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Cardiovascular disease and stroke risk assessment in patients with chronic kidney disease using integration of estimated glomerular filtration rate, ultrasonic image phenotypes, and artificial intelligence: a narrative review.
Authors: Jamthikar AD, Puvvula A, Gupta D, Johri AM, Nambi V, Khanna NN, Saba L, Mavrogeni S, Laird JR, Pareek G, Miner M, Sfikakis P, Protogerou A, Kitas GD, Nicolaides A, Sharma AM, Viswanathan V, Rathore VS, Kolluri R, Bhatt DL, Suri JS Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) together result in an enormous burden on global healthcare. The estimated glomerular filtration rate (eGFR) is a well-established biomarker of CKD and is associated with adverse cardiac events. This review highlights the link between eGFR reduction and that of atherosclerosis progression, which increases the r...
Source: International Angiology - November 27, 2020 Category: Cardiology Tags: Int Angiol Source Type: research

Global perspective on carotid intima-media thickness and plaque: should the current measurement guidelines be revisited?
Authors: Saba L, Jamthikar A, Gupta D, Khanna NN, Viskovic K, Suri HS, Gupta A, Mavrogeni S, Turk M, Laird JR, Pareek G, Miner M, Sfikakis P, Protogerou A, Kitas GD, Viswanathan V, Nicolaides A, Bhatt D, Suri JS Abstract Carotid intima-media thickness (cIMT) and carotid plaque (CP) currently act as risk predictors for CVD/Stroke risk assessment. Over 2000 articles have been published that cover either (a) use cIMT/CP or alterations of cIMT/CP and (b) additional image-based phenotypes to associate cIMT related markers with CVD/Stroke risk. These articles have shown variable results, which likely reflect a lack of st...
Source: International Angiology - December 1, 2019 Category: Cardiology Tags: Int Angiol Source Type: research

Immune cells in carotid artery plaques: what can we learn from endarterectomy specimens?
CONCLUSIONS: Since the destabilization of the atherosclerotic plaque is a multifactorial process, a combination of various methods should be used to characterize the unstable plaques more accurately. In this context, studies characterizing plaque content from a cellular point ofview could elucidate some processes underlying the plaque progression. Together with morphological evaluation, these analyses could enable more precise assessment of plaque stability. PMID: 31782285 [PubMed - as supplied by publisher]
Source: International Angiology - December 1, 2019 Category: Cardiology Tags: Int Angiol Source Type: research

Automated deep learning-based paradigm for high-risk plaque detection in B-mode common carotid ultrasound scans: an asymptomatic Japanese cohort study
CONCLUSIONS: The proposed study demonstrates a fast, accurate, and reliable solution for early detection and quantification of plaque lesions in common carotid artery ultrasound scans. The system runs on a test US image in < 1 second, proving overall performance to be clinically reliable.PMID:34825801 | DOI:10.23736/S0392-9590.21.04771-4
Source: International Angiology - November 26, 2021 Category: Cardiology Authors: Pankaj K Jain Neeraj Sharma Luca Saba Kosmas I Paraskevas Mandeep K Kalra Amer Johri Andrew N Nicolaides Jasjit S Suri Source Type: research

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