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Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases
Vasa. 2022 Oct 6. doi: 10.1024/0301-1526/a001031. Online ahead of print.ABSTRACT Vascular adhesion protein-1 (VAP-1) also known as amino oxidase copper containing 3 (AOC3) is a pro-inflammatory and versatile molecule with adhesive and enzymatic properties. VAP-1 is a primary amine oxidase belonging to the semicarbazide-sensitive amine oxidase (SSAO) family, which catalyzes the oxidation of primary amines leading to the production of ammonium, formaldehyde, methylglyoxal, and hydrogen peroxide. VAP-1 is mainly expressed by endothelial cells, smooth muscle cells, adipocytes and pericytes. It is involved in a repertoire of bi...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 6, 2022 Category: Surgery Authors: Marianna Danielli Roisin Clare Thomas Lauren Marie Quinn Bee Kang Tan Source Type: research

Carotid Intervention Improves Cognitive Function in Patients With Severe Atherosclerotic Carotid Disease
Conclusions: This prospective study showed that carotid intervention improved memory and executive function in patients with the severe carotid occlusive disease. It highlights the cognitive benefit of the carotid intervention in appropriately selected patients.
Source: Annals of Surgery - August 18, 2022 Category: Surgery Tags: Papers of the 141st ASA Annual Meeting Source Type: research

Neurologic outcomes of carotid and other emergent interventions for ischemic stroke over six years with dataset enhanced by machine learning
Current mainstays of ischemic stroke treatment include the use of thrombolysis (tissue plasminogen activator, tPA), urgent carotid endarterectomy (uCEA) or carotid artery stenting (uCAS), and mechanical endovascular reperfusion/thrombectomy (MER). Scarce data describe the presenting stroke severity and neurologic outcomes for these acute ischemic stroke interventions, alone or in combination. The authors hypothesize that patients undergoing carotid interventions experience better functional neurologic outcomes than other stroke interventions.
Source: Journal of Vascular Surgery - June 24, 2022 Category: Surgery Authors: P. Andrew Rivera, Jeffrey Burton, Aaron Hayson, Bethany Jennings, Gabriel Vidal, W.C. Sternbergh, Daniel Fort, Hernan A. Bazan Source Type: research

Neurologic outcomes of carotid and other emergent interventions for ischemic stroke over 6  years with dataset enhanced by machine learning
The current mainstays of ischemic stroke treatment include the use of thrombolysis (tissue plasminogen activator [tPA]), urgent carotid endarterectomy (uCEA) or urgent carotid artery stenting (uCAS), and mechanical endovascular reperfusion/thrombectomy (MER). Scarce data describe the presenting stroke severity and neurologic outcomes for these acute ischemic stroke interventions, alone or in combination. The authors hypothesize that patients undergoing carotid interventions experience better functional neurologic outcomes than other stroke interventions.
Source: Journal of Vascular Surgery - June 24, 2022 Category: Surgery Authors: P. Andrew Rivera, Jeffrey Burton, Aaron Hayson, Bethany Jennings, Gabriel Vidal, Waldemar C. Sternbergh, Daniel Fort, Hernan A. Bazan Source Type: research

The Relationship Between Physician and Center Case Volume on Outcomes of TransCarotid Artery Revascularization
It has been suggested that the annual hospital volume of cases may affect the number of adverse events following carotid endarterectomy (CEA). Transfemoral carotid stenting (TFCAS) was found to have an extended learning curve with an estimated minimum of 25 cases for the success of the stenting procedure. One prior study indicated that transcarotid artery revascularization (TCAR) is being performed with excellent stroke and mortality rates even in the early stages of the surgeons ’ learning curve.
Source: Journal of Vascular Surgery - May 19, 2022 Category: Surgery Authors: Nadin Elsayed, Maryam Ali Khan, Claire B. Janssen, Mahmoud B. Malas Tags: IYSC: International Young Surgeons Competition Source Type: research

Virtual Rehabilitation of Elbow Flexion Following Nerve Transfer Reconstruction for Brachial Plexus Injuries Using the Single-Joint Hybrid Assisted Limb
CONCLUSION: HAL training accelerated patients' learning to convert the original muscle function into elbow flexion following NT by replicating elbow flexion during the pre-MUP detection stage and shortening the rehabilitation time.TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.PMID:35434571 | PMC:PMC9005380 | DOI:10.1016/j.jhsg.2021.12.005
Source: Hand Surgery - April 18, 2022 Category: Surgery Authors: Kazuteru Doi Dawn Sinn Yii Chia Yasunori Hattori Sotetsu Sakamoto Source Type: research

Multimodality imaging of carotid web: A case report and literature review
CONCLUSIONS: carotid web is an under-recognized cause of ischemic stroke. It is easy to be missed or misdiagnosed. Carotid revascularization can effectively prevent recurrent stroke for patients with symptomatic carotid web. Clinicians should strength their learning and understanding of carotid web.PMID:35306924 | DOI:10.1177/17085381221084809
Source: Vascular - March 21, 2022 Category: Surgery Authors: Jie Zhang Yuzhu Yan Weikai Yao Jishuang Liu Li Cui Source Type: research

Neurologic Outcomes of Carotid and Other Emergent Interventions for Ischemic Stroke Over 6  Years With Analysis Enhanced by Machine Learning
Despite continued evolution in treatment, stroke continues to represent one of the most common and debilitating diseases patients suffer. We created a novel machine-learning natural language processing algorithm to assist in performing outcomes research for patients undergoing treatment for stroke. This method enhanced our ability to accurately determine neurologic outcomes for all urgent stroke interventions. Results demonstrate stroke severity and functional neurologic outcomes for all ischemic stroke patients undergoing (1) urgent carotid endarterectomy (uCEA)/urgent carotid artery stenting (uCAS), (2) tissue plasminoge...
Source: Journal of Vascular Surgery - December 20, 2021 Category: Surgery Authors: P. Andrew Rivera, Bethany Jennings, Jeff Burton, Aaron Hayson, Faith Mason, Jaron Pettis, Adam Berenson, W.C. Sternbergh, Samuel Money, Daniel Fort, Hernan Bazan Source Type: research

Pass On What You Have Learned: A Structured Mentor-Mentee Concept for the Implementation of a Minimally Invasive Mitral Valve Surgery Program
Conclusion: Typically, excellent exposure and high repair rates of the MV has led us offer MICS approach to a majority of patients with isolated MV disease. Careful planning and a strict mentor-mentee concept facilitated a safe startup of an MICS program in a busy university heart center.Eur Surg Res
Source: European Surgical Research - December 1, 2021 Category: Surgery Source Type: research

Establishing minimally invasive cardiac surgery in a low-volume mitral surgery centre
DISCUSSION: It is possible for low-volume cardiac surgical centres to undertake minimally invasive surgical programmes with good outcomes and short learning curves. Despite technical complexities, with a team approach, the learning curve can be navigated safely.PMID:34058117 | DOI:10.1308/rcsann.2020.7092
Source: Annals of the Royal College of Surgeons of England - May 31, 2021 Category: Surgery Authors: B H Kirmani A Knowles P Saravanan J Zacharias Source Type: research

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