approval/Denial Decision Times Number of Approvals: 70 Number of Denials: 0 Average Days Fr Receipt to Decision (Total Time): 229.0 FDA Time: 130...
Source: Mass Device - October 23, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Pre-Market Approval (PMA) Regulatory/Compliance Source Type: news

NA Looks to Lead Robotics-Based Ultrasound Revolution
Neural Analytics is bringing robotics to the world of ultrasound through its NeuralBot system. The Los Angeles, CA-based company said it has both CE mark and FDA clearance for the technology, which is an ultrasound guidance device to observe blood flow to the brain. The firm said NeuralBot will be launched in both Europe and the U.S. throughout the course of next year. “We have identified a number of clinical partners and sites that are excited to be early adopters of the system,” Loe Petrossian, PhD and CEO of Neural Analytics, told MD+DI. Petrossian helped found the Neural Analytics in 2013. The private company has r...
Source: MDDI - June 19, 2018 Category: Medical Devices Authors: Omar Ford Tags: Business Source Type: news

Magnetic Nanobubble Mechanical Stress Induces the Piezo1 ‐Ca2+‐BMP2/Smad Pathway to Modulate Neural Stem Cell Fate and MRI/Ultrasound Dual Imaging Surveillance for Ischemic Stroke
Magnetic nanobubbles (MNBs) assembled from magnetic nanoparticles are fabricated. When interacting with neural stem cells (NSCs), these MNB nanostructures can contract and expand with volumetric oscillation, leading to a change in intramembrane mechanical properties. Therefore, MNBs can serve as acoustic sensors to transduce Piezo1-Ca2+- triggered BMP2/Smad signals regulating NSC development and can be tracked using magnetic resonance and ultrasound dual imaging. AbstractNeural stem cells (NSCs) are used to treat various nervous system diseases because of their self-renewal ability and multidirectional differentiation pote...
Source: Small - May 12, 2022 Category: Nanotechnology Authors: Jing Li, Yao Zhang, Zhichao Lou, Mingxi Li, Lin Cui, Zhenrong Yang, Lijuan Zhang, Yu Zhang, Ning Gu, Fang Yang Tags: Research Article Source Type: research