Filtered By:
Specialty: Internal Medicine
Source: Mayo Clinic Proceedings
This page shows you your search results in order of relevance. This is page number 2.
Order by Relevance | Date
Total 82 results found since Jan 2013.
In reply —Low-Sodium Intake: A Risk Factor for Stroke?
We are grateful to Drs Musso and Dotto1 for the appraisal of our article on low urinary sodium excretion (UNaV) as an indicator of low sodium intake and increased risk of stroke.2 We agree that the mentioned earlier study by O ’Donnell and colleagues,3 although representative of various populations by including more than 100,000 participants from 17 countries, has some limitations. In particular, the assessment of sodium intake via a single spot urine sample is a major limitation. Actual measurement of 24-hour UNaV in m ultiple urine collections (to account for day-to-day variability), as we did in the Prevention of Rena...
Source: Mayo Clinic Proceedings - March 31, 2019 Category: Internal Medicine Authors: Lyanne M. Kieneker, Michele F. Eisenga, Stephan J.L. Bakker Tags: Letter to the Editor Source Type: research
Left Atrial Appendage Occlusion for The Unmet Clinical Needs of Stroke Prevention in Nonvalvular Atrial Fibrillation
Oral anticoagulation is the dominant strategy for stroke prevention in patients with nonvalvular atrial fibrillation. However, lifelong oral anticoagulation is associated with major issues including inappropriate dosing, nonadherence, and adverse effects. Therefore, efforts have been made to develop site-specific therapy aimed to occlude the left atrial appendage, the anatomical site accountable for more than 90% of nonvalvular atrial fibrillation –related ischemic strokes. This review focuses on the growing literature to put into perspective the risk-balance ratio of left atrial appendage occlusion.
Source: Mayo Clinic Proceedings - April 4, 2019 Category: Internal Medicine Authors: David R. Holmes, Mohamad Alkhouli, Vivek Reddy Tags: Review Source Type: research
A Young Woman With A History of Stroke and Recurrent Migraine Headaches
A 34-year-old woman with a history of recurrent migraine without aura headaches, right pontine stroke, and recurrent small vessel subcortical infarcts presented to the emergency department with complaints of intermittent blurry vision and worsening headache. Magnetic resonance imaging of the brain was performed (Figure 1). Three 4-mm punch biopsies were performed on the normal skin of the right upper extremity, and a blood sample was submitted for NOTCH3 (notch receptor 3) genetic testing. Electron microscopy revealed the presence of granular osmiophilic material in the basement membrane of capillary smooth musc le cells...
Source: Mayo Clinic Proceedings - May 31, 2019 Category: Internal Medicine Authors: Emily Carr, Lana Joudeh Tags: Medical image Source Type: research
Impact of Stroke Volume Index and Left Ventricular Ejection Fraction on Mortality After Aortic Valve Replacement
To assess the impact of stroke volume index (SVI) and left ventricular ejection fraction (LVEF) on prognosis in patients with severe aortic stenosis, comparing those undergoing transcatheter aortic valve replacement (TAVR) and those with surgical AVR (SAVR).
Source: Mayo Clinic Proceedings - December 31, 2019 Category: Internal Medicine Authors: Saki Ito, Vuyisile T. Nkomo, David A. Orsinelli, Grace Lin, Joao Cavalcante, Jeffrey J. Popma, David H. Adams, Stanley J. Checuti, G. Michael Deeb, Michael Boulware, Jian Huang, Stephen H. Little, Sidney A. Cohen, Michael J. Reardon, Jae K. Oh Tags: Original article Source Type: research
Brain Volume: An Important Determinant of Functional Outcome After Acute Ischemic Stroke
To determine whether brain volume is associated with functional outcome after acute ischemic stroke (AIS).
Source: Mayo Clinic Proceedings - April 30, 2020 Category: Internal Medicine Authors: Markus D. Schirmer, Kathleen L. Donahue, Marco J. Nardin, Adrian V. Dalca, Anne-Katrin Giese, Mark R. Etherton, Steven J.T. Mocking, Elissa C. McIntosh, John W. Cole, Lukas Holmegaard, Katarina Jood, Jordi Jimenez-Conde, Steven J. Kittner, Robin Lemmens, Tags: Original article Source Type: research
Cardiorespiratory Fitness and Incident Stroke Types
To study the association between cardiorespiratory fitness (CRF) and incident stroke types.
Source: Mayo Clinic Proceedings - June 30, 2020 Category: Internal Medicine Authors: Mahmoud Al Rifai, Michael J. Blaha, Amjad Ahmed, Fatimah Almasoudi, Michelle C. Johansen, Waqas Qureshi, Sherif Sakr, Salim S. Virani, Clinton A. Brawner, Jonathan K. Ehrman, Steven J. Keteyian, Mouaz H. Al-Mallah Tags: Original article Source Type: research
Social Determinants of Health Among Non-Elderly Adults With Stroke in the United States
To examine the association of social determinants of health (SDOH) on prevalence of stroke in non-elderly adults (
Source: Mayo Clinic Proceedings - February 1, 2022 Category: Internal Medicine Authors: Safi U. Khan, Isaac Acquah, Zulqarnain Javed, Javier Valero-Elizondo, Tamer Yahya, Ron Blankstein, Salim S. Virani, Michael J. Blaha, Adnan A. Hyder, Prachi Dubey, Farhaan S. Vahidy, Miguel Cainzos-Achirica, Khurram Nasir Tags: Original article Source Type: research
Outcomes of Patients With Type 2 Myocardial Infarction Complicating Acute Ischemic Stroke
To study the patient profiles and the prognostic impact of type 2 myocardial infarction (MI) on outcomes of acute ischemic stroke (AIS).
Source: Mayo Clinic Proceedings - April 26, 2022 Category: Internal Medicine Authors: Salik Nazir, Robert W. Ariss, Abdul Mannan Khan Minhas, Keerat Rai Ahuja, Hani Jneid, George V. Moukarbel Tags: Original Article Source Type: research
Effectiveness and Safety of Clopidogrel vs Aspirin in Elderly Patients With Ischemic Stroke
To evaluate the risks of recurrent stroke and major bleeding events with clopidogrel and aspirin use among patients aged 80 years or older.
Source: Mayo Clinic Proceedings - August 1, 2022 Category: Internal Medicine Authors: Hsin-Yi Huang, Shin-Yi Lin, Aaron J. Katz, Jau-Jiuan Sheu, Fang-Ju Lin, Chi-Chuan Wang, Chung-Hsuen Wu Tags: Original article Source Type: research
Case-Based Discussion Regarding Challenges in Patient Selection and Procedural Planning in Left Atrial Appendage Occlusion
Atrial fibrillation (AF) accounts for most embolic strokes, especially in elderly individuals. Although anticoagulation is known to reduce the risk of embolic stroke, a significant proportion of patients have relative or absolute contraindications to anticoagulation. The left atrial appendage has been implicated as the major source of emboli in more than 90% of ischemic strokes in nonvalvular AF. Left atrial appendage occlusion offers an alternative for stroke prevention in patients with an elevated stroke risk (CHADS2 score ≥2 or CHA2DS2-VASc score ≥3) who have a rationale for avoiding long-term oral anticoagulation a...
Source: Mayo Clinic Proceedings - May 1, 2018 Category: Internal Medicine Authors: Sidakpal S. Panaich, Thomas Munger, Paul Friedman, Charanjit S. Rihal, David R. Holmes Tags: Review Source Type: research
79-Year-Old Man With Shortness of Breath and Fevers
A 79-year old man with a history of myocardial infarction and coronary artery bypass grafting in 2000, biventricular systolic heart failure with an ejection fraction of 27%, hypertension, persistent atrial fibrillation for which he was taking high-dose aspirin given a previous history of hemorrhagic stroke, stage 3 chronic kidney disease, left cerebellar ischemic stroke, and implantable cardioverter-defibrillator (ICD) placement 5 years previously presented to his local medical facility with a 2-day history of breathlessness, fevers, and chills.
Source: Mayo Clinic Proceedings - November 7, 2018 Category: Internal Medicine Authors: Jaskanwal D. Sara, Megha Prasad, Suraj Kapa Tags: Residents' clinic Source Type: research
White Matter Hyperintensities on Magnetic Resonance Imaging: What Is a Clinician to Do?
As a neurologist, I am often asked to see patients because they have a magnetic resonance image (MRI) of the brain showing white matter hyperintensities (WMHs). These patients, and the clinicians who refer them to me, want to know the answers to several questions: What are WMHs and what causes them? Are they the same as a stroke? Are they a marker for impending stroke, dementia, or death? Do they get worse over time and can the progression be slowed? Studies such as the one by Hasan et al1 in this issue of Mayo Clinic Proceedings have expanded our understanding of the etiology and clinical significance of WMHs.
Source: Mayo Clinic Proceedings - March 1, 2019 Category: Internal Medicine Authors: Jos é G. Merino Tags: Editorial Source Type: research
Utility of HAS-BLED and CHA2DS2-VASc Scores Among Patients With Atrial Fibrillation and Imaging Evidence of Cerebral Amyloid Angiopathy
To determine the utility of the HAS-BLED (Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, Elderly, Drugs/alcohol concomitantly) and CHA2DS2-VASc (Congestive heart failure, Hypertension, Age, Diabetes, previous Stroke/transient ischemic attack –VAScular disease) scores among patients on anticoagulation (AC) therapy for atrial fibrillation (AF) who have evidence of cerebral amyloid angiopathy (CAA).
Source: Mayo Clinic Proceedings - August 19, 2020 Category: Internal Medicine Authors: Robert Ward, Shiva Ponamgi, Christopher V. DeSimone, Stephen English, David O. Hodge, Joshua P. Slusser, Jonathan Graff-Radford, Alejandro A. Rabinstein, Samuel J. Asirvatham, David Holmes Tags: Original article Source Type: research
Geographic Inequalities in Cardiovascular Mortality in the United States: 1999 to 2018
To evaluate the trends in cardiovascular, ischemic heart disease (IHD), stroke, and heart failure mortality in the stroke belt in comparison with the rest of the United States.
Source: Mayo Clinic Proceedings - April 8, 2021 Category: Internal Medicine Authors: Vibhu Parcha, Rajat Kalra, Ana F. Best, Nirav Patel, Sarabjeet S. Suri, Thomas J. Wang, Garima Arora, Pankaj Arora Tags: Original article Source Type: research
Intracerebral Hemorrhage
Spontaneous intracerebral hemorrhage (ICH) is a medical emergency and is disproportionately associated with higher mortality and long-term disability compared with ischemic stroke. The phrase “time is brain” was derived for patients with large vessel occlusion ischemic stroke in which approximately 1.9 million neurons are lost every minute. Similarly, this statement holds true for ICH patients due to a high volume of neurons that are damaged at initial onset and during hematoma expan sion. Most cases of spontaneous ICH pathophysiologically stem from chronic hypertension and rupture of small perforating vessels off of l...
Source: Mayo Clinic Proceedings - May 2, 2021 Category: Internal Medicine Authors: Cumara B. O ’Carroll, Benjamin L. Brown, W. David Freeman Tags: Solicited review Source Type: research
