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Etiological Classification of Stroke in Patients with Chagas Disease Using TOAST, Causative Classification System TOAST, and ASCOD Phenotyping
Cardioembolism is considered a major pathophysiological mechanism in patients with ischemic stroke (IS) and Chagas disease (CD). However, a previous study reported that other stroke subtypes are present in more than 40% of CD patients according to the TOAST classification. Therefore, the aim of our study was to evaluate the etiologic classification of stroke in patients with CD using the Causative Classification System (CCS), the ASCOD, and the TOAST classifications in a prospective cohort of patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2017 Category: Neurology Authors: Rodrigo de Paiva Bezerra, Maram élia Araújo de Miranda Alves, Adriana Bastos Conforto, Daniela Laranja Gomes Rodrigues, Gisele Sampaio Silva Source Type: research

Comments on Etiological Classification of Stroke in Patients with Chagas Disease Using TOAST, Causative Classification System TOAST, and ASCOD Phenotyping
We have read with great interest the article by Bezerra et  al,1 in which an etiological classification of stroke in patients with Chagas heart disease using different systems is presented. By studying a tertiary referral center population composed of 32 patients with Chagas disease with stroke, the authors were able to show that although cardioembolic str oke affects the majority of patients, atherosclerosis and small-vessel occlusion still were important causes of stroke in patients with this condition.
Source: Journal of Stroke and Cerebrovascular Diseases - February 21, 2018 Category: Neurology Authors: Reinaldo B. Bestetti, Renata Dellalibera-Joviliano, Luc élio B. Couto Tags: Letter to the Editor Source Type: research

COX-2 rs20417 Polymorphism Is Associated with Stroke and White Matter Disease
To investigate the effect of COX-2 polymorphism and its product, prostaglandin E2 (PGE2), on stroke risk in an endemic area for Chagas disease. In a separate cohort, to investigate the effect of COX-2 polymorphisms on the total burden of cerebral white matter disease.
Source: Journal of Stroke and Cerebrovascular Diseases - May 6, 2015 Category: Neurology Authors: Jamary Oliveira-Filho, Ana C.P. Ornellas, Cathy R. Zhang, Luciana M.B. Oliveira, Théo Araújo-Santos, Valeria M. Borges, Laís M.G.B. Ventura, Francisco J.F.B. Reis, Roque Aras, André M. Fernandes, Jonathan Rosand, Steven M. Greenberg, Karen L. Furie, N Source Type: research

Artificial Inteligence-Based Decision for the Prediction of Cardioembolism in Patients with Chagas Disease and Ischemic Stroke
Chagas disease (CD) and ischemic stroke (IS) have a close, but poorly understood, association. There is paucity of evidence on the ideal secondary prophylaxis and etiological determination, with few cardioembolic patients being identified.
Source: Journal of Stroke and Cerebrovascular Diseases - August 13, 2021 Category: Neurology Authors: Vin ícius Viana Abreu Montanaro, Thiago Falcão Hora, Agostinho Alencar Guerra, Gisele Sampaio Silva, Rodrigo de Paiva Bezerra, Jamary Oliveira-Filho, Leila Souza Brito Santos, Eduardo Sousa de Melo, Luciana Patrizia Alves de Andrade, Wilson Alves de Oli Source Type: research