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Lipoprotein Apheresis: Current Recommendations for Treating Familial Hypercholesterolemia and Elevated Lipoprotein(a)
Curr Atheroscler Rep. 2023 Jun 5. doi: 10.1007/s11883-023-01113-2. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Familial hypercholesterolemia (FH) and hyperlipoproteinemia(a) are relatively common disorders, posing a significant health burden due to increased risk of atherosclerotic cardiovascular disease (ASCVD). Development of electronic health record-based strategies with a linkage to the genetic test results has increased awareness, detection, and control of heritable lipid disorders. This review attempts to critically examine available data to provide a summary of the current evidence for lipoprotein apheresis in ...
Source: Atherosclerosis - June 5, 2023 Category: Cardiology Authors: Maya S Safarova Patrick M Moriarty Source Type: research

Difference between arterial and end-tidal carbon dioxide and adverse events after non-cardiac surgery: a historical cohort study
CONCLUSIONS: In this patient population, increased intraoperative ΔCO2 was associated with an increased odds of the composite outcome of postoperative mechanical ventilation, re-intubation, or 30-day mortality that was independent of its relationship with pre-existing pulmonary disease. Future studies are needed to determine if ΔCO2 can be used to guide patient management and improve patient outcomes.PMID:34617239 | PMC:PMC8494171 | DOI:10.1007/s12630-021-02118-8
Source: Canadian Journal of Anaesthesia - October 7, 2021 Category: Anesthesiology Authors: Ryan Davis Elizabeth Jewell Milo Engoren Michael Maile Source Type: research

Risk factors and treatment of oxygenator high-pressure excursions during cardiopulmonary bypass
CONCLUSIONS: Large body surface area, high hematocrit during CPB, previous stroke and acute surgery were independently associated with HPE. A treatment protocol including epoprostenol appears to be a safe option. Perioperative stroke rate was increased in HPE patients.PMID:34510993 | DOI:10.1177/02676591211043700
Source: Perfusion - September 13, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Anders Karl Hj ärpe Anders Jeppsson Lukas Lannemyr Martin Lindgren Source Type: research