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Vaccination: Veterinary Vaccinations
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Total 283 results found since Jan 2013.
Preclinical evaluation of a SARS-CoV-2 variant B.1.351-based candidate DNA vaccine
Vaccine. 2023 Sep 17:S0264-410X(23)01091-5. doi: 10.1016/j.vaccine.2023.09.021. Online ahead of print.ABSTRACTThe SARS-CoV-2 pandemic revealed the critical shortfalls of global vaccine availability for emergent pathogens and the need for exploring additional vaccine platforms with rapid update potential in response to new variants. Thus, it remains essential, for the present evolving SARS-CoV-2/Covid-19 and future pandemics, to continuously develop and characterize new and different vaccine platforms. Here, we describe an expression-optimized DNA vaccine candidate based on the SARS-CoV-2 spike protein of the Beta variant (...
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Ria Lassauni ère Charlotta Polacek Jeanette Linnea Tingstedt Anders Fomsgaard Source Type: research
Evaluation of an iELISA for detection and quantification of rabies antibodies in domestic dog sera
Vaccine. 2023 Sep 14:S0264-410X(23)01058-7. doi: 10.1016/j.vaccine.2023.09.004. Online ahead of print.ABSTRACTMany rabies endemic-countries have recognized rabies as a public health problem that can be eliminated. As a result, some countries have started implementing small-scale vaccination programs with the aim of scaling them up. Post-vaccination serological monitoring is crucial to assess the efficacy of these programs. The recommended serological tests, the rapid fluorescent focus inhibition test, and the fluorescent antibody virus neutralization (FAVN) are accurate; however, the procedures require considerable experti...
Source: Vaccine - September 16, 2023 Category: Allergy & Immunology Authors: Ahmed Lugelo Katie Hampson Lorraine M McElhinney Felix Lankester Source Type: research
Efficacy and immunogenicity of a veterinary vaccine candidate against tick-borne encephalitis in dogs
Vaccine. 2023 Sep 14:S0264-410X(23)01089-7. doi: 10.1016/j.vaccine.2023.09.019. Online ahead of print.ABSTRACTTick-borne encephalitis (TBE) is a severe neuroinfection of humans. Dogs are also commonly infected with tick-borne encephalitis virus (TBEV). These infections are usually asymptomatic, but sometimes show clinical signs similar to those seen in humans and can be fatal. To date, there is no TBEV vaccine available for use in dogs. To address this need, a TBEV vaccine candidate for dogs based on inactivated whole virus antigen was developed. The safety, immunogenicity, and efficacy of the vaccine candidate were tested...
Source: Vaccine - September 16, 2023 Category: Allergy & Immunology Authors: Jiri Salat Milan Hunady Pavel Svoboda Lucie Strelcova Petra Strakova Andrea Fortova Martin Palus Daniel Ruzek Source Type: research
Evaluation of an iELISA for detection and quantification of rabies antibodies in domestic dog sera
Vaccine. 2023 Sep 14:S0264-410X(23)01058-7. doi: 10.1016/j.vaccine.2023.09.004. Online ahead of print.ABSTRACTMany rabies endemic-countries have recognized rabies as a public health problem that can be eliminated. As a result, some countries have started implementing small-scale vaccination programs with the aim of scaling them up. Post-vaccination serological monitoring is crucial to assess the efficacy of these programs. The recommended serological tests, the rapid fluorescent focus inhibition test, and the fluorescent antibody virus neutralization (FAVN) are accurate; however, the procedures require considerable experti...
Source: Vaccine - September 16, 2023 Category: Allergy & Immunology Authors: Ahmed Lugelo Katie Hampson Lorraine M McElhinney Felix Lankester Source Type: research
Efficacy and immunogenicity of a veterinary vaccine candidate against tick-borne encephalitis in dogs
Vaccine. 2023 Sep 14:S0264-410X(23)01089-7. doi: 10.1016/j.vaccine.2023.09.019. Online ahead of print.ABSTRACTTick-borne encephalitis (TBE) is a severe neuroinfection of humans. Dogs are also commonly infected with tick-borne encephalitis virus (TBEV). These infections are usually asymptomatic, but sometimes show clinical signs similar to those seen in humans and can be fatal. To date, there is no TBEV vaccine available for use in dogs. To address this need, a TBEV vaccine candidate for dogs based on inactivated whole virus antigen was developed. The safety, immunogenicity, and efficacy of the vaccine candidate were tested...
Source: Vaccine - September 16, 2023 Category: Allergy & Immunology Authors: Jiri Salat Milan Hunady Pavel Svoboda Lucie Strelcova Petra Strakova Andrea Fortova Martin Palus Daniel Ruzek Source Type: research
Meeting report: Towards better risk stratification, prevention and therapy of invasive GBS disease, ESPID research meeting May 2022
Vaccine. 2023 Sep 10:S0264-410X(23)01068-X. doi: 10.1016/j.vaccine.2023.09.014. Online ahead of print.ABSTRACTThe European Society of Pediatric Infectious Diseases (ESPID) hosted the third Group B Streptococcus (GBS) Research Session in Athens on 11th May 2022, providing researchers and clinicians from around the world an opportunity to share and discuss recent advances in GBS pathophysiology, molecular and genetic epidemiology and how these new insights can help in improving prevention and control of early- and late-onset GBS disease. The meeting provided a state-of-the-art overview of the existing GBS prevention strategi...
Source: Vaccine - September 12, 2023 Category: Allergy & Immunology Authors: Linde Snoek Konstantinos Karampatsas Merijn W Bijlsma Philipp Henneke Elita Jauneikaite Uzma B Khan Ruth N Zadoks Kirsty Le Doare Source Type: research
Evaluation of dynamics of immune responses and protective efficacy in piglets immunized with an inactivated porcine reproductive and respiratory syndrome vaccine candidate
In this study, we investigated the protective efficacy of an inactivated PRRS virus vaccine candidate and evaluated the differences in PRRSV specific anamnestic response in piglets when challenged with live PRRSV at two different intervals post-immunization. Six-week-old piglets were immunized intramuscularly with an inactivated, Montanide ISA-206 adjuvanted Indian PRRSV isolate, followed by a booster dose at 21 days post-immunization. Homologous live PRRS virus challenge was done on 60 and 180 days post-booster (dpb). We assessed humoral and cell-mediated immune responses at various intervals post-immunization and after c...
Source: Vaccine - September 9, 2023 Category: Allergy & Immunology Authors: Megha Katare Pandey Katherukamem Rajukumar Dhanapal Senthilkumar Subbiah Kombiah Fateh Singh Govindarajulu Venkatesh Manoj Kumar Sangeeta Shrivas Deepali Shrivastava Vijendra Pal Singh Aniket Sanyal Source Type: research
Sick as a dog? The prevalence, politicization, and health policy consequences of canine vaccine hesitancy (CVH)
Vaccine. 2023 Aug 26:S0264-410X(23)01015-0. doi: 10.1016/j.vaccine.2023.08.059. Online ahead of print.ABSTRACTCanine vaccine hesitancy (CVH) can be thought about as dog owners' skepticism about the safety and efficacy of administering routine vaccinations to their dogs. CVH is problematic not only because it may inspire vaccine refusal - which may in turn facilitate infectious disease spread in both canine and human populations - but because it may contribute to veterinary care provider mental/physical health risks. In a nationally representative survey of US adults (N = 2200), we introduce a novel survey-based instrument ...
Source: Vaccine - August 28, 2023 Category: Allergy & Immunology Authors: Matt Motta Gabriella Motta Dominik Stecula Source Type: research
Bacterial ghost cell based bivalent candidate vaccine against Salmonella Typhi and Salmonella Paratyphi A: A prophylactic study in BALB/c mice
Vaccine. 2023 Aug 23:S0264-410X(23)00992-1. doi: 10.1016/j.vaccine.2023.08.049. Online ahead of print.ABSTRACTTyphoid and emerging paratyphoid fever are a severe enteric disease worldwide with high morbidity and mortality. Licensed typhoid vaccines are in the market, but no paratyphoid vaccine is currently available. In the present study we developed a bivalent vaccine against Salmonella Typhi and Paratyphi A using a bacterial ghost platform. Bacterial ghost cells (BGs) are bacteria-derived cell membranes without cytoplasmic contents that retain their cellular morphology, including all cell surface features. Furthermore, B...
Source: Vaccine - August 25, 2023 Category: Allergy & Immunology Authors: Prolay Halder Suhrid Maiti Soumalya Banerjee Sanjib Das Moumita Dutta Shanta Dutta Hemanta Koley Source Type: research
Development and characterization of a plant-derived norovirus-like particle vaccine
CONCLUSIONS: The plant-made NoVLP vaccine was safe and immunogenic in mice and rabbits. Multi-modal vaccination, combining oral and intramuscular administration could be considered for future clinical development to maximize systemic and mucosal immune responses.PMID:37625992 | DOI:10.1016/j.vaccine.2023.08.036
Source: Vaccine - August 25, 2023 Category: Allergy & Immunology Authors: Janna R Shapiro Guadalupe Andreani Charlotte Dub é M élanie Berubé Diane Bussi ère Manon M-J Couture Mich èle Dargis Hilary E Hendin Nathalie Landry Pierre-Olivier Lavoie St éphane Pillet Brian J Ward Marc-Andr é D'Aoust Sonia Tr épanier Source Type: research
