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Source: Journal of Neurology
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Total 19 results found since Jan 2013.
Exome-based gene panel analysis in a cohort of acute juvenile ischemic stroke patients:relevance of NOTCH3 and GLA variants
ConclusionGenetic screening for Fabry ’s disease in cardioembolic and lacunar stroke as well as CADASIL in lacunar stroke might be beneficial in routine medical work-up of acute juvenile ischemic stroke.
Source: Journal of Neurology - February 28, 2023 Category: Neurology Source Type: research
Predicting functional outcomes of posterior circulation acute ischemic stroke in first 36 h of stroke onset
In conclusion, both the PC-ASPECTS and NIHSS help clinicians predict functional outcomes. PC-ASPECTS > 7 is a helpful discriminator for achieving favorable functional outcome prediction in posterior circulation acute ischemic stroke.
Source: Journal of Neurology - February 17, 2018 Category: Neurology Source Type: research
Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study
ConclusionIschemic stroke subtypes differ between the two phenotypes. Diabetes and male sex have a stronger association with PCiS than ACiS. Definitive MRI-based PCiS diagnosis aids etiological investigation and contributes additional insights into specific risk factors and mechanisms of injury in PCiS.
Source: Journal of Neurology - November 10, 2019 Category: Neurology Source Type: research
Underlying embolic and pathologic differentiation by cerebral microbleeds in cryptogenic stroke
ConclusionsCMBs were common, and age, male sex, hypertension, chronic kidney disease, and cerebral white matter diseases were related to CMBs in cryptogenic stroke. Aortic complicated lesions were associated with deep and diffuse CMBs, while prior anticoagulant therapy was related to lobar CMBs.
Source: Journal of Neurology - February 2, 2020 Category: Neurology Source Type: research
Cardiovascular magnetic resonance imaging and its role in the investigation of stroke: an update
AbstractRecent advances in complementary diagnostic exams have helped to clarify stroke etiology, not only by helping to confirm established stroke causes but also by unveiling new possible stroke mechanisms. Etiological investigation for cardioembolic stroke has benefited in the last years from information provided by studies analysing serum biomarkers, heart rhythm monitoring and imaging methods like cardiovascular magnetic resonance (CMR) imaging. CMR has been particularly important for the characterization of possible new cardioembolic stroke mechanisms including atrial cardiomyopathy, silent myocardial infarction and cardiomyopathies.
Source: Journal of Neurology - January 13, 2021 Category: Neurology Source Type: research
Stroke in supplementary motor area mimicking functional disorder: a case report
We report a 59-year-old man with previous history for myocardial infarction, referred to emergency room with an acute dense right-side hemiplegia, positive Hoover sign, asymmetrical Babinski responses and intermittent ability to move his arm in some specific reflex actions despite plegia. Since brain computed tomography scan was unremarkable we could not be sure whether his symptoms were organic or functional until a diffusion weighted imaging of magnetic resonance imaging elucidated the situation. To our knowledge, there is only one case report in the literature prior to ours, presenting a supplementary motor area stroke ...
Source: Journal of Neurology - September 28, 2019 Category: Neurology Source Type: research
Mechanical thrombectomy for ischaemic stroke in the anterior circulation: off-hours effect
ConclusionOur study did not show worse outcomes in patients treated at off-hours. This result suggests that the off-hours effect reported in other studies can be minimized by a coordinated organisation of stroke care providing similar levels of care at off-hours.
Source: Journal of Neurology - May 27, 2020 Category: Neurology Source Type: research
Dynamic changes of the direction and angle of radiographic ocular lateral deviation in patients with lateropulsion after stroke onset
ConclusionSerial changes in rOLD findings after stroke onset are different according to the responsible lesion. The direction of rOLD in most patients is in accordance with vertical perception after the acute stage of stroke.
Source: Journal of Neurology - May 9, 2023 Category: Neurology Source Type: research
Pre-procedural predictive factors of symptomatic intracranial hemorrhage after thrombectomy in stroke
ConclusionsICH after MT was associated with several pre-procedural risk factors: prior use of antiplatelet therapies, high C-reactive protein and hyperglycemia at baseline, elevated mean arterial blood pressure, and low ASPECTS.
Source: Journal of Neurology - January 3, 2021 Category: Neurology Source Type: research
A rare cause of monogenic cerebral small vessel disease and stroke: Cathepsin A-related arteriopathy with strokes and leukoencephalopathy (CARASAL)
ConclusionsCARASAL should be considered in patients with early onset or severe cerebral small vessel disease, particularly where there are prominent symptoms or signs related to brainstem involvement, such as hearing dysfunction, tinnitus or dysphagia or where there is significant thalamic and brainstem involvement on imaging.
Source: Journal of Neurology - October 31, 2022 Category: Neurology Source Type: research
White matter burden does not influence the outcome of mechanical thrombectomy
ConclusionsWMHs burden does not seem to influence clinical outcome and imaging parameters in patients treated by MT.
Source: Journal of Neurology - November 7, 2019 Category: Neurology Source Type: research
Higher blood –brain barrier permeability is associated with higher white matter hyperintensities burden
This study aimed to investigate the relationship between BBB permeability and the severity of WMH burden. Consecutive participants without symptomatic stroke history presented for physical examination were recruited in this cross-sectional stud y and divided into three WMH burden groups according to total Fazekas scores. They received dynamic contrast-enhanced-magnetic resonance imaging to measure BBB permeability, and received Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). A total of 102 participants aged 4 9–90 years (mean age of 69.82 years) were enrolled (36 with low WMH burden, 35 w...
Source: Journal of Neurology - June 26, 2017 Category: Neurology Source Type: research
Thalamic transitory ischemic attacks presenting as Jacksonian sensory march
We report on three cases in which these symptoms were caused by thalamic ischemia. Two patients presented with stereotypically recurring hemiparesthesias lasting 2 –5 min that gradually spread from the face to the arm and leg on one side. A first cerebral magnetic resonance imaging including DWI was negative in both cases, whereas new thalamic infarctions appeared on repeated imaging when clinical symptoms remained. A third case with a thalamic ischemia did not show recurring events, but also presented with purely sensory spreading symptoms. In all three cases EEG and cardiovascular diagnostics revealed normal results. ...
Source: Journal of Neurology - September 11, 2017 Category: Neurology Source Type: research
Current treatment of central retinal artery occlusion: a national survey
ConclusionsThis survey shows that there is significant variability in treatment practices for acute CRAO in the US. Because of the high cerebrovascular and cardiovascular risk reported in this population of patients, it is notable that the approach to risk factor screening is also highly variable and many programs do not routinely refer patients to an emergency department for urgent evaluation. Finally, there appears to be equipoise among treatment teams regarding the efficacy of systemic fibrinolysis, as 53% of programs report a willingness to treat at least some patients with this modality.
Source: Journal of Neurology - December 13, 2017 Category: Neurology Source Type: research
Crossed aphasia following cerebral infarction in a right-handed patient with atypical cerebral language dominance
ConclusionThe findings suggest that the patient has right-sided cerebral language dominance, or that both hemispheres have linguistic functions. Not all patients show linguistic capabilities on the side opposite hand preference. The language dominance should be predicted by a combination of clinical manifestations and functional imaging techniques.
Source: Journal of Neurology - May 18, 2018 Category: Neurology Source Type: research
