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The Impact of COVID19 on Treatment Practices for Patients With Early Breast Cancer: A Cross-Sectional Study From a Large Cancer Center In Italy
CONCLUSIONS: There was no evidence for major changes in the management of patients with EBC during 2019-2021 and no treatment delays were observed. Our findings suggest that more women presented with palpable nodules at diagnosis, but the stage distribution did not change over time. Validation on a larger cohort of patients is warranted to robustly assess the impact of the COVID19 pandemic on treatment practices for patients with EBC.PMID:37699107 | DOI:10.1093/oncolo/oyad255
Source: The Oncologist - September 12, 2023 Category: Cancer & Oncology Authors: Fabio Girardi Sabrina Marini Francesca Porra Sonia Carpentieri Alberto Marchet Tania Saibene Marcello Lo Mele Tommaso Giarratano Carlo Alberto Giorgi Eleonora Mioranza Cristina Falci Giovanni Faggioni Francesca Caumo Gaia Griguolo Maria Vittoria Dieci Val Source Type: research

Impact of COVID-19 on pancreatic cancer surgery: A high-volume Polish center experience
CONCLUSIONS: Particular attention should be paid to patients with an aggressive type of cancer who have completed neoadjuvant therapy, as they are unable to undergo other therapeutic options. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive cancer patients should be postponed until recovery. Relatively few postoperative complications and low all-cause mortality are the result of a more careful selection of oncological patients before the admission to the surgical ward, as well as a ompliance with the principles of planning the procedure and organization of the operating theater during the COVID-19 pand...
Source: Adv Data - February 2, 2022 Category: Epidemiology Authors: Karolina K ędzierska-Kapuza Grzegorz Witkowski Katarzyna Baumgart-Gryn Aleksandra Szyli ńska Marek Durlik Source Type: research

ASO Visual Abstract: Neoadjuvant Endocrine Therapy and Delays in Surgery for Ductal Carcinoma in Situ: Implications for the Coronavirus Pandemic
Ann Surg Oncol. 2021 Oct 26:1. doi: 10.1245/s10434-021-10973-4. Online ahead of print.NO ABSTRACTPMID:34704180 | PMC:PMC8547306 | DOI:10.1245/s10434-021-10973-4
Source: Ann Oncol - October 27, 2021 Category: Cancer & Oncology Authors: Austin D Williams Cecilia Chang Elin R Sigurdson Chihsiung Wang Allison A Aggon Maureen V Hill Andrea Porpiglia Richard J Bleicher Source Type: research

Neoadjuvant Endocrine Therapy and Delays in Surgery for Ductal Carcinoma in Situ: Implications for the Coronavirus Pandemic
CONCLUSIONS: This analysis of a pre-COVID cohort showed evidence for a protective effect of NET in HR+ DCIS against the development of invasive cancer as the preoperative delay increased, although an appropriately powered prospective trial is needed for a definitive answer.PMID:34635974 | PMC:PMC8504964 | DOI:10.1245/s10434-021-10883-5
Source: Ann Oncol - October 12, 2021 Category: Cancer & Oncology Authors: Austin D Williams Cecilia Chang Elin R Sigurdson Chih-Hsiung Wang Allison A Aggon Maureen V Hill Andrea Porpiglia Richard J Bleicher Source Type: research

Analysis of the Impact of the COVID-19 Pandemic on the Multidisciplinary Management of Breast Cancer: Review from the American Society of Breast Surgeons COVID-19 and Mastery Registries
CONCLUSION: The ASBrS COVID-19 registry provided a platform for monitoring treatment changes due to the pandemic, highlighting the increased use of NET.PMID:34431019 | DOI:10.1245/s10434-021-10639-1
Source: Ann Oncol - August 25, 2021 Category: Cancer & Oncology Authors: Lee G Wilke Toan Thien Nguyen Qiuyu Yang Bret M Hanlon Kathryn A Wagner Pamela Strickland Eric Brown Jill R Dietz Judy C Boughey Source Type: research

Surgical Management of Axilla Following Neoadjuvant Endocrine Therapy
CONCLUSIONS: Among biopsy-proven cN+ NET patients, we observed deescalation of axillary surgery in selected patients, despite a low nodal pathologic complete response (pCR) rate, without nodal recurrences. These data suggest that patients with low-volume axillary disease treated with NET may be managed similarly to patients treated with a surgery-first approach.PMID:34275042 | DOI:10.1245/s10434-021-10385-4
Source: Ann Oncol - July 18, 2021 Category: Cancer & Oncology Authors: Brenna M Murphy Tanya L Hoskin Amy C Degnim Judy C Boughey Tina J Hieken Source Type: research

Effectiveness of a Short Duration of Neoadjuvant Endocrine Therapy in Patients with HR+ Breast Cancer-An NCDB Analysis (2004-2016)
CONCLUSION: Short NET duration did not result in an inferior ORR. Future study to evaluate the interaction between surgery delay and NET use on clinical outcome will provide insights into the safety of NET to bridge potential surgery delay in patients with HR+ breast cancer.PMID:34125350 | DOI:10.1245/s10434-021-10287-5
Source: Ann Oncol - June 14, 2021 Category: Cancer & Oncology Authors: Macy M Goldbach Laura Burkbauer Tina Bharani Austin D Williams Luke Keele Jami Rothman Rachel Jankowitz Julia C Tchou Source Type: research

Neoadjuvant PD-1 inhibitors and chemotherapy for locally advanced NSCLC: A retrospective study
CONCLUSIONS: Induction ICI-chemotherapy may be a valid treatment in patients with locally advanced NSCLC, providing important tumor downstaging and rendering patients operable. In our experience patients had few side effects and a good pathological response.PMID:33781737 | DOI:10.1016/j.athoracsur.2021.03.041
Source: The Annals of Thoracic Surgery - March 30, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Tianxiang Chen Junwei Ning Alessio Campisi Andrea Dell'Amore Angelo Paolo Ciarrocchi Ziming Li Liwei Song Jia Huang Yunhai Yang Franco Stella Qingquan Luo Source Type: research