COX-2 rs20417 Polymorphism Is Associated with Stroke and White Matter Disease

To investigate the effect of COX-2 polymorphism and its product, prostaglandin E2 (PGE2), on stroke risk in an endemic area for Chagas disease. In a separate cohort, to investigate the effect of COX-2 polymorphisms on the total burden of cerebral white matter disease.

Source: Journal of Stroke and Cerebrovascular Diseases - May 6, 2015 Category: Neurology Authors: Jamary Oliveira-Filho, Ana C.P. Ornellas, Cathy R. Zhang, Luciana M.B. Oliveira, Théo Araújo-Santos, Valeria M. Borges, Laís M.G.B. Ventura, Francisco J.F.B. Reis, Roque Aras, André M. Fernandes, Jonathan Rosand, Steven M. Greenberg, Karen L. Furie, N Source Type: research