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Infectious Disease: Epidemics

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Total 4946 results found since Jan 2013.

Strain and sex-related behavioral variability of oxycodone dependence in rats
In conclusion, this study identifies strain differences in the behavioral responses and pharmacokinetics associated with oxycodone self-administration in rats, providing a robust foundation for identifying genetic and molecular variants associated with various facets of the opioid addiction process.PMID:37327971 | DOI:10.1016/j.neuropharm.2023.109635
Source: Neuropharmacology - June 16, 2023 Category: Drugs & Pharmacology Authors: Michelle R Doyle Angelica R Martinez Ran Qiao Selen Dirik Francesca Di Ottavio Glenn Pascasio R émi Martin-Fardon Christopher Benner Olivier George Francesca Telese Giordano de Guglielmo Source Type: research

Improving Chronic Pain Management in a Family Medicine Residency
CONCLUSION: Provider comfort with CPM and OUD increased over the course of the intervention. We were also able to introduce MAT, adding a tool to the toolbox to help our residents and graduates treat OUD.PMID:37307391 | DOI:10.22454/FamMed.2023.499454
Source: Family Medicine - June 12, 2023 Category: Primary Care Authors: Matthew Traxler Jamie Borick Samuel Ofei-Dodoo Amy Curry Sarah Love Cynthia Nash Source Type: research

Post-Operative Opioid Consumption Following Hallux Valgus and Rigidus Surgery: A Guide to Post-Operative Prescription Writing
Prescribing post-operative pain medications is essential to foot and ankle surgery, however, prescribing an amount that results in an excess of pills has shown to lead to opioid abuse. The opioid epidemic has forced surgeons to analyze how we manage post-operative pain with a goal to prescribe the optimal number of pills that will reduce a patient's pain while limiting the amount that is left over. The purpose of this study was to develop a guideline for prescribing post-operative pain medication for hallux valgus and rigidus procedures.
Source: Journal of Foot and Ankle Surgery - June 12, 2023 Category: Orthopaedics Authors: Jake Eisenschink, Dennis Leveille, Rachelle Leveille, Anthony Mollica, Joshua Rhodenizer Tags: Original Research Source Type: research

Postoperative Opioid Consumption Following Hallux Valgus and Rigidus Surgery: A Guide to Postoperative Prescription Writing
Prescribing postoperative pain medications is essential to foot and ankle surgery; however, prescribing an amount that results in an excess of pills has shown to lead to opioid abuse. The opioid epidemic has forced surgeons to analyze how we manage postoperative pain with a goal to prescribe the optimal number of pills that will reduce a patient's pain while limiting the amount that is left over. The purpose of this study was to develop a guideline for prescribing postoperative pain medication for hallux valgus and rigidus procedures.
Source: Journal of Foot and Ankle Surgery - June 12, 2023 Category: Orthopaedics Authors: Jake Eisenschink, Dennis Leveille, Rachelle Leveille, Anthony Mollica, Joshua Rhodenizer Tags: Original Research Source Type: research

Opioid Stewardship in Urology: Quality Improvement Summit 2018
CONCLUSIONS: The 2018 AUA Quality Improvement Summit provided a platform for urologists to discuss the opioid epidemic and to learn strategies for combatting this issue from multidisciplinary experts. Physician led opioid stewardship and research, facilitated by this Summit, may enhance the quality and safety of medical care and improve the lives of patients, their families and their communities.PMID:37296566 | DOI:10.1097/UPJ.0000000000000113
Source: Pain Physician - June 10, 2023 Category: Anesthesiology Authors: Gregory Auffenberg Angela B Smith Timothy D Averch Richard J Barth Tudor Borza Chad Brummett Brooke Chidgey Benjamin Davies James M Dupree Behfar Ehdaie Matthew E Nielsen Vernon M Pais Margaret Rukstalis Meghan Sperandeo-Fruge Jonah Stulberg Jennifer F Wa Source Type: research

Unmasking the truth: the shocking reality of the opioid epidemic and who ’ s really to blame
An excerpt from Burden of Pain: A Physician’s Journey through the Opioid Epidemic. Glide your hand over a piece of velvet and you notice the smoothness. You feel its aggregated smoothness, not the individualized roughness of each fiber. Each fleeting fiber, a prick of truth, is nullified, synthesized, and then magnified into the silky fluency Read more… Unmasking the truth: the shocking reality of the opioid epidemic and who’s really to blame originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - June 7, 2023 Category: General Medicine Authors: Tags: Physician Pain Management Source Type: blogs

Cell-type specific molecular architecture for mu opioid receptor function in pain and addiction circuits
Neuropharmacology. 2023 Jun 2:109597. doi: 10.1016/j.neuropharm.2023.109597. Online ahead of print.ABSTRACTOpioids are potent analgesics broadly used for pain management; however, they can produce dangerous side effects including addiction and respiratory depression. These harmful effects have led to an epidemic of opioid abuse and overdose deaths, creating an urgent need for the development of both safer pain medications and treatments for opioid use disorders. Both the analgesic and addictive properties of opioids are mediated by the mu opioid receptor (MOR), making resolution of the cell types and neural circuits respon...
Source: Neuropharmacology - June 4, 2023 Category: Drugs & Pharmacology Authors: Nicole E Ochandarena Jesse Niehaus Adrien Tassou Gr égory Scherrer Source Type: research

Variations of pain medication use for patients with acute extremity pain in an emergency department: A quality improvement project
CONCLUSION: There are patient, prescriber, and environment-specific characteristics that are associated with analgesic selection in an ED. Combination therapy had the greatest reduction in pain regardless of the two medications received.PMID:37270423 | DOI:10.5055/jom.2023.0770
Source: Pain Physician - June 3, 2023 Category: Anesthesiology Authors: Rachael M Cardinal Frank D'Amico Elizabeth Cassidy Richard Heath Megan Baumgartner Source Type: research

New legislation in New Jersey reduced opioid use among trauma patients
CONCLUSION: Overall, opioid consumption was lower in 2018 without negatively affecting the quality of pain management. This suggests that the implementation of the new legislation has successfully reduced inpatient opioid use.PMID:37270420 | DOI:10.5055/jom.2023.0767
Source: Journal of Opioid Management - June 3, 2023 Category: Addiction Authors: Renay Durling-Grover Louis T DiFazio John M Adams Karen Kong Sara S Soliman Daniel Hakakian Keren Kaynan Rolando H Rolandelli Zoltan H Nemeth Source Type: research