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Total 116 results found since Jan 2013.

Renal mitochondrial dysfunction in ovine experimental sepsis associated acute kidney injury
In conclusion, renal mitochondrial dysfunction comprised of a reduction of the RCR and an increased CII/CI-relation in State 3 was demonstrated in an ovine model of SA-AKI. However, the disturbed relation between renal VO2 and renal sodium transport could not be explained by a change in renal cortical mitochondrial efficiency or uncoupling.PMID:37102685 | DOI:10.1152/ajprenal.00294.2022
Source: Am J Physiol Renal P... - April 27, 2023 Category: Urology & Nephrology Authors: Tomas Luther Sara B ülow Anderberg Patrik Persson Stephanie Franz én Paul Skorup Annika Wernerson Kjell Hultenby Fredrik Palm Tomas A Schiffer Robert Frithiof Source Type: research

Dysbiosis and reduced small intestinal function are required to induce intestinal insufficiency in mice
Am J Physiol Gastrointest Liver Physiol. 2022 Nov 8. doi: 10.1152/ajpgi.00201.2022. Online ahead of print.ABSTRACTExtensive bowel resection can lead to short bowel syndrome and intestinal failure. Resection-induced dysbiosis may be related to the specific anatomic site of resection and influences the disease progression. While patients with end-jejunostomy are at high risk for intestinal failure, preservation of the ileocecal valve and colon counteracts this risk. The present study investigated the role of the cecum in maintaining microbial homeostasis after different types of small bowel resection. Male C57BL6/J mice were...
Source: Am J Physiol Gastroi... - November 8, 2022 Category: Gastroenterology Authors: Peggy Berlin Israel Barrantes Johannes Reiner Emma Schr öder Brigitte Vollmar Jana Bull Bernd Kreikemeyer Georg Lamprecht Maria Witte Source Type: research