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Source: Epilepsy Curr

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Total 106 results found since Jan 2013.

Neurological Deficits in Obstructive Sleep Apnea.
Abstract OPINION STATEMENT: Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder characterized by repetitive episodes of complete or partial obstruction of the upper airway. The prevalence of this disorder is strictly dependent on its gravity. At ≥15 events/h apnea-hypopnea index (AHI), it ranges from 6 to 17% in the general population, with higher rates in men and increasing with age. The hypoxia induced by OSA severely affects the structure and function of blood vessels, culminating in mortality and morbidity. Its negative impact influences also cognitive functioning. Recent papers...
Source: Epilepsy Curr - April 1, 2017 Category: Neurology Authors: Ferini-Strambi L, Lombardi GE, Marelli S, Galbiati A Tags: Curr Treat Options Neurol Source Type: research

Recent developments in imaging of epilepsy.
Abstract PURPOSE OF REVIEW: Imaging constitutes one of the key pillars in the diagnostic workup after a first seizure as well as for the presurgical workup in epilepsy. The role of imaging in emergency situations, mainly to support the adequate diagnosis, as well as its role in planning of noninvasive image-guided therapies is less well established. Here, we provide an overview on peri-ictal imaging findings to support differential diagnosis in emergency situations and describe recent attempts toward minimal invasive therapy in the treatment of epilepsy and its comorbidities based on a combination of imaging techn...
Source: Epilepsy Curr - May 15, 2019 Category: Neurology Authors: Wiest R, Beisteiner R Tags: Curr Opin Neurol Source Type: research

Neurologic Complications of Poverty: the Associations Between Poverty as a Social Determinant of Health and Adverse Neurologic Outcomes
This study summarizes the recent literature on poverty as it contributes to neurological disease.RECENT FINDINGS: Children growing up in poverty have increased risk for cognitive deficits and behavioral disorders as reported by Noble et al. (Dev Sci. 9(6):642-54, 2006) and Farah et al. (Brain Res. 1110(1):166-74, 2006) as well as worse outcomes when it comes to epilepsy management and disease course as discussed by Camfield et al. (Epilepsia. 57(11):1826-33, 2016). In adulthood, as the number of social determinants of health increases, the incidence of stroke and severe stroke increases significantly as reported by Reshetn...
Source: Epilepsy Curr - May 5, 2021 Category: Neurology Authors: Monica Maalouf Maureen Fearon Mary Clare Lipa Hannah Chow-Johnson Linda Tayeh Daniel Lipa Source Type: research

Effectiveness and Safety of Lacosamide, A Third-generation Anti-seizure Medication, for Poststroke Seizure and Epilepsy: A Literature Review
Curr Neuropharmacol. 2023 Jun 20. doi: 10.2174/1570159X21666230616114255. Online ahead of print.ABSTRACTAdvances in stroke treatment have resulted in a dramatic reduction in stroke mortality. Nevertheless, poststroke seizures and epilepsy are issues of clinical importance affecting survivors. Additionally, stroke is the most common cause of epilepsy in older adults. Although numerous antiseizure medications exist, studies are needed to provide robust evidence of the efficacy and tolerability of these medicines for treating poststroke seizures and epilepsy. Crucially, the newer generations of antiseizure medications require...
Source: Epilepsy Curr - June 21, 2023 Category: Neurology Authors: Yu-Shiue Chen Ming-Chi Lai Tsang-Shan Chen Yung-Hsin Tseng Ya Jhen Li Chin-Wei Huang Source Type: research

Spreading Depression in Primary and Secondary Headache Disorders.
Abstract PURPOSE OF REVIEW: Spreading depression (SD) is a wave of simultaneous and near-complete depolarization of virtually all cells in brain tissue associated with a transient "depression" of all spontaneous or evoked electrical activity in the brain. SD is widely accepted as the pathophysiological event underlying migraine aura and may play a role in headache pathogenesis in secondary headache disorders such as ischemic stroke, subarachnoid or intracerebral hemorrhage, traumatic brain injury, and epilepsy. Here, we provide an overview of the pathogenic mechanisms and propose plausible hypotheses on the involv...
Source: Epilepsy Curr - May 26, 2016 Category: Neurology Authors: Chen SP, Ayata C Tags: Curr Pain Headache Rep Source Type: research

Neurologic Manifestations of the Antiphospholipid Syndrome - an Update
Curr Neurol Neurosci Rep. 2021 Jun 14;21(8):41. doi: 10.1007/s11910-021-01124-z.ABSTRACTPURPOSE OF REVIEW: In recent years, the spectrum of neurological manifestations of antiphospholipid syndrome (APS) has been growing. We provide a critical review of the literature with special emphasis on presentation, proposed mechanisms of disease, and treatment of neurological involvement in APS.RECENT FINDINGS: Although stroke is the most common cause of neurological manifestations in patients with APS, other neurological disorders have been increasingly associated with the disease, including cognitive dysfunction, headache, and epi...
Source: Epilepsy Curr - June 14, 2021 Category: Neurology Authors: Miguel Leal Rato Matilde Bandeira Vasco C Rom ão Diana Aguiar de Sousa Source Type: research