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Specialty: Internal Medicine
Source: Mayo Clinic Proceedings
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Total 82 results found since Jan 2013.
Premature Atrial Contractions
Premature atrial contractions (PACs) can be seen in a broad spectrum of patients with and without heart disease and are often considered benign clinical phenomena. Recent studies have, however, shown an association between PACs and new-onset atrial fibrillation (AF), stroke, and all-cause mortality.1,2 Simultaneously, reporting of the association between cardiac arrhythmias such as AF, atrial structural disease, and cerebrovascular diseases such as stroke and dementia have expanded our understanding of the complex web of interaction between the heart and brain.
Source: Mayo Clinic Proceedings - May 1, 2021 Category: Internal Medicine Authors: Chaitra Janga, Malini Madhavan Tags: Editorial Source Type: research
Oral Anticoagulation in Patients With Advanced Chronic Kidney Disease and Atrial Fibrillation: Beyond Anticoagulation
The optimal approach to prevent stroke and systemic embolism in patients with advanced chronic kidney disease (CKD) and atrial fibrillation remains unresolved. We conducted a narrative review to explore areas of uncertainty and opportunities for future research. First, the relationship between atrial fibrillation and stroke is more complex in patients with advanced CKD than in the general population. The currently employed risk stratification tools do not adequately discriminate between patients deriving a net benefit and those suffering a net harm from oral anticoagulation.
Source: Mayo Clinic Proceedings - April 5, 2023 Category: Internal Medicine Authors: Sofie A.M. Dhaese, An S. De Vriese Tags: Review Source Type: research
Burden of Illness for Osteoporotic Fractures Compared With Other Serious Diseases Among Postmenopausal Women in the United States
To provide a national estimate of the incidence of hospitalizations due to osteoporotic fractures (OFs) in women; compare this with the incidence of myocardial infarction (MI), stroke, and breast cancer; and assess temporal trends in the incidence and length of hospitalizations.
Source: Mayo Clinic Proceedings - December 3, 2014 Category: Internal Medicine Authors: Andrea Singer, Alex Exuzides, Leslie Spangler, Cynthia O’Malley, Chris Colby, Karissa Johnston, Irene Agodoa, Jessica Baker, Risa Kagan Tags: Original article Source Type: research
Correction
A cover line on the November 2014 print cover was incorrect. It should read: “Risk of First-Ever Stroke in Young Patients With Atrial Fibrillation Not Recommended for Antithrombotic Therapy by Current Guidelines.” We regret the error.
Source: Mayo Clinic Proceedings - January 1, 2015 Category: Internal Medicine Tags: Correction Source Type: research
Testosterone Therapy and Cardiovascular Risk: Advances and Controversies
This article reviews those studies as well as the extensive literature on T and CV risks. A MEDLINE search was performed for the years 1940 to August 2014 using the following key words: testosterone, androgens, human, male, cardiovascular, stroke, cerebrovascular accident, myocardial infarction, heart attack, death, and mortality. The weight and direction of evidence was evaluated and level of evidence (LOE) assigned.
Source: Mayo Clinic Proceedings - January 26, 2015 Category: Internal Medicine Authors: Abraham Morgentaler, Martin M. Miner, Monica Caliber, Andre T. Guay, Mohit Khera, Abdulmaged M. Traish Tags: Special article Source Type: research
Central Neuropathic Pain Syndromes
Chronic pain is common in patients with neurologic complications of a central nervous system insult such as stroke. The pain is most commonly musculoskeletal or related to obligatory overuse of neurologically unaffected limbs. However, neuropathic pain can result directly from the central nervous system injury. Impaired sensory discrimination can make it challenging to differentiate central neuropathic pain from other pain types or spasticity. Central neuropathic pain may also begin months to years after the injury, further obscuring recognition of its association with a past neurologic injury.
Source: Mayo Clinic Proceedings - March 1, 2016 Category: Internal Medicine Authors: James C. Watson, Paola Sandroni Tags: Symposium on pain medicine Source Type: research
Achieving the Benefits of a High-Potassium, Paleolithic Diet, Without the Toxicity
The average US dietary intake of K+ is well below the current recommended nutritional requirements. This deficiency is even more striking when comparing our current intake with that of our ancestors, who consumed large amounts of dietary K+. K+ deficiency has been implicated in many diseases including cardiovascular disease, kidney stones, and osteoporosis. Importantly, dietary supplementation of K+ has favorable effects on reducing blood pressure, decreasing the risk of stroke, improving bone health, and reducing the risk of nephrolithiasis.
Source: Mayo Clinic Proceedings - March 3, 2016 Category: Internal Medicine Authors: Biff F. Palmer, Deborah J. Clegg Tags: Review Source Type: research
Impact on Outcomes of Changing Treatment Guideline Recommendations for Stroke Prevention in Atrial Fibrillation: A Nationwide Cohort Study
To investigate the impact on outcomes of changing treatment guideline recommendations by comparing the proportion of patients with atrial fibrillation (AF) recommended oral anticoagulants (OACs) under the 2011 and 2014 American College of Cardiology/American Heart Association (ACC/AHA) guidelines.
Source: Mayo Clinic Proceedings - April 7, 2016 Category: Internal Medicine Authors: Tze-Fan Chao, Chia-Jen Liu, Ta-Chuan Tuan, Kang-Ling Wang, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Tzeng-Ji Chen, Chern-En Chiang, Ming-Hsiung Hsieh, Gregory Y.H. Lip, Shih-Ann Chen Tags: Original article Source Type: research
CHA2DS2-VASc Score: A Predictor of Thromboembolic Events and Mortality in Patients With an Implantable Monitoring Device Without Atrial Fibrillation
To determine if the CHA2DS2-VASc score (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke or transient ischemic attack, vascular disease, age 65-74 years, sex category) predicts thromboembolism and death in patients without atrial fibrillation in a population with implantable cardiac monitoring devices.
Source: Mayo Clinic Proceedings - February 28, 2017 Category: Internal Medicine Authors: Christine Parsons, Salma I. Patel, Stephen Cha, Win-Kuang Shen, Santosh Desai, Alanna M. Chamberlain, Sushil Allen Luis, Maria I. Aguilar, Bart M. Demaerschalk, Farouk Mookadam, Fadi Shamoun Tags: Original article Source Type: research
Evaluation and Management of Atherosclerotic Carotid Stenosis
Medical therapies for the prevention of stroke have advanced considerably in the past several years. There can also be a role for mechanical restoration of the lumen by endarterectomy or stenting in selected patients with high-grade atherosclerotic stenosis of the extracranial carotid artery. Endarterectomy is generally recommended for patients with high-grade symptomatic carotid stenosis. Stenting is considered an option for patients at high risk of complications with endarterectomy. Whether revascularization is better than contemporary medical therapy for asymptomatic extracranial carotid stenosis is a subject of several...
Source: Mayo Clinic Proceedings - July 1, 2017 Category: Internal Medicine Authors: James F. Meschia, James P. Klaas, Robert D. Brown, Thomas G. Brott Tags: Symposium on neurosciences Source Type: research
Guideline-Adherent Antithrombotic Treatment Improves Outcomes in Patients With Atrial Fibrillation
To assess the influence of guideline-adherent vs nonadherent antithrombotic treatment (ATT) on stroke and mortality rates in an atrial fibrillation (AF) primary care population.
Source: Mayo Clinic Proceedings - August 1, 2017 Category: Internal Medicine Authors: Micha ł Mazurek, Eduard Shantsila, Deirdre A. Lane, Andreas Wolff, Marco Proietti, Gregory Y.H. Lip Tags: Original article Source Type: research
Palliative Care in Neurology
Palliative medicine is a specialty that focuses on improving the quality of life for patients with serious or advanced medical conditions, and it is appropriate at any stage of disease, including at the time of diagnosis. Neurologic conditions tend to have high symptom burdens, variable disease courses, and poor prognoses that affect not only patients but also their families and caregivers. Patients with a variety of neurologic conditions such as Parkinson disease, dementia, amyotrophic lateral sclerosis, brain tumors, stroke, and acute neurologic illnesses have substantial unmet needs that can be addressed through a combi...
Source: Mayo Clinic Proceedings - October 1, 2017 Category: Internal Medicine Authors: Maisha T. Robinson, Robert G. Holloway Tags: Symposium on neurosciences Source Type: research
Integrated Care Management of Patients With Atrial Fibrillation and Risk of Cardiovascular Events
To investigate the impact on cardiovascular events (CVEs) in a real-world population of patients with atrial fibrillation (AF) by implementing the Atrial fibrillation Better Care (ABC: A, Avoid stroke with anticoagulation; B, better symptom management; C, Cardiovascular and comorbidity risk management) pathway.
Source: Mayo Clinic Proceedings - December 11, 2018 Category: Internal Medicine Authors: Daniele Pastori, Pasquale Pignatelli, Danilo Menichelli, Francesco Violi, Gregory Y.H. Lip Tags: Original article Source Type: research
Weight and Risk of Incident Atrial Fibrillation —Body Mass Index Variability or Body Mass Gain?
Atrial fibrillation (AF) is an emerging global epidemic associated with significant morbidity and mortality. In recent decades, AF prevalence has exponentially risen and is showing no sign of abating. The condition is associated with numerous complications including stroke, heart failure, and all-cause mortality —risks that are evident even in individuals with few comorbidites.1,2 In the Asia-Pacific region, although AF prevalence is lower than that in Western countries, total AF burden is much higher in this region, in part because of larger populations and rising levels of modifiable cardiovascular risk factors.
Source: Mayo Clinic Proceedings - January 31, 2019 Category: Internal Medicine Authors: Celine Gallagher, Melissa E. Middeldorp, Prashanthan Sanders Tags: Editorial Source Type: research
Retinal Occlusion, Ischemic Stroke, and the Brain-Eye Connection
The risk of cerebral infarction associated with retinal ischemia has been the subject of an evolving debate. Several factors complicate this association, including varied types of ischemic visual events ranging from transient monocular visual loss to anterior ischemic optic neuropathy and retinal artery occlusion (branch or central); additionally, diagnostic and therapeutic options for cerebral ischemia continue to advance.
Source: Mayo Clinic Proceedings - January 31, 2019 Category: Internal Medicine Authors: Eric R. Eggenberger Tags: Editorial Source Type: research
