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Source: Vitamins and Hormones
Therapy: Stem Cell Therapy
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Total 1726 results found since Jan 2013.
Growth hormone receptor gene disruption
Vitam Horm. 2023;123:109-149. doi: 10.1016/bs.vh.2022.12.004. Epub 2023 Aug 24.ABSTRACTMuch of our understanding of growth hormone's (GH)'s numerous activities stems from studies utilizing GH receptor (GHR) knockout mice. More recently, the role of GH action has been examined by creating mice with tissue-specific or temporal GHR disruption. To date, 37 distinct GHR knockout mouse lines have been created. Targeted tissues include fat, liver, muscle, heart, bone, brain, macrophage, intestine, hematopoietic stem cells, pancreatic β cells, and inducible multi-tissue "global" disruption at various ages. In this chapter, a summ...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Edward O List Silvana Duran-Ortiz Prateek Kulkarni Emily Davis Patricia Mora-Criollo Darlene E Berryman John J Kopchick Source Type: research
Endocannabinoid system and epigenetics in spermatogenesis and testicular cancer
Vitam Horm. 2023;122:75-106. doi: 10.1016/bs.vh.2023.01.002. Epub 2023 Feb 6.ABSTRACTIn mammals, male germ cell development starts during fetal life and is carried out in postnatal life with the formation of sperms. Spermatogenesis is the complex and highly orderly process during which a group of germ stem cells is set at birth, starts to differentiate at puberty. It proceeds through several stages: proliferation, differentiation, and morphogenesis and it is strictly regulated by a complex network of hormonal, autocrine and paracrine factors and it is associated with a unique epigenetic program. Altered epigenetic mechanis...
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Marco Barchi Eugenia Guida Susanna Dolci Pellegrino Rossi Paola Grimaldi Source Type: research
Aberrant epigenetic regulation of estrogen and progesterone signaling at the level of endometrial/endometriotic tissue in the pathomechanism of endometriosis
Vitam Horm. 2023;122:193-235. doi: 10.1016/bs.vh.2022.11.005. Epub 2022 Dec 29.ABSTRACTEndometriosis is a term referring to a condition whereby the endometrial tissue is found outside the uterine cavity. This progressive and debilitating condition affects up to 15% of women of reproductive age. Due to the fact that endometriosis cells may express estrogen receptors (ERα, Erβ, GPER) and progesterone (P4) receptors (PR-A, PR-B), their growth, cyclic proliferation, and breakdown are similar to the processes occurring in the endometrium. The underlying etiology and pathogenesis of endometriosis are still not fully explained....
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Dariusz Szukiewicz Source Type: research
Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the amphibian intestine during metamorphosis
Vitam Horm. 2023;122:1-22. doi: 10.1016/bs.vh.2022.11.006. Epub 2022 Dec 29.ABSTRACTIn the amphibian intestine during metamorphosis, most of the larval epithelial cells undergo apoptosis, while a small number of the epithelial cells dedifferentiate into stem cells (SCs). The SCs actively proliferate and then newly generate the adult epithelium analogous to the mammalian counterpart, which is continuously renewed from the SCs throughout adulthood. This larval-to-adult intestinal remodeling can be experimentally induced by thyroid hormone (TH) through interacting with the surrounding connective tissue that develops as the st...
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Takashi Hasebe Kenta Fujimoto Atsuko Ishizuya-Oka Source Type: research
Endocannabinoid system and epigenetics in spermatogenesis and testicular cancer
Vitam Horm. 2023;122:75-106. doi: 10.1016/bs.vh.2023.01.002. Epub 2023 Feb 6.ABSTRACTIn mammals, male germ cell development starts during fetal life and is carried out in postnatal life with the formation of sperms. Spermatogenesis is the complex and highly orderly process during which a group of germ stem cells is set at birth, starts to differentiate at puberty. It proceeds through several stages: proliferation, differentiation, and morphogenesis and it is strictly regulated by a complex network of hormonal, autocrine and paracrine factors and it is associated with a unique epigenetic program. Altered epigenetic mechanis...
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Marco Barchi Eugenia Guida Susanna Dolci Pellegrino Rossi Paola Grimaldi Source Type: research
Aberrant epigenetic regulation of estrogen and progesterone signaling at the level of endometrial/endometriotic tissue in the pathomechanism of endometriosis
Vitam Horm. 2023;122:193-235. doi: 10.1016/bs.vh.2022.11.005. Epub 2022 Dec 29.ABSTRACTEndometriosis is a term referring to a condition whereby the endometrial tissue is found outside the uterine cavity. This progressive and debilitating condition affects up to 15% of women of reproductive age. Due to the fact that endometriosis cells may express estrogen receptors (ERα, Erβ, GPER) and progesterone (P4) receptors (PR-A, PR-B), their growth, cyclic proliferation, and breakdown are similar to the processes occurring in the endometrium. The underlying etiology and pathogenesis of endometriosis are still not fully explained....
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Dariusz Szukiewicz Source Type: research
Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the amphibian intestine during metamorphosis
Vitam Horm. 2023;122:1-22. doi: 10.1016/bs.vh.2022.11.006. Epub 2022 Dec 29.ABSTRACTIn the amphibian intestine during metamorphosis, most of the larval epithelial cells undergo apoptosis, while a small number of the epithelial cells dedifferentiate into stem cells (SCs). The SCs actively proliferate and then newly generate the adult epithelium analogous to the mammalian counterpart, which is continuously renewed from the SCs throughout adulthood. This larval-to-adult intestinal remodeling can be experimentally induced by thyroid hormone (TH) through interacting with the surrounding connective tissue that develops as the st...
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Takashi Hasebe Kenta Fujimoto Atsuko Ishizuya-Oka Source Type: research
Endocannabinoid system and epigenetics in spermatogenesis and testicular cancer
Vitam Horm. 2023;122:75-106. doi: 10.1016/bs.vh.2023.01.002. Epub 2023 Feb 6.ABSTRACTIn mammals, male germ cell development starts during fetal life and is carried out in postnatal life with the formation of sperms. Spermatogenesis is the complex and highly orderly process during which a group of germ stem cells is set at birth, starts to differentiate at puberty. It proceeds through several stages: proliferation, differentiation, and morphogenesis and it is strictly regulated by a complex network of hormonal, autocrine and paracrine factors and it is associated with a unique epigenetic program. Altered epigenetic mechanis...
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Marco Barchi Eugenia Guida Susanna Dolci Pellegrino Rossi Paola Grimaldi Source Type: research
Aberrant epigenetic regulation of estrogen and progesterone signaling at the level of endometrial/endometriotic tissue in the pathomechanism of endometriosis
Vitam Horm. 2023;122:193-235. doi: 10.1016/bs.vh.2022.11.005. Epub 2022 Dec 29.ABSTRACTEndometriosis is a term referring to a condition whereby the endometrial tissue is found outside the uterine cavity. This progressive and debilitating condition affects up to 15% of women of reproductive age. Due to the fact that endometriosis cells may express estrogen receptors (ERα, Erβ, GPER) and progesterone (P4) receptors (PR-A, PR-B), their growth, cyclic proliferation, and breakdown are similar to the processes occurring in the endometrium. The underlying etiology and pathogenesis of endometriosis are still not fully explained....
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Dariusz Szukiewicz Source Type: research
Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the amphibian intestine during metamorphosis
Vitam Horm. 2023;122:1-22. doi: 10.1016/bs.vh.2022.11.006. Epub 2022 Dec 29.ABSTRACTIn the amphibian intestine during metamorphosis, most of the larval epithelial cells undergo apoptosis, while a small number of the epithelial cells dedifferentiate into stem cells (SCs). The SCs actively proliferate and then newly generate the adult epithelium analogous to the mammalian counterpart, which is continuously renewed from the SCs throughout adulthood. This larval-to-adult intestinal remodeling can be experimentally induced by thyroid hormone (TH) through interacting with the surrounding connective tissue that develops as the st...
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Takashi Hasebe Kenta Fujimoto Atsuko Ishizuya-Oka Source Type: research
Endocannabinoid system and epigenetics in spermatogenesis and testicular cancer
Vitam Horm. 2023;122:75-106. doi: 10.1016/bs.vh.2023.01.002. Epub 2023 Feb 6.ABSTRACTIn mammals, male germ cell development starts during fetal life and is carried out in postnatal life with the formation of sperms. Spermatogenesis is the complex and highly orderly process during which a group of germ stem cells is set at birth, starts to differentiate at puberty. It proceeds through several stages: proliferation, differentiation, and morphogenesis and it is strictly regulated by a complex network of hormonal, autocrine and paracrine factors and it is associated with a unique epigenetic program. Altered epigenetic mechanis...
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Marco Barchi Eugenia Guida Susanna Dolci Pellegrino Rossi Paola Grimaldi Source Type: research
Aberrant epigenetic regulation of estrogen and progesterone signaling at the level of endometrial/endometriotic tissue in the pathomechanism of endometriosis
Vitam Horm. 2023;122:193-235. doi: 10.1016/bs.vh.2022.11.005. Epub 2022 Dec 29.ABSTRACTEndometriosis is a term referring to a condition whereby the endometrial tissue is found outside the uterine cavity. This progressive and debilitating condition affects up to 15% of women of reproductive age. Due to the fact that endometriosis cells may express estrogen receptors (ERα, Erβ, GPER) and progesterone (P4) receptors (PR-A, PR-B), their growth, cyclic proliferation, and breakdown are similar to the processes occurring in the endometrium. The underlying etiology and pathogenesis of endometriosis are still not fully explained....
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Dariusz Szukiewicz Source Type: research
Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the amphibian intestine during metamorphosis
Vitam Horm. 2023;122:1-22. doi: 10.1016/bs.vh.2022.11.006. Epub 2022 Dec 29.ABSTRACTIn the amphibian intestine during metamorphosis, most of the larval epithelial cells undergo apoptosis, while a small number of the epithelial cells dedifferentiate into stem cells (SCs). The SCs actively proliferate and then newly generate the adult epithelium analogous to the mammalian counterpart, which is continuously renewed from the SCs throughout adulthood. This larval-to-adult intestinal remodeling can be experimentally induced by thyroid hormone (TH) through interacting with the surrounding connective tissue that develops as the st...
Source: Vitamins and Hormones - March 2, 2023 Category: Endocrinology Authors: Takashi Hasebe Kenta Fujimoto Atsuko Ishizuya-Oka Source Type: research
