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Management and outcomes of surgical site tuberculosis infection due to infected bone graft in spine surgery: a single-institution experience and 1-year postoperative follow-up
CONCLUSIONS: Direct inoculation with TB via contaminated bone grafts resulted in a high rate of severe soft-tissue infection, although extensive skeletal and pulmonary involvement has not been observed at 1 year postoperatively; this review includes the longest reported follow-up period for this TB outbreak. Medical management remains the mainstay of therapy for these patients, with most patients showing recovery with oral antibiotic therapy. The severity of these infections arising from mesenchymal stem cell-containing bone allografts that undergo an alternative sterilization process than standard allografts raises concer...
Source: Journal of Neurosurgery.Spine - October 22, 2022 Category: Neurosurgery Authors: Luke G McVeigh Mohamed A Zaazoue Brandon C Lane Jason M Voorhies Jamie Bradbury Source Type: research

Posterior limited unilateral fenestration approach for treating patients with single-segment thoracic and lumbar tuberculosis
ConclusionsFor patients with single-segment thoracic and lumbar TB, PLUF debridement, bone grafting fusion, and instrumentation are a feasible and effective surgical treatment.
Source: Acta Neurochirurgica - September 7, 2022 Category: Neurosurgery Source Type: research

Temporary standalone percutaneous fixation with pedicle screws for the treatment of subacute tuberculous osteomyelitis with kyphotic deformity in the lumbar spine
CONCLUSION: Here, we present an exceedingly rare case of BCG vaccine-induced L1-2 spinal tuberculosis with extensive vertebral body destruction and deformity. This was effectively treated with standalone temporary pedicle fixation instead of corpectomy and reconstruction.PMID:35855170 | PMC:PMC9282791 | DOI:10.25259/SNI_457_2022
Source: Surgical Neurology International - July 20, 2022 Category: Neurosurgery Authors: Mokshal H Porwal Danyon J Anderson Omar Hussain Brandon Robert Winston Laing Hesham Soliman Source Type: research

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