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Predicting Post –Liver Transplant Outcomes—Rise of the Machines or a Foggy Crystal Ball?
ALTHOUGH LIVER transplantation (LT) provides a life-saving therapy to thousands of patients per year, many more die while awaiting transplantation resulting from critical organ shortages. Due to these shortages, patient selection is of paramount importance. Liver transplant programs strive to select recipients with high expected gains in life expectancy and low risks of complications. Major adverse cardiovascular events (MACE), such as myocardial infarction, heart failure, and stroke, may occur in approximately 23% of LT recipients within six months of transplantation.
Source: Journal of Cardiothoracic and Vascular Anesthesia - March 12, 2021 Category: Anesthesiology Authors: Matthew W. Vanneman, Vikram Fielding-Singh, Nima Aghaeepour Tags: Editorial Source Type: research

Predicting post-liver transplant outcomes —rise of the machines or a foggy crystal ball?
Although liver transplantation (LT) provides a life-saving therapy to thousands of patients per year, many more die while awaiting transplantation due to critical organ shortages. Due to these shortages, patient selection is of paramount importance. Liver transplant programs strive to select recipients with high expected gains in life expectancy and low risks of complications. Major adverse cardiovascular events (MACE), such as myocardial infarction, heart failure, and stroke, may occur in approximately 23% of LT recipients within 6 months of transplantation.
Source: Journal of Cardiothoracic and Vascular Anesthesia - March 12, 2021 Category: Anesthesiology Authors: Matthew W. Vanneman, Vikram Fielding-Singh, Nima Aghaeepour Tags: Editorial Source Type: research

Decannulation of a Ventricular Assist Device
BECAUSE OF the donor organ shortage, an increasing number of patients with advanced heart failure are receiving ventricular assist devices (VADs) as a bridge to transplantation or as a destination therapy.1 Patients with advanced heart failure who receive a VAD have significantly greater survival rates compared with those who are treated with only medication.2 However, short- and long-term complications of VADs still are a major concern.3 There are perioperative risks attributed to patient comorbidities; risks of surgery and anesthesia; and postoperative risks such as bleeding, thrombosis, stroke, infection, right ventricu...
Source: Journal of Cardiothoracic and Vascular Anesthesia - October 4, 2018 Category: Anesthesiology Authors: Tuan-Yen Wu Tags: Case Report Source Type: research

Inefficacy of Platelet Transfusion in a Heart Transplant Patient Under Continuous Ticagrelor
Antiplatelet agents have a predominant role in the therapeutic treatment of acute coronary syndrome (ACS) and myocardial infarction. Recently, ticagrelor has been incorporated in the European Society of Cardiology guidelines for the management of ACS with ST elevation and non-ST elevation.1 The AHA/ACC guidelines further advocate the choice of ticagrelor over clopidogrel in patients with ACS with non-ST elevation treated with an early invasive strategy.2 In fact, major studies have proven the benefits of ticagrelor on cardiovascular death, myocardial infarction, and stroke without an increase in major bleeding risk.
Source: Journal of Cardiothoracic and Vascular Anesthesia - June 15, 2017 Category: Anesthesiology Authors: Laura Filaire, Dat T. Pham, Nicolas d ’Ostrevy, Huyen T. Tran, Lionel Camilleri, Kasra Azarnoush Tags: Case Report Source Type: research

Postoperative Stroke Following Administration of Intraoperative Recombinant Tissue Plasminogen Activator for the Treatment of Intracardiac Thrombus During Liver Transplantation: A Report of Two Cases
MASSIVE INTRACARDIAC AND PULMONARY thromboembolism have an extremely high mortality during liver transplantation.1,2 The authors describe 2 cases in which intraoperative use of tissue plasminogen activator was able to reduce the thrombus size and improve hemodynamics during liver transplantation. Although both patients survived the surgery, they suffered neurologic sequelae postoperatively. The authors discuss the current understanding of the pathophysiology, diagnosis, and management of intracardiac thromboembolism during liver transplantation.
Source: Journal of Cardiothoracic and Vascular Anesthesia - October 22, 2014 Category: Anesthesiology Authors: Stephen Aniskevich, Beth L. Ladlie, Sher-Lu Pai, Dana K. Perry, Juan M. Canabal, C. Burcin Taner Tags: Case Report Source Type: research