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Source: American Journal of Translational Research
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Total 722 results found since Jan 2013.
FOXO1 regulates NLRP3 inflammasome proteins in LPS-induced cardiotoxicity
CONCLUSION: FOXO1 overexpression attenuated apoptosis, ROS generation, and inflammation, whereas FOXO1 inhibition aggravated LPS-induced cardiomyocyte injury via the NLRP3 inflammasome signaling pathway.PMID:37692952 | PMC:PMC10492091
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Hui Zhao Lingcun Qin Ruyi Wang Dejie Qu Suting Li Source Type: research
A pan-cancer analysis of pituitary tumor-transforming 3, pseudogene
CONCLUSION: Our pan-cancer based findings provided a comprehensive account of the oncogenic role and utilization of PTTG3P as a novel molecular biomarker of ESCA and HNSC.PMID:37692950 | PMC:PMC10492052
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Jie Li Saima Naz Shaikh Arsalan Ahmed Uqaili Hilal Nasir Rabeea Zia Muhammad Aitzaz Akram Fahim Ali Jawad Salman Sohail Mohamed Ragab AbdelGawwad Saeedah Musaed Almutairi Mohamed S Elshikh Muhammad Jamil Rabab Ahmed Rasheed Source Type: research
Raloxifene, a SERM targets PD-L1: an in-silico study
CONCLUSIONS: PD-L1 is a potential target of the SERM raloxifene in-silico. Overall, this study is one step further towards immune checkpoint blockade using small-molecule inhibitors.PMID:37692949 | PMC:PMC10492081
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Chirag Chopra Tenzen Yodun Harpreet Singh Bhupender Singh Shashank K Singh Umesh Goutam Source Type: research
FOXO1 regulates NLRP3 inflammasome proteins in LPS-induced cardiotoxicity
CONCLUSION: FOXO1 overexpression attenuated apoptosis, ROS generation, and inflammation, whereas FOXO1 inhibition aggravated LPS-induced cardiomyocyte injury via the NLRP3 inflammasome signaling pathway.PMID:37692952 | PMC:PMC10492091
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Hui Zhao Lingcun Qin Ruyi Wang Dejie Qu Suting Li Source Type: research
A pan-cancer analysis of pituitary tumor-transforming 3, pseudogene
CONCLUSION: Our pan-cancer based findings provided a comprehensive account of the oncogenic role and utilization of PTTG3P as a novel molecular biomarker of ESCA and HNSC.PMID:37692950 | PMC:PMC10492052
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Jie Li Saima Naz Shaikh Arsalan Ahmed Uqaili Hilal Nasir Rabeea Zia Muhammad Aitzaz Akram Fahim Ali Jawad Salman Sohail Mohamed Ragab AbdelGawwad Saeedah Musaed Almutairi Mohamed S Elshikh Muhammad Jamil Rabab Ahmed Rasheed Source Type: research
Raloxifene, a SERM targets PD-L1: an in-silico study
CONCLUSIONS: PD-L1 is a potential target of the SERM raloxifene in-silico. Overall, this study is one step further towards immune checkpoint blockade using small-molecule inhibitors.PMID:37692949 | PMC:PMC10492081
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Chirag Chopra Tenzen Yodun Harpreet Singh Bhupender Singh Shashank K Singh Umesh Goutam Source Type: research
FOXO1 regulates NLRP3 inflammasome proteins in LPS-induced cardiotoxicity
CONCLUSION: FOXO1 overexpression attenuated apoptosis, ROS generation, and inflammation, whereas FOXO1 inhibition aggravated LPS-induced cardiomyocyte injury via the NLRP3 inflammasome signaling pathway.PMID:37692952 | PMC:PMC10492091
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Hui Zhao Lingcun Qin Ruyi Wang Dejie Qu Suting Li Source Type: research
A pan-cancer analysis of pituitary tumor-transforming 3, pseudogene
CONCLUSION: Our pan-cancer based findings provided a comprehensive account of the oncogenic role and utilization of PTTG3P as a novel molecular biomarker of ESCA and HNSC.PMID:37692950 | PMC:PMC10492052
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Jie Li Saima Naz Shaikh Arsalan Ahmed Uqaili Hilal Nasir Rabeea Zia Muhammad Aitzaz Akram Fahim Ali Jawad Salman Sohail Mohamed Ragab AbdelGawwad Saeedah Musaed Almutairi Mohamed S Elshikh Muhammad Jamil Rabab Ahmed Rasheed Source Type: research
Raloxifene, a SERM targets PD-L1: an in-silico study
CONCLUSIONS: PD-L1 is a potential target of the SERM raloxifene in-silico. Overall, this study is one step further towards immune checkpoint blockade using small-molecule inhibitors.PMID:37692949 | PMC:PMC10492081
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Chirag Chopra Tenzen Yodun Harpreet Singh Bhupender Singh Shashank K Singh Umesh Goutam Source Type: research
FOXO1 regulates NLRP3 inflammasome proteins in LPS-induced cardiotoxicity
CONCLUSION: FOXO1 overexpression attenuated apoptosis, ROS generation, and inflammation, whereas FOXO1 inhibition aggravated LPS-induced cardiomyocyte injury via the NLRP3 inflammasome signaling pathway.PMID:37692952 | PMC:PMC10492091
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Hui Zhao Lingcun Qin Ruyi Wang Dejie Qu Suting Li Source Type: research
A pan-cancer analysis of pituitary tumor-transforming 3, pseudogene
CONCLUSION: Our pan-cancer based findings provided a comprehensive account of the oncogenic role and utilization of PTTG3P as a novel molecular biomarker of ESCA and HNSC.PMID:37692950 | PMC:PMC10492052
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Jie Li Saima Naz Shaikh Arsalan Ahmed Uqaili Hilal Nasir Rabeea Zia Muhammad Aitzaz Akram Fahim Ali Jawad Salman Sohail Mohamed Ragab AbdelGawwad Saeedah Musaed Almutairi Mohamed S Elshikh Muhammad Jamil Rabab Ahmed Rasheed Source Type: research
Raloxifene, a SERM targets PD-L1: an in-silico study
CONCLUSIONS: PD-L1 is a potential target of the SERM raloxifene in-silico. Overall, this study is one step further towards immune checkpoint blockade using small-molecule inhibitors.PMID:37692949 | PMC:PMC10492081
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Chirag Chopra Tenzen Yodun Harpreet Singh Bhupender Singh Shashank K Singh Umesh Goutam Source Type: research
FOXO1 regulates NLRP3 inflammasome proteins in LPS-induced cardiotoxicity
CONCLUSION: FOXO1 overexpression attenuated apoptosis, ROS generation, and inflammation, whereas FOXO1 inhibition aggravated LPS-induced cardiomyocyte injury via the NLRP3 inflammasome signaling pathway.PMID:37692952 | PMC:PMC10492091
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Hui Zhao Lingcun Qin Ruyi Wang Dejie Qu Suting Li Source Type: research
A pan-cancer analysis of pituitary tumor-transforming 3, pseudogene
CONCLUSION: Our pan-cancer based findings provided a comprehensive account of the oncogenic role and utilization of PTTG3P as a novel molecular biomarker of ESCA and HNSC.PMID:37692950 | PMC:PMC10492052
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Jie Li Saima Naz Shaikh Arsalan Ahmed Uqaili Hilal Nasir Rabeea Zia Muhammad Aitzaz Akram Fahim Ali Jawad Salman Sohail Mohamed Ragab AbdelGawwad Saeedah Musaed Almutairi Mohamed S Elshikh Muhammad Jamil Rabab Ahmed Rasheed Source Type: research
Raloxifene, a SERM targets PD-L1: an in-silico study
CONCLUSIONS: PD-L1 is a potential target of the SERM raloxifene in-silico. Overall, this study is one step further towards immune checkpoint blockade using small-molecule inhibitors.PMID:37692949 | PMC:PMC10492081
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Chirag Chopra Tenzen Yodun Harpreet Singh Bhupender Singh Shashank K Singh Umesh Goutam Source Type: research
