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Specialty: Cancer & Oncology
Source: Cancer Control

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Total 161 results found since Jan 2013.

Dietary diversity and risk of late-life disabling dementia in middle-aged and older adults
CONCLUSIONS: Our findings indicate that eating a variety of foods may prevent disabling dementia only among women. Thus, the habit of consuming a variety of food items has important public health implications for women.PMID:36863290 | DOI:10.1016/j.clnu.2023.02.002
Source: Cancer Control - March 2, 2023 Category: Cancer & Oncology Authors: Rei Otsuka Shu Zhang Hikaru Ihira Norie Sawada Manami Inoue Kazumasa Yamagishi Nobufumi Yasuda Shoichiro Tsugane Source Type: research

Structural Insight on GPR119 Agonist as Potential Therapy for Type II Diabetes: A Comprehensive Review
Mini Rev Med Chem. 2023 Mar 2. doi: 10.2174/1389557523666230302140658. Online ahead of print.ABSTRACTDiabetes Mellitus [DM] is a long-term metabolic condition that is characterized by excessive blood glucose. DM is the third most death-causing disease, leading to retinopathy, nephropathy, loss of vision, stroke, and cardiac arrest. Around 90% of the total cases of diabetic patients have Type II Diabetes Mellitus[T2DM]. Among various approaches for the treatment of T2DM. G protein-coupled receptors [GPCRs] 119 have been identified as a new pharmacological target. GPR119 is distributed preferentially in the pancreas β-cells...
Source: Cancer Control - March 2, 2023 Category: Cancer & Oncology Authors: Priyanshu Nema Vivek Asati Priyadarshi Kendya Twinkle Gupta Shivangi Agarwal Shivam Kori Varsha Kashaw Arun K Iyer Sushil Kumar Kashaw Source Type: research

Atrial fibrillation, cancer and anticancer drugs
Arch Cardiovasc Dis. 2023 Mar 11:S1875-2136(23)00058-X. doi: 10.1016/j.acvd.2023.02.005. Online ahead of print.ABSTRACTActive cancer is associated with an increased risk of atrial fibrillation (AF), which varies depending on the pre-existing substrate (particularly in older patients), the cancer type and stage, and the anticancer therapeutics being taken. To date, studies have not been able to identify the individual contribution of each factor. During anticancer drug therapy, AF may occur with a frequency of ≈ 15-20% according to several factors, including the patient's baseline cardiovascular toxicity risk and the AF-d...
Source: Cancer Control - March 31, 2023 Category: Cancer & Oncology Authors: Jonaz Font Paul Milliez Alexandre-Boudjema Ouazar Frederikus A Klok Joachim Alexandre Source Type: research

Home-Based Buddhist Walking Meditation Mitigates Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients: A Randomized Controlled Trial
Conclusions: Buddhist walking meditation exercise was effective in mitigating cardiotoxicity of anthracycline chemotherapy on vascular function, aerobic fitness, and quality of life in breast cancer patients. Clinical trial registration number: NCT02676531.PMID:37036793 | DOI:10.1089/jicm.2022.0778
Source: Cancer Control - April 10, 2023 Category: Cancer & Oncology Authors: Saowalak Siripanya Napa Parinyanitikul Hirofumi Tanaka Daroonwan Suksom Source Type: research

Identifying patterns of neurocognitive dysfunction through direct comparison of children with leukemia, central nervous system tumors, and sickle cell disease
CONCLUSIONS: Use of a common metric to quantify the magnitude and type of neurocognitive dysfunction across at-risk groups of participants by disease shows that participants perform below age-expected norms in multiple domains and experience dysfunction differently than one another. This approach highlights patterns of dysfunction that can inform disease- and domain-specific interventions.PMID:37036272 | DOI:10.1002/pbc.30299
Source: Cancer Control - April 10, 2023 Category: Cancer & Oncology Authors: Claire E Fraley Jamie S Neiman Charlotte R Feddersen Claire James Taylor G Jones Margit Mikkelsen Rachelle Nuss Alyssa M Schlenz Amanda C Winters Adam L Green Bruce E Compas Source Type: research

Women's reproductive traits and cerebral small-vessel disease: A two-sample Mendelian randomization study
CONCLUSION: Our findings do not convincingly support a causal effect of women's reproductive factors on CSVD. Future studies are warranted to investigate specific estrogen-related physiological changes in women, which may inform current researchers on the causal mechanisms involved in cerebral small-vessel disease progression.PMID:37064189 | PMC:PMC10098092 | DOI:10.3389/fneur.2023.1064081
Source: Cancer Control - April 17, 2023 Category: Cancer & Oncology Authors: Zhenqian Wang Jiawen Lu Weipin Weng Jie Zhang Source Type: research

Clinical and Prognostic Relevance of Cardiac Wasting in Patients With Advanced Cancer
CONCLUSIONS: Low LV mass is associated with poor functional status and increased all-cause mortality in cancer. These findings provide clinical evidence of cardiac wasting-associated cardiomyopathy in cancer.PMID:37076211 | DOI:10.1016/j.jacc.2023.02.039
Source: Cancer Control - April 20, 2023 Category: Cancer & Oncology Authors: Alessia Lena Ursula Wilkenshoff Sara Hadzibegovic Jan Porthun Lukas R ösnick Ann-Kathrin Fr öhlich Tanja Zeller Mahir Karakas Ulrich Keller Johann Ahn Lars Bullinger Hanno Riess Stuart D Rosen Alexander R Lyon Thomas F L üscher Matthias Totzeck Tienush Source Type: research

Associations of Particulate Matter Exposures With Brain Gray Matter Thickness and White Matter Hyperintensities: Effect Modification by Low-Grade Chronic Inflammation
CONCLUSION: Particulate matter exposures were associated with a reduced global cortical thickness in men with a high level of chronic inflammation. Men with a high level of chronic inflammation may be susceptible to cortical atrophy attributable to particulate matter exposures.PMID:37096314 | DOI:10.3346/jkms.2023.38.e159
Source: Cancer Control - April 25, 2023 Category: Cancer & Oncology Authors: Jaelim Cho Heeseon Jang Young Noh Seung-Koo Lee Sang-Baek Koh Sun-Young Kim Changsoo Kim Source Type: research

Tumor Genomic Profile Is Associated With Arterial Thromboembolism Risk in  Patients With Solid Cancer
CONCLUSIONS: In a large genomic tumor-profiling registry of patients with solid cancers, alterations in KRAS and STK11 were associated with an increased risk for ATE independent of cancer type. Further investigation is needed to elucidate the mechanism by which these mutations contribute to ATE in this high-risk population.PMID:37144118 | PMC:PMC10152200 | DOI:10.1016/j.jaccao.2023.01.009
Source: Cancer Control - May 5, 2023 Category: Cancer & Oncology Authors: Stephanie Feldman Dipti Gupta Babak B Navi Ka-Wai Grace Ho Peter Willeit Sean Devlin Kelly L Bolton Maria E Arcila Simon Mantha Source Type: research

Applying a nutrition security lens to the Dietary Guidelines for Americans to address metabolic health
Front Nutr. 2023 Apr 21;10:1141859. doi: 10.3389/fnut.2023.1141859. eCollection 2023.ABSTRACTNutrition security - access to food that promotes well-being and prevents or treats disease, particularly among racial and ethnic minority populations, lower income populations, and rural and remote populations - is a national priority. Leading causes of death and disability in America, such as heart disease, stroke, cancer, and diabetes that disproportionately affect minorities are linked to preventable diet-related risk factors. Mounting evidence indicates that adherence to a lower-carbohydrate dietary pattern is associated with ...
Source: Cancer Control - May 8, 2023 Category: Cancer & Oncology Authors: Jeff S Volek Jonathan Clinthorne William S Yancy Source Type: research

Cardiovascular hemodynamics in mice with tumor necrosis factor receptor-associated factor 2 mediated cytoprotection in the heart
DISCUSSION: While the reported tolerance to ischemic insults in TRAF2 overexpression mice may suggest enhanced cardiac reserve, our results indicate diminished cardiac function in these mice.PMID:37229235 | PMC:PMC10203617 | DOI:10.3389/fcvm.2023.1064640
Source: Cancer Control - May 25, 2023 Category: Cancer & Oncology Authors: Andrea G Marshall Kit Neikirk Zer Vue Heather K Beasley Edgar Garza-Lopez Larry Vang Taylor Barongan Zoe Evans Amber Crabtree Elsie Spencer Josephs Anudokem Remi Parker Jamaine Davis Dominique Stephens Steven Damo Thuy T Pham Jose A Gomez Vernat Exil Dao- Source Type: research

Influence of chronic diseases on the occurrence of depression: A 13-year follow-up study from the Survey of Health, Ageing and Retirement in Europe
This study aimed to explore the effects of types and number of chronic diseases on the risk of depression using data from the Survey of Health, Ageing and Retirement in Europe (SHARE). A self-admitted questionnaire was used to obtain data on 14 predefined chronic diseases and the European-Depression Scale (EURO-D) was used to assess depression. Among the 16,080 baseline depression-free participants aged 50+, 31.29% (5032) developed depression over 13 years. Multivariate Cox regression models showed that individuals with any chronic diseases were at higher risk of new onset depression compared to disease-free participants. ...
Source: Cancer Control - June 4, 2023 Category: Cancer & Oncology Authors: Meng-Yao Feng Yu-Han Bi Hui-Xin Wang Jin-Jing Pei Source Type: research

Alcohol consumption and risks of more than 200 diseases in Chinese men
Nat Med. 2023 Jun 8. doi: 10.1038/s41591-023-02383-8. Online ahead of print.ABSTRACTAlcohol consumption accounts for ~3 million annual deaths worldwide, but uncertainty persists about its relationships with many diseases. We investigated the associations of alcohol consumption with 207 diseases in the 12-year China Kadoorie Biobank of >512,000 adults (41% men), including 168,050 genotyped for ALDH2- rs671 and ADH1B- rs1229984 , with >1.1 million ICD-10 coded hospitalized events. At baseline, 33% of men drank alcohol regularly. Among men, alcohol intake was positively associated with 61 diseases, including 33 not defi...
Source: Cancer Control - June 8, 2023 Category: Cancer & Oncology Authors: Pek Kei Im Neil Wright Ling Yang Ka Hung Chan Yiping Chen Yu Guo Huaidong Du Xiaoming Yang Daniel Avery Shaojie Wang Canqing Yu Jun Lv Robert Clarke Junshi Chen Rory Collins Robin G Walters Richard Peto Liming Li Zhengming Chen Iona Y Millwood China Kadoo Source Type: research

Survival analysis of a comprehensive treatment strategy for internal carotid artery blowout syndrome by nasopharyngeal carcinoma
CONCLUSION: The comprehensive treatment strategy for ICA-CBS of patients with NPC significantly reduced the mortality of asphyxia due to epistaxis, reduced the incidence of CBS during nasal endoscopy, and finally improved survival rate.PMID:37309715 | DOI:10.1002/hed.27393
Source: Cancer Control - June 13, 2023 Category: Cancer & Oncology Authors: Zhouyang Zhao Qinming Liao Yimei Yang Yue Ma Xiaomeng Lu Qianhui Qiu Fei Han Lijin Huang Source Type: research

Serum folate and risk of disabling dementia: a community-based nested case-control study
CONCLUSION: In this nested case-control study with a long follow-up, low serum folate levels were associated with an increased risk of disabling dementia among Japanese individuals.PMID:37314940 | DOI:10.1080/1028415X.2023.2218533
Source: Cancer Control - June 14, 2023 Category: Cancer & Oncology Authors: Rie Kishida Kazumasa Yamagishi Ai Ikeda Mina Hayama-Terada Yuji Shimizu Isao Muraki Mitsumasa Umesawa Hironori Imano Tomoko Sankai Takeo Okada Akihiko Kitamura Masahiko Kiyama Hiroyasu Iso CIRCS Investigators Source Type: research