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Source: The American Journal of Cardiology
Management: Hospitals

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Total 68 results found since Jan 2013.

Comparison of In-Hospital Outcomes With Low-Dose Fibrinolytic Therapy Followed by Urgent Percutaneous Coronary Intervention Versus Percutaneous Coronary Intervention Alone for Treatment of ST-Elevation Myocardial Infarction
In patients with acute ST-elevation myocardial infarction (STEMI), a strategy of prehospital reduced dose fibrinolytic administration coupled with urgent percutaneous coronary intervention (PCI), termed FAST-PCI strategy, has been found to be superior to primary PCI (PPCI) alone. A coordinated STEMI system of care that includes FAST-PCI should offer better outcomes than a system in which prehospital diagnosis of STEMI is followed by PPCI alone. The aim of this study was to compare the in-hospital outcomes for patients treated with the FAST-PCI approach with outcomes for patients treated with the PPCI approach in a common s...
Source: The American Journal of Cardiology - March 14, 2013 Category: Cardiology Authors: Neel S. Bhatt, Amirreza Solhpour, Prakash Balan, Armin Barekatain, James J. McCarthy, Stefano Sdringola, Ali E. Denktas, Richard W. Smalling, H. Vernon Anderson Tags: Coronary Artery Disease Source Type: research

30-Year Trends in Patient Characteristics, Treatment Practices, and Long-Term Outcomes of Adults Aged 35 to 54 Years Hospitalized With Acute Myocardial Infarction
The objectives of our population-based study were to describe>3-decade-long trends in the clinical features, treatment practices, and long-term outcomes of young adults aged 35 to 54 years discharged from the hospital after AMI. The study population consisted of 2,142 residents of the Worcester (Massachusetts) metropolitan area who were hospitalized with AMI at all central Massachusetts medical centers during 16 annual periods from 1975 to 2007. Our primarily male study population had an average age of 47 years. Patients hospitalized during the most recent decade (1997 to 2007) under study were more likely to have a hist...
Source: The American Journal of Cardiology - January 15, 2014 Category: Cardiology Authors: Mayra Tisminetzky, David D. McManus, Joel M. Gore, Jorge Yarzebski, Andrew Coles, Darleen Lessard, Robert J. Goldberg Tags: Coronary Artery Disease Source Type: research

Impact of Hospital Volume on Utilization and Outcomes of Sentinel Cerebral Protection System During Transcatheter Aortic Valve Implantation
Stroke remains a serious complication of transcatheter aortic valve implantation (TAVI) with a significant impact on long-term morbidity and mortality. Although the etiology of strokes is multifactorial, most are a result of embolization of debris during the procedure.1 Multiple devices have emerged aiming to reduce the incidence of stroke through cerebral embolic protection. The Sentinel cerebral protection system (CPS) is the only Food and Drug Administration-approved device in the United States.
Source: The American Journal of Cardiology - July 13, 2022 Category: Cardiology Authors: Agam Bansal, Toshiaki Isogai, Mohamed M. Gad, Grant W. Reed, Rishi Puri, Amar Krishnaswamy, Samir R. Kapadia Source Type: research

Association of Frailty Status on the Causes and Outcomes of Patients Admitted With Cardiovascular Disease
Data are limited about the contemporary association between frailty and the causes and outcomes of patients admitted with cardiovascular diseases (CVD). Using the US National Inpatient Sample, CVD admissions of interest (acute myocardial infarction, ischemic stroke, atrial fibrillation (AF), heart failure, pulmonary embolism, cardiac arrest, and hemorrhagic stroke) were stratified by Hospital Frailty Risk Score (HFRS). Logistic regression was used to determine adjusted odds ratios (aORs) and 95% confidence intervals (CIs) of in-hospital mortality among different groups with frailty.
Source: The American Journal of Cardiology - January 24, 2023 Category: Cardiology Authors: Balamrit Singh Sokhal, Andrija Mateti ć, Muhammad Rashid, Jo Protheroe, Richard Partington, Christian Mallen, Mamas A. Mamas Source Type: research

Comparison of Procedural Success and Long-Term Outcomes of Stent Thrombosis in Coronary Bypass Grafts Versus Native Coronary Arteries
Percutaneous coronary intervention within bypass grafts accounts for a significant percentage of total interventions. Bypass graft interventions are associated with an increased risk for stent thrombosis (ST), a condition that leads to significant morbidity and mortality. Despite this, the procedural characteristics and long-term outcomes of patients with bypass-graft ST have not been reported. The aim of the present study was to evaluate the procedural success and long-term outcomes of patients presenting with ST of coronary bypass grafts. Clinical and procedural characteristics of 205 ST cases at 5 academic hospitals wer...
Source: The American Journal of Cardiology - December 20, 2012 Category: Cardiology Authors: Stephen W. Waldo, Ehrin J. Armstrong, Khung Keong Yeo, Ehtisham Mahmud, Mitul Patel, Ryan Reeves, John S. MacGregor, Reginald I. Low, Jason H. Rogers, Kendrick A. Shunk Tags: Coronary Artery Disease Source Type: research

Frequency, Determinants and Prognostic Implications of Infectious Complications After Transcatheter Aortic Valve Implantation
This study included 298 consecutive patients from 2 centers who underwent TAVI from November 2005 to November 2011. IHI during the hospital stay was defined on the basis of symptoms and signs assessed by the attending physician in the cardiac care unit or medium care unit in combination with all technical examinations performed to confirm infection. IHI after TAVI was observed in 58 patients (19.5%): urinary tract infections in 25 patients (43.1%), pneumonia in 12 patients (20.7%), and access-site infections in 7 patients (12.1%). In 12 patients (20.7%), the site of infection could not be determined, and 2 patients (3.4%) ...
Source: The American Journal of Cardiology - April 8, 2013 Category: Cardiology Authors: Robert M.A. van der Boon, Rutger-Jan Nuis, Luis M. Benitez, Nicolas M. Van Mieghem, Sergio Perez, Lidsa Cruz, Robert-Jan van Geuns, Patrick W. Serruys, Ron T. van Domburg, Antonio E. Dager, Peter P.T. de Jaegere Tags: Valvular Heart Disease Source Type: research

Outcome of Percutaneous Coronary Intervention Following Recent Surgery
The objective of this study was to determine clinical outcomes of patients undergoing PCI within 7 days after a surgical procedure. We assessed outcomes of 517 patients who underwent PCI within 7 days after a surgery across 44 hospitals from January 2010 to December 2011 from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium registry. Patients with postoperative PCI were compared with all other patients with PCI using propensity-matched analysis. Of the 65,175 patients who underwent PCI within the study period, 517 patients had undergone surgery within the previous 7 days. In unadjusted analysis, patients...
Source: The American Journal of Cardiology - September 3, 2013 Category: Cardiology Authors: John R. Hoyt, Milan Seth, Ivan Hanson, Simon Dixon, David Share, Thomas Lalonde, David Wohns, Mauro Moscucci, Hitinder S. Gurm Tags: Coronary Artery Disease Source Type: research

Comparison of Outcomes for Patients ≥75 Years of Age Treated With Pre-Hospital Reduced-Dose Fibrinolysis Followed by Percutaneous Coronary Intervention Versus Percutaneous Coronary Intervention Alone for Treatment of ST-Elevation Myocardial Infarction
A coordinated system of care for patients with ST-segment elevation myocardial infarctions that includes prehospital administration of reduced-dose fibrinolytic agents coupled with urgent percutaneous coronary intervention (PCI), termed FAST-PCI, has been shown to be at least as effective as primary PCI (PPCI) alone. However, this reduced-dose fibrinolytic strategy could be associated with increased bleeding risk, especially in elderly patients. The purpose of this study was to examine 30-day outcomes in patients aged ≥75 years with ST-segment elevation myocardial infarctions treated with either strategy. Data from 120 p...
Source: The American Journal of Cardiology - October 28, 2013 Category: Cardiology Authors: Amirreza Solhpour, Kay-Won Chang, Prakash Balan, Chunyan Cai, Stefano Sdringola, Ali E. Denktas, Richard W. Smalling, H. Vernon Anderson Tags: Coronary Artery Disease Source Type: research

Long-Term Prognostic Value and Serial Changes of Plasma N-Terminal Prohormone B-Type Natriuretic Peptide in Patients Undergoing Transcatheter Aortic Valve Implantation
The objectives of this study were to evaluate the baseline values and serial changes of N-terminal prohormone B-type natriuretic peptide (NT-proBNP) after TAVI, its related factors, and prognostic value. A total of 333 consecutive patients were included, and baseline, procedural, and follow-up (median 20 months, interquartile range 9 to 36) data were prospectively collected. Systematic NT-proBNP measurements were performed at baseline, hospital discharge, 1, 6, and 12 months, and yearly thereafter. Baseline NT-proBNP values were elevated in 86% of the patients (median 1,692 pg/ml); lower left ventricular ejection fractio...
Source: The American Journal of Cardiology - December 16, 2013 Category: Cardiology Authors: Henrique B. Ribeiro, Marina Urena, Florent Le Ven, Luis Nombela-Franco, Ricardo Allende, Marie-Annick Clavel, Abdellaziz Dahou, Mélanie Côté, Jerôme Laflamme, Louis Laflamme, Hugo DeLarochellière, Robert DeLarochellière, Daniel Doyle, Éric Dumont, Tags: Valvular Heart Disease Source Type: research

Effect of an Invasive Strategy on Outcome in Patients ≥75 Years of Age with Non-ST-Elevation Acute Coronary Syndrome
The Italian Elderly ACS study was the first randomized trial (RCT) comparing an early aggressive (EA) with an initially conservative strategy in patients with NSTEACS aged ≥75 years, with the results showing no significant benefit of EA. We evaluated the outcomes of study patients, according to the treatment actually received during hospitalization. The RCT enrolled 313 patients. The primary endpoint was the composite of death, myocardial infarction (MI), disabling stroke, and repeat hospital stay for cardiovascular causes or bleeding within 1 year.
Source: The American Journal of Cardiology - December 17, 2014 Category: Cardiology Authors: Gennaro Galasso, Stefano De Servi, Stefano Savonitto, Teresa Strisciuglio, Raffaele Piccolo, Nuccia Morici, Ernesto Murena, Claudio Cavallini, Anna Sonia Petronio, Federico Piscione Source Type: research

Relation Of Cardiac Complications In The Early Phase Of Community-Acquired Pneumonia To Long-Term Mortality And Cardiovascular Events
Community-acquired pneumonia (CAP) is complicated by cardiac events in the early phase of the disease. Aim of this study was to assess if these intra-hospital cardiac complications may account for overall mortality and cardiovascular events occurring during a long-term follow up. Three hundred and one consecutive patients admitted to the University-Hospital, Policlinico Umberto I, with CAP were prospectively recruited and followed-up for a median of 17.4 months). Primary end-point was the occurrence of death for any cause and secondary endpoint was the occurrence of cardiovascular events (cardiovascular death, non-fatal my...
Source: The American Journal of Cardiology - May 21, 2015 Category: Cardiology Authors: Roberto Cangemi, Camilla Calvieri, Marco Falcone, Tommaso Bucci, Giuliano Bertazzoni, Maria Gabriella Scarpellini, Francesco Barillà, Gloria Taliani, Francesco Violi, in collaboration with the SIXTUS study group Source Type: research

Cardiac Complications after Community-acquired Pneumonia
We read with interest the article by Cangemi et al “Relation of cardiac complications in the early phase of community –acquired pneumonia to long-term mortality and cardiovascular events”1 published in the August 5th issue of The American Journal of Cardiology. The authors show that 18% of patients with community-acquired pneumonia (CAP) study develop intra-hospital cardiac complications, defined as myocardial infarction (MI) and atrial fibrillation. Furthermore, the authors prospectively show that these cardiac complications in the early phase of CAP are associated with adverse long-term cardiovascular prognosis (wi...
Source: The American Journal of Cardiology - October 15, 2015 Category: Cardiology Authors: Carlos G. Santos-Gallego, Juan Badimon Source Type: research

A Simple and Portable Algorithm for Identifying Atrial Fibrillation in the Electronic Medical Record
Atrial fibrillation (AF) is common and increases stroke risk and mortality. Many knowledge gaps remain with respect to practice patterns and outcomes. Electronic medical records (EMR) may serve as powerful research tools if AF status can be properly ascertained. We sought to develop an algorithm for identifying individuals with and without AF in the EMR and compare it to previous methods. Using a hospital network EMR (n=5,737,846), we randomly selected 8,200 individuals seen at a large academic medical center in January 2014 to derive and validate seven AF classification schemas (4 case and 3 control) in order to construct...
Source: The American Journal of Cardiology - November 5, 2015 Category: Cardiology Authors: Shaan Khurshid, John Keaney, Patrick T. Ellinor, Steven A. Lubitz Source Type: research

Relation of Periodontitis to Risk of Cardiovascular and All-Cause Mortality (From a Danish Nationwide Cohort Study)
Periodontitis and atherosclerosis are highly prevalent chronic inflammatory diseases and it has been suggested that periodontitis is an independent risk factor of cardiovascular disease (CVD) and that a causal link may exist between the two diseases. Using Danish national registers we identified a nationwide cohort of 17,691 patients who received a hospital diagnosis of periodontitis within a 15 year period and matched them with 83,003 controls from the general population. We performed Poisson regression analysis to determine crude and adjusted incidence rate ratios (IRRs) of myocardial infarction, ischemic stroke, cardiov...
Source: The American Journal of Cardiology - May 30, 2016 Category: Cardiology Authors: Gorm Mørk Hansen, Alexander Egeberg, Palle Holmstrup, Peter Riis Hansen Source Type: research

Relation of Periodontitis to Risk of Cardiovascular and All-Cause Mortality (from a Danish Nationwide Cohort Study)
Periodontitis and atherosclerosis are highly prevalent chronic inflammatory diseases, and it has been suggested that periodontitis is an independent risk factor of cardiovascular disease (CVD) and that a causal link may exist between the 2 diseases. Using Danish national registers, we identified a nationwide cohort of 17,691 patients who received a hospital diagnosis of periodontitis within a 15-year period and matched them with 83,003 controls from the general population. We performed Poisson regression analysis to determine crude and adjusted incidence rate ratios of myocardial infarction, ischemic stroke, cardiovascular...
Source: The American Journal of Cardiology - May 30, 2016 Category: Cardiology Authors: Gorm M ørk Hansen, Alexander Egeberg, Palle Holmstrup, Peter Riis Hansen Tags: Preventive Cardiology Source Type: research