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Source: European Respiratory Journal
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Total 303 results found since Jan 2013.
Hypercoagulation as the main cause of death in COPD
Conclusion: In the literature there are many data on the main causes of death for patients with COPD, such as respiratory failure, lung cancer, pulmonary thromboembolism, but due to the high comorbidity of COPD with cardiovascular pathology, and the mechanism of mutual complications of these nosologies, according to our research, today the main causes of death for patients with COPD are cardiovascular accidents caused by hypercoagulation.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Abduganieva, E., Artikov, D., Liverko, I. Tags: Monitoring airway disease Source Type: research
COPD as an additional risk factor for cardiovascular and respiratory events in patients with respiratory viral infection
Conclusion: There is no association between respiratory viral infection and COPD with the development of CVE or RE one year after positive virus PCR, regardless of previous CVRF. Both patients with CVRF without COPD and women with CVRF have more CVE.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Zambrano Chacon, M. D. L. A., Esteban-Lucia, L., Garcia Talavera, C. S., Nieto Roca, L., Venegas Rodriguez, A. M., Fernandez Roblas, R., Pello Lazaro, A. M., Acena Navarro, A., Villar Alvarez, F. Tags: Monitoring airway disease Source Type: research
Short term effects of noninvasive ventilation on haemodynamic parameters in patients with obesity hypoventilation syndrome
Conclusion: Acute NIV resulted in reductions of heart rate and improvements in systolic intervals. SV increased after 5 nights with NIV suggesting that NIV is safe in OHS patients with OSA.Support: VEGA 1/0220/17, APPV-16-0158, VEGA 1/0208/16.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Pobeha, P., Paranicova, I., Trojova, I., Tkacova, R., Joppa, P. Tags: Noninvasive ventilatory support Source Type: research
Late Breaking Abstract - The effect of exercise rehabilitation on cardiac function, measured by cardiac MRI, in patients with pre-capillary pulmonary hypertension
Conclusion: Exercise rehabilitation in pre-capillary PH led to significant improvements in cardiac output, stroke volume and right ventricular ejection fraction (EF). Small numbers limited results. Further work is required to assess long term benefits.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: McGettrick, M., Jayasekera, G., Brewis, M., Church, C., Johnson, M., Mackenzie, A. Tags: Right ventricle Source Type: research
Influence of tobacco smoking on the state of endothelial function in residents of the Arctic zone of Western Siberia
We examined a total of 367 residents (29.7% of men, mean age of 47.8±13.5 years) during research expeditions in the village of Krasnosel’kup, village of Tolka and Ratta of Krasnoselkupsky district.The state of the vascular system, its ability to provide adequate blood supply to organs and tissues, was studied by the parameters of the vascular stiffness index (blood flow rate, SI, m/s). We studied a sample of values of the index of rigidity of vessels of above normal occur significantly more often among smokers of the respondents (U-7103.5; p=0.02) than non-smokers. In the analysis of the parameters of the refl...
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Popov, A., Protasova, I., Lobanov, A., Andronov, S., Kochkin, R. Tags: Tobacco, smoking control and health educ. Source Type: research
Platelet count as an evolution marker of late mortality and cardiovascular events after an episode of community-acquired pneumonia
Conclusions: The evolution of circulating PC between admission and early stage evolution is related to higher risk of MACE in CAP patients during the post-episode year. Furthering the study of platelets and their activation could be useful as prognostic biomarkers in order to strengthen the prevention of long-term cardiovascular events.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Luquero-Bueno, S., Galvan-Roman, J. M., Curbelo, J., Lancho-Sanchez, A., Roy-Vallejo, E., Ortega-Gomez, M., Gomez, M., Mateo-Jimenez, G., Manzaneque-Pradales, M., Aspa Marco, J. Tags: Respiratory infections Source Type: research
Frequency of occurrence of risk factors of cardiovascular diseases and assessment of the total cardiovascular risk in patients with chronic obstructive pulmonary disease (COPD)
Conclusion: in 75% of patients with COPD, an increased 10-year risk of all fatal complications of atherosclerosis is determined. The study indicates the need to assess the risk by SCORE in patients with initial manifestations of COPD in order to timely correction of the identified risk factors for cardiovascular disease.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Klester, K., Klester, E., Zharikov, A., Balitskaya, A., Denisova, A. Tags: General practice and primary care Source Type: research
MnTBAP reduces pulmonary vascular remodeling in experimental pulmonary arterial hypertension
Conclusion: MnTBAP treatment can partly reverse RV afterload and pulmonary vascular remodeling in established experimental PAH. Together with the improved cardiac function, MnTBAP may be a promising intervention for PAH.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Sun, X.-Q., Gomez-Puerto, M. C., Schalij, I., Vonk-Noordegraaf, A., De Man, F. S., Ten Dijke, P., Bogaard, H.-J. Tags: Pulmonary hypertension Source Type: research
Predictors of physical activity in pulmonary arterial and chronic thromboembolic pulmonary hypertension
Conclusions: Daily physical activity as steps/day assessed in patients newly diagnosed with PAH/CTEPH did not well correlate with invasive hemodynamics at rest nor during exercise, but very well with the 6MWD. Whether daily activity assessments provide additional information to simple walk distance on risk factor profiles during follow-up in patients with PAH/CTEPH remains to be clarified.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Saxer, S., Lichtblau, M., Berlier, C., Hasler, E., Schwarz, E., Ulrich, S. Tags: Pulmonary hypertension Source Type: research
Late Breaking Abstract - FACE: Cluster phenotyping predicting outcomes in a prospective multicenter cohort study of chronic heart failure (CHF) patients with central sleep disorder breathing (SDB) indicated for adaptive servo ventilation (ASV)
Discussion: A phenogroup analysis including cardiac functions, SDB and ASV acceptance is promising in predicting outcomes of CHF patients.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Tamisier, R., Bailly, S., Damy, T., Davy, J.-M., Goutorbe, F., Lavergne, F., Levy, P., Palot, A., Verbraecken, J., DOrtho, M.-P., Pepin, J.-L. Tags: Sleep and control of breathing Source Type: research
Impact of PAP in reducing cardiovascular events in OSA patients: a 10-years follow-up
Conclusions: Although AHI presented an immediate and sustained decrease with PAP treatment, only an effective PAP adherence (especially after 24 months) seems to be effective in decreasing CV/CeV events, especially when used for more than 6 years.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Alves Moreira, A. C., Martins, N., Van Zeller, M., Drummond, M. Tags: Sleep and control of breathing Source Type: research
Development of Pulmonary Arteriovenous Malformations and Occurrence of Neurological Complications in patients with Hereditary Haemorrhagic Telangiectasia with isolated micronodules and/or intrapulmonary shunt at first screening
Conclusion: These results suggest that a close clinical and imaging monitoring is warranted in patients with isolated micronodules and /or positive TTCE at first PAVM screening.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Margelidon-Cozzolino, V., Khouatra, C., Traclet, J., Ahmad, K., Dupuis-Girod, S., Cottin, V. Tags: Clinical Problems Source Type: research
When it all comes down to pressure: right ventricular ejection fraction at cardiac catheterisation
In the present issue of the European Respiratory Journal, Heerdt et al. [1] report on the validation of right ventricularejection fraction (RVEF) calculated from a pressure curve at cardiac catheterisation. This is of great interest as right ventricular (RV) function is the main determinant of symptomatology and outcome in pulmonary hypertension [2], and RVEF accordingly adds significantly to risk stratification in these patients [3]. However, ejection fraction (EF) is a ratio of stroke volume (SV) to end-diastolic volume (EDV), with no pressure in the equation. So, how is it possible to calculate a volume ratio from pressure measurements?
Source: European Respiratory Journal - March 11, 2020 Category: Respiratory Medicine Authors: Naeije, R., Richter, M. J., Vanderpool, R., Tello, K. Tags: Editorials Source Type: research
Cardiac function and pulmonary hypertension in Central Asian highlanders at 3250 m
The question addressed by the study
Chronic exposure to hypoxia increases pulmonary artery pressure (PAP) in highlanders, but the criteria for diagnosis of high-altitude pulmonary hypertension (HAPH) are debated. We assessed cardiac function and PAP in highlanders at 3250 m and explored HAPH prevalence using different definitions.
Patients and methods
Central Asian highlanders free of overt cardiorespiratory disease, permanently living at 2500–3500 m compared to age-matched lowlanders living <800 m. Participants underwent echocardiography close to their altitude of residence (at 3250 m versus ...
Source: European Respiratory Journal - August 19, 2020 Category: Respiratory Medicine Authors: Lichtblau, M., Saxer, S., Furian, M., Mayer, L., Bader, P. R., Scheiwiller, P. M., Mademilov, M., Sheraliev, U., Tanner, F. C., Sooronbaev, T. M., Bloch, K. E., Ulrich, S. Tags: Pulmonary vascular disease Original Articles: Pulmonary hypertension Source Type: research
Iron bioavailability and cardiopulmonary function during ascent to very high altitude
More than one hundred million people reside worldwide at altitudes in excess of 2500 m above sea level. In the millions more who sojourn at high altitude for recreational, occupational or military pursuits, hypobaric hypoxia drives physiological changes affecting the pulmonary circulation, haematocrit and right ventricle (RV) [1]. Coincident with these, maximal left ventricular (LV) stroke volume (SV) falls [2], with a reduction of 20% reported after a 2-week stay at 4300 m [3]. A rise in heart rate (HR) compensates at rest and during submaximal exercise but is insufficient during maximal intensity exercise, cons...
Source: European Respiratory Journal - September 16, 2020 Category: Respiratory Medicine Authors: Holdsworth, D. A., Frise, M. C., Bakker-Dyos, J., Boos, C., Dorrington, K. L., Woods, D., Mellor, A., Robbins, P. A. Tags: Original Articles: Research letters Source Type: research
