• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Asymmetry of medullary veins on multiphase CT-angiography in patients with acute ischemic stroke
The management of acute ischemic stroke (AIS) has rapidly evolved over the last decade with the advancement in neuroimaging selection methods and endovascular treatment techniques. CT perfusion (CTP) with automated post-processing is the most widely used technique for extended-time window selection of patients for intra-arterial interventions based on recent clinical trials.1,2 CTP provides predictive information about stroke outcome, however the predictive ability remains moderate with area under the curve (AUC) approximately 0.6.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: A.A. Drozdov, R. Javan, C.R. Leon Guerrero, A.D. Sparks, M.R. Taheri Source Type: research

Standardized Fabrication Method of Human-Derived Emboli with Histologic and Mechanical Quantification for Stroke Research
Rapid and immediate perfusion of ischemic brain tissue with mechanical thrombectomy devices has become the cornerstone treatment in large vessel occlusion (LVO) stroke.1 Although stent retrievers and suction catheters have proven their value in large clinical trials, they have several limitations, including low rates of first-pass recanalization2 and low overall rates of complete recanalization.3 The development of new technologies to more rapidly and completely recanalize LVO in stroke relies on accurate testing phantoms and embolus analogs (EAs).
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2020 Category: Neurology Authors: Yang Liu, Adithya S. Reddy, Joshua Cockrum, Miranda C. Ajulufoh, Yihao Zheng, Albert J. Shih, Aditya S. Pandey, Luis E. Savastano Source Type: research

Effect of Sex on Clinical Outcome and Imaging after Endovascular Treatment of Large-Vessel Ischemic Stroke
In this study we assess the effect of sex on radiological and functional outcomes in EVT-treated acute stroke patients and determine if differences in baseline perfusion status between men and women might account for differences in outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2020 Category: Neurology Authors: Jelle Demeestere, S ören Christensen, Michael Mlynash, Christian Federau, Gregory W. Albers, Robin Lemmens, Maarten G. Lansberg Source Type: research

CT Perfusion Maps Improve Detection of M2-MCA Occlusions in Acute Ischemic Stroke
A growing body of literature supports mechanical thrombectomy-based endovascular therapy for M2-MCA occlusions in eligible patients with acute ischemic stroke (AIS).1 –5 This is because endovascular treatment for M2-MCA occlusions is technically feasible and leads to improved patient outcomes, despite a potential increased risk of hemorrhage.4,5 Not uncommonly, these patients undergo a single or multi-phase CT angiogram (CTA) study for LVO detection. In patient s who present in the late stroke window (6–24 h since last known normal), the CT Perfusion (CTP) study is generally performed along with a CTA study to aid in patient triage.
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2022 Category: Neurology Authors: Girish Bathla, Ravishankar Pillenahalli Maheshwarappa, Neetu Soni, Minako Hayakawa, Sarv Priya, Edgar Samaniego, Santiago Ortega-Gutierrez, Colin P. Derdeyn Source Type: research

Hypoperfusion Intensity Ratio is Associated with Stroke Mechanism in Patients Undergoing Mechanical Thrombectomy
Hypoperfusion Intensity Ratio (HIR), defined as Tmax>10s/Tmax>6s on computed tomography perfusion (CTP), and stroke mechanisms have been independently correlated with angiographic collaterals and patient outcomes. Slowly developing atherosclerotic stenosis may foster collateral development, whereas cardioembolic occlusion may occur before collaterals mature. We hypothesized that favorable HIR is associated with large artery atherosclerosis (LAA) stroke mechanism and good clinical outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2022 Category: Neurology Authors: Ahmad A. Ballout, Richard B Libman, Julia R. Schneider, Marc S. Ayoub, Jason J. Wang, Athos Patsalides, Jeffrey M Katz Source Type: research

Feasibility of deconvolution-based multiphase CT angiography perfusion maps in acute ischemic stroke: Simulation and concordance with CT perfusion
Integration of CT perfusion (CTP) with requisite non-contrast CT and CT angiography (CTA) stroke imaging may allow efficient stroke lesion volume measurement. Using surrogate images from CTP, we simulated the feasibility of using multiphase CTA (mCTA) to generate perfusion maps and assess target mismatch profiles.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2022 Category: Neurology Authors: Kevin J. Chung, Alexander V. Khaw, Sachin K. Pandey, Donald H. Lee, Jennifer L. Mandzia, Ting-Yim Lee Source Type: research

Autonomic function may mediate the neuroprotection of remote ischemic postconditioning in stroke: A randomized controlled trial
Acute ischemic stroke(AIS) is one of the leading causes of death and long-lasting disability on a global level, with an increased global burden in the past two decades.1,2 Early restoration of blood flow is currently recognized as the most effective therapy for AIS. However, rapid reperfusion after a certain period of ischemia could paradoxically induce ischemia-perfusion injury (IRI), which can promote neurovascular inflammation by inducing the generation of cytokines, and thus aggravate stroke severity and adverse neurological outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - June 15, 2023 Category: Neurology Authors: Hao Liang, Richun Ye, Xiaopei Zhang, Huanwen Ye, Wenwei Ouyang, Shuang Cai, Lin Wei Source Type: research

Intra-arterial Administration of Papaverine during Mechanical Thrombectomy for Acute Ischemic Stroke
The use of stent retrievers for mechanical thrombectomy in acute ischemic stroke may induce significant vasospasm, which at the early phases of reperfusion may be crucial for rethrombosis of the recanalized vessel. We aimed to study whether the use of intra-arterial papaverine in selected cases of vasospasm was associated with improved cerebral perfusion, arterial reocclusion, or increased hemorrhagic complications.
Source: Journal of Stroke and Cerebrovascular Diseases - November 13, 2014 Category: Neurology Authors: Gerasimos Baltsavias, Susmitha Yella, Rahman Abdul Al Shameri, Andreas Luft, Anton Valavanis Source Type: research

Inter-rater Agreement in Three Perfusion-Computed Tomography Evaluation Methods before Endovascular Therapy for Acute Ischemic Stroke
There is ongoing debate on which method of perfusion computed tomography (PCT) evaluation in ischemic stroke is the most appropriate for improved selection of patients for endovascular treatment. We sought to test different assessment methods for inter-rater reliability.
Source: Journal of Stroke and Cerebrovascular Diseases - February 2, 2016 Category: Neurology Authors: A.V. Khaw, A. Angermaier, P. Michel, M. Kirsch, C. Kessler, S. Langner Source Type: research

Good Clinical and Radiological Correlation from Standard Perfusion Computed Tomography Accurately Identifies Salvageable Tissue in Ischemic Stroke
It has been debated whether the penumbral pattern, as identified using multimodal imaging, is a specific marker of tissue viability in ischemic stroke. We assessed whether perfusion computed tomography (PCT) accurately identifies salvageable tissue and helps predict postreperfusion outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - February 5, 2016 Category: Neurology Authors: Michal M. Kawiorski, Agustina Vicente, Daniel Lourido, Alfonso Muriel, Eduardo Fandiño, José C. Méndez, Víctor Sánchez-González, Alba Aguado, Rodrigo Álvarez-Velasco, María Alonso de Leciñana Source Type: research

Stroke Presentation of Acute Type A Aortic Dissection with 100% Perfusion-Weighted Imaging–Diffusion-Weighted Imaging Mismatch: A Call for Urgent Action
Acute stroke in the setting of acute type A aortic dissection is not rare and may contraindicate immediate surgery. Evaluating irreversible brain damage is critical in this setting and magnetic resonance imaging is a key determinant in the decision of selecting surgical over medical treatment for these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 7, 2016 Category: Neurology Authors: Gilles Amr, Gregoire Boulouis, Nicolas Bricout, Thomas Modine, Georges Fayad, Pierre Aguettaz, Mohamad Koussa Tags: Case Studies Source Type: research

Susceptibility–Diffusion Mismatch in Hyperacute Stroke: Correlation with Perfusion–Diffusion Mismatch and Clinical Outcome
A prominent vein (PV) on susceptibility-weighted imaging (SWI) was recently proposed to be a marker of the penumbra. We aimed to compare the utility of SWI and perfusion-weighted imaging (PWI) sequences for the evaluation of the penumbra in hyperacute middle cerebral artery (MCA) stroke, and to determine whether SWI–DWI mismatch is a neuroimaging marker of clinical outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - April 13, 2016 Category: Neurology Authors: Maelle Dejobert, Xavier Cazals, Mariam Annan, Séverine Debiais, Marie-Agnes Lauvin, Jean-Philippe Cottier Source Type: research

Susceptibility –Diffusion Mismatch in Hyperacute Stroke: Correlation with Perfusion–Diffusion Mismatch and Clinical Outcome
A prominent vein (PV) on susceptibility-weighted imaging (SWI) was recently proposed to be a marker of the penumbra. We aimed to compare the utility of SWI and perfusion-weighted imaging (PWI) sequences for the evaluation of the penumbra in hyperacute middle cerebral artery (MCA) stroke, and to determine whether SWI –DWI mismatch is a neuroimaging marker of clinical outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - April 13, 2016 Category: Neurology Authors: Maelle Dejobert, Xavier Cazals, Mariam Annan, S éverine Debiais, Marie-Agnes Lauvin, Jean-Philippe Cottier Source Type: research

Different Perfusion Patterns in a Patient with Acute Ischemic Stroke
A 29-year-old male patient with aphasia and mild weakness of the right arm arrived at the emergency room 4 hours after symptom onset. The computed tomography perfusion showed a typical delay in the time-based maps in the left occipital lobe and another hyperperfused area in the left frontal lobe. The follow-up magnetic resonance imaging confirmed cortical ischemic lesions in both areas. This case shows that besides hypoperfusion, hyperperfusion can also be found in the first stages of acute stroke, and it is highly suggestive of established ischemic lesions.
Source: Journal of Stroke and Cerebrovascular Diseases - March 9, 2017 Category: Neurology Authors: Salvatore Rudilosso, Carlos Laredo, Xabier Urra, Ángel Chamorro Tags: Case Studies Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10