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Specialty: Neuroscience
Source: CNS Neuroscience and Therapeutics
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Total 476 results found since Jan 2013.
Unfavorable Outcome of Thrombolysis in Chinese Patients with Cardioembolic Stroke: a Prospective Cohort Study.
CONCLUSIONS: Patients with cardioembolic stroke had more SICH after thrombolysis, and worse clinical outcome at 3-month follow-up compared with those with LAA. This emphasizes the importance of preventing cardioembolism.
PMID: 26096605 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - June 20, 2015 Category: Neuroscience Authors: Wang XG, Zhang LQ, Liao XL, Pan YS, Shi YZ, Wang CJ, Wang YL, Liu LP, Zhao XQ, Wang YJ, Li D, Wang CX, Thrombolysis Implementation and Monitoring of acute ischemic Stroke in China (TIMS-China) Investigators Tags: CNS Neurosci Ther Source Type: research
Chinese Consensus Statement on the Evaluation and Intervention of Collateral Circulation for Ischemic Stroke.
CONCLUSION: Assessment of collateral circulation is crucial for selecting therapeutic options, predicting infarction volume and making prognosis after ischemic stroke. Data is still needed to provide therapeutic evidence for many new developed technologies. Until more evidence is available, the clinical significance of applying the new technologies is unclear and perhaps limited.
PMID: 24495505 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - February 5, 2014 Category: Neuroscience Authors: Liu LP, Xu AD, Wong LK, Wang DZ, Wang YJ, Expert consensus group of the evaluation & intervention of collateral circulation for ischemic stroke Tags: CNS Neurosci Ther Source Type: research
Mediation effect of stroke recurrence in the association between post-stroke interleukin-6 and functional disability
CONCLUSIONS: Stroke recurrence mediates less than 20% of the association between IL-6 and functional outcome at 90 days among patients with acute ischemic stroke. In addition to typical secondary prevention strategies for preventing stroke recurrence, more attention should be paid to novel anti-inflammatory therapy to improve functional outcomes directly.PMID:37287421 | DOI:10.1111/cns.14289
Source: CNS Neuroscience and Therapeutics - June 8, 2023 Category: Neuroscience Authors: Hong-Qiu Gu Kai-Xuan Yang Jie-Jie Li Jin-Xi Lin Jing Jing Yun-Yun Xiong Xing-Quan Zhao Yi-Long Wang Li-Ping Liu Xia Meng Yong Jiang Hao Li Yong-Jun Wang Zi-Xiao Li Source Type: research
Elevated gamma-glutamyl transferase levels are associated with stroke recurrence after acute ischemic stroke or transient ischemic attack
CONCLUSION: This study demonstrated that elevated GGT levels were positively associated with an increased risk of stroke adverse outcomes, namely, recurrence, ischemic stroke, and combined vascular events.PMID:35789538 | DOI:10.1111/cns.13909
Source: CNS Neuroscience and Therapeutics - July 5, 2022 Category: Neuroscience Authors: Siqi Li Anxin Wang Xue Tian Yingting Zuo Xia Meng Yumei Zhang Source Type: research
Soluble lectin-like oxidized low-density Lipoproteinreceptor-1 and recurrent stroke: A nested case-control study
CONCLUSIONS: sLOX-1 was positively associated with the risk of recurrent stroke, which may be a candidate biomarker to improve risk stratification of recurrent stroke.PMID:35909324 | DOI:10.1111/cns.13932
Source: CNS Neuroscience and Therapeutics - August 1, 2022 Category: Neuroscience Authors: Anxin Wang Xue Tian Jie Xu Hao Li Qin Xu Pan Chen Xia Meng Yongjun Wang Source Type: research
Targeting CD36-Mediated Inflammation Reduces Acute Brain Injury in Transient, but not Permanent, Ischemic Stroke.
CONCLUSION: The study revealed that targeting CD36 has a beneficial effect on transient but not permanent focal ischemic stroke. The study thus precludes a generalized strategy targeting CD36 in ischemic stroke and suggests careful consideration of types of stroke and associated pathology in developing stroke therapies.
PMID: 25216018 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - September 12, 2014 Category: Neuroscience Authors: Kim E, Tolhurst AT, Szeto HH, Cho S Tags: CNS Neurosci Ther Source Type: research
Treatment with an Angiopoietin-1 mimetic peptide promotes neurological recovery after stroke in diabetic rats.
CONCLUSION: Delayed VT treatment (24 h after stroke) significantly improves neurological function, promotes vascular and white matter remodeling, and decreases inflammation in the ischemic brain after stroke in T1DM rats.
PMID: 33346402 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - December 21, 2020 Category: Neuroscience Authors: Venkat P, Ning R, Zacharek A, Culmone L, Liang L, Landschoot-Ward J, Chopp M Tags: CNS Neurosci Ther Source Type: research
Perioperative stroke: A perspective on challenges and opportunities for experimental treatment and diagnostic strategies
CNS Neurosci Ther. 2022 Feb 27. doi: 10.1111/cns.13816. Online ahead of print.ABSTRACTPerioperative stroke is an ischemic or hemorrhagic cerebral event during or up to 30 days after surgery. It is a feared condition due to a relatively high incidence, difficulties in timely detection, and unfavorable outcome compared to spontaneously occurring stroke. Recent preclinical data suggest that specific pathophysiological mechanisms such as aggravated neuroinflammation contribute to the detrimental impact of perioperative stroke. Conventional treatment options are limited in the perioperative setting due to difficult diagnosis an...
Source: CNS Neuroscience and Therapeutics - February 28, 2022 Category: Neuroscience Authors: Xia Jin Peiying Li Dominik Michalski Shen Li Yueman Zhang Jukka Jolkkonen Lili Cui Nadine Didwischus Wei Xuan Johannes Boltze Source Type: research
Visual field impairment predicts recurrent stroke after acute posterior circulation stroke and transient ischemic attack.
CONCLUSIONS: VFI is an independent predictor of recurrent VB stroke and TIA.
PMID: 29293287 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - January 2, 2018 Category: Neuroscience Authors: Deng YM, Chen DD, Wang LY, Gao F, Sun X, Liu L, Lei K, Wang SR, Mo DP, Ma N, Song LG, Huo XC, Xu XT, Yan TY, Miao ZR Tags: CNS Neurosci Ther Source Type: research
