• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Effect of a Family Pharmacist System on Medication Adherence of Patients with Dyslipidemia during a COVID-19 Epidemic
In this study, using anonymously processed receipt data from 700 insurance pharmacies in our group, we evaluated medication adherence in patients taking statin drugs before, during the first and second years of coronavirus disease 2019 (COVID-19) epidemic in terms of medication persistence and medication possession, and compared the results between the family pharmacist group (FP group) and non-family pharmacist group (NoFP group). The odds ratios of good medication adherence (medication persistence and medication possession) rates for the FP group relative to the NoFP group were 1.446 [95% confidence interval (CI): 1.210-...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - September 4, 2023 Category: Drugs & Pharmacology Authors: Mamoru Maeda Yoshitaka Hasegawa Ryota Tsukioka Miya Oishi Source Type: research

Modifications of Lipid Pathways Restrict SARS-CoV-2 Propagation in Human Induced Pluripotent Stem Cell-derived 3D Airway Organoids
CONCLUSIONS: Together, our data demonstrated that modifications of lipid pathways restrict SARS-CoV-2 propagation in the iPSC-AOs, which the inhibition is speculated through the translocation of ACE2 from the cell membrane to the cytosol. Considering the highly frequent mutation and generation of SARS-CoV-2 variants, targeting host metabolisms of cholesterol or other lipids may represent an alternative approach against SARS-CoV-2 infection.PMID:37557954 | DOI:10.1016/j.jare.2023.08.005
Source: Adv Data - August 9, 2023 Category: Epidemiology Authors: Ping-Hsing Tsai Jun-Ren Sun Yueh Chien Man Sheung Chan Winnie Khor Hsin-Chou Yang Chih-Heng Huang Chia-Ni Hsiung Teh-Yang Hwa Yi-Ying Lin Chih-Ling Yeh Mong-Lien Wang Yi-Ping Yang Yuh-Min Chen Fu-Ting Tsai Meng-Shiue Lee Yun-Hsiang Cheng Shan-Ko Tsai Ping Source Type: research

Challenges in Conducting Therapeutic Trials in Pregnancy: Emphasizing Recent Lessons Learned
This article reviews the history of research guidelines in pregnancy and illustrates ongoing challenges, as seen in the development of vaccines and therapies during the coronavirus disease 2019 pandemic and investigation of statins for preeclampsia prevention. It explores new approaches that may be used to improve therapeutic research in pregnancy. A major cultural shift is needed to balance potential maternal and/or fetal risks with potential benefits from participation in research, as well as harm from withholding treatment or providing one that is not evidence-based. Finally, it is important to honor maternal autonomy i...
Source: The Journal of Clinical Pharmacology - June 15, 2023 Category: Drugs & Pharmacology Authors: Tracy Caroline Bank Catherine S Stika Raman Venkataramanan Christine Field Maged M Costantine Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11  12