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Total 1312 results found since Jan 2013.
Timely treatment after stroke is crucial, UCLA researchers report
For years, the mantra of neurologists treating stroke victims has been "time equals brain." That's because getting a patient to the emergency room quickly to receive a drug that dissolves the stroke-causing blood clot can make a significant difference in how much brain tissue is saved or lost.
But specific information has been limited on just how the timing of giving the intravenous drug — known as a tissue plasminogen activator, or tPA — influences outcomes for victims of ischemic (clot-caused), stroke, the most common type of stroke.
Now, a team led by UCLA researchers has conducted a major stud...
Source: UCLA Newsroom: Health Sciences - June 18, 2013 Category: Universities & Medical Training Source Type: news
Hospitals in GWTG-Stroke program more likely to provide recommended stroke treatment
Timely stroke treatment is critical to ensuring good outcomes for patients. A new national study compared two programs designed to help hospitals adhere to nationally accepted standards and guideline recommendations for stroke treatment and found that hospitals participating in the Get With The Guidelines–Stroke program were more likely than Primary Stroke Center–certified hospitals to provide all the guideline-based measures of care for patients.
The study appears in the Oct. 14 issue of the Journal of the American Heart Association.
The American Heart Association/American Stroke Association's ...
Source: UCLA Newsroom: Health Sciences - October 15, 2013 Category: Universities & Medical Training Source Type: news
Stroke treatment, outcomes improve at hospitals participating in UCLA-led initiative
Administering a clot-dissolving drug to stroke victims quickly — ideally within the first 60 minutes after they arrive at a hospital emergency room — is crucial to saving their lives, preserving their brain function and reducing disability.
Given intravenously, tPA (tissue plasminogen activator) is currently the only Food and Drug Administration–approved therapy shown to improve outcomes for patients suffering acute ischemic stroke, which affects some 800,000 Americans annually.
Now, a UCLA-led study demonstrates that hospitals participating in the "Target: Stroke" national quality-improvement program have markedly...
Source: UCLA Newsroom: Health Sciences - April 23, 2014 Category: Universities & Medical Training Source Type: news
Researcher Studies Statins for Stroke Therapy
Stacy Pigott
A $2.8 million grant may help develop an improved therapeutic treatment for acute ischemic stroke patients to let them recover faster with fewer long-term complications. The protocol hinges on effectively delivering statins to the brain, where their neuroprotective properties can help save tissue damaged by stroke.
Aug. 7, 2020
University of Arizona Health Sciencesnhg-PATRICK-RONALDSON_DSC6492-web.jpg
Patrick Ronaldson (right), associate professor in the College of Medicine – Tucson's Department of Pharmacology, and doctoral students Erica Williams and Robert Betterton discuss their latest researc...
Source: The University of Arizona: Health - August 6, 2020 Category: Universities & Medical Training Authors: mittank Source Type: research
Paramedics may be best first line of defense in treating stroke patients
This study involved an unprecedented cooperative effort of paramedics in the field and emergency physicians serving as investigators,” said Dr. Sidney Starkman, co-principal investigator and co-director of the UCLA Stroke Center.
“Through this study we were able to instill permanently in everyone’s mind the idea that ‘time is brain.’ We believe this represents a paradigm shift in the treatment of stroke and potentially numerous other neurological conditions,” said Starkman, who also is professor of emergency medicine and neurology at the Geffen School. “We demonstrated that paramedics not only are eager to pr...
Source: UCLA Newsroom: Health Sciences - February 5, 2015 Category: Universities & Medical Training Source Type: news
Discovery could lead to better recovery after stroke
UCLA researchers have identified a molecule that, after a stroke, signals brain tissue to form new connections to compensate for the damage and initiate repairs to the brain.
The finding could eventually lead to a new treatment to promote brain repair and functional recovery in people who have suffered a stroke, which is the leading cause of serious long-term disability in adults.
The five-year study, performed in an animal model, was the first to identify growth differentiation factor 10, or GDF10, a molecule that previously had no known role in the adult brain, said Dr. S. Thomas Carmichael, the study’s senior author ...
Source: UCLA Newsroom: Health Sciences - October 26, 2015 Category: Universities & Medical Training Source Type: news
Quick magnesium treatment fails to improve stroke outcomes, but study has silver lining
In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of the onset of symptoms does not improve stroke outcomes.
However, the 8-year trial did find that with the help of paramedics in the field, intravenous medications can frequently be administered to stroke victims within that so-called "golden hour," during which they have the best chance to survive and avoid debilitating, long-term neurological damage.
The latter finding is a "game-changer," said Dr. Jeffrey Saver, director of the UCLA Stroke Center and a professor of ...
Source: UCLA Newsroom: Health Sciences - February 13, 2014 Category: Universities & Medical Training Source Type: news
Clot removal device dramatically improves outcomes for people with acute ischemic stroke
A new device to remove obstructing blood clots can significantly improve outcomes for people who suffer a certain type of stroke, according to a study led by a UCLA investigator.
In patients with acute ischemic stroke — in which a clot blocks the blood supply to part of the brain — who received a clot-busting drug, removing the obstructing blood clot with a stent retriever device significantly reduced post-stroke disability and increased the percentage of patients who were independent in daily function after three months.
The findings represent the first new treatment for acute ischemic stroke in 20 years, since the de...
Source: UCLA Newsroom: Health Sciences - April 17, 2015 Category: Universities & Medical Training Source Type: news
Speedy treatment of stroke patients with new clot retrieval device vastly improves outcomes
In the treatment of stroke patients, time really is brain. A few minutes can mean the difference between patients living independently or suffering debilitating disabilities.
Now, UCLA researchers have shown, for the first time, that speedy treatment with a new-generation stent clot retrieval device results in greatly improved outcomes, and that even a five-minute delay negatively affects patients.
The one-year study found that when blood flow was restored to the brain within four hours of the start of a stroke, 80 percent of patients had a very good outcome — meaning that they survived and were able to live independent...
Source: UCLA Newsroom: Health Sciences - August 17, 2015 Category: Universities & Medical Training Source Type: news
UCLA Health launches pioneering mobile stroke unit with support from L.A. County
Roughly every 40 seconds, someone in the United States will have a stroke. Almost every four minutes, one of those people will die as a result. Against that backdrop, UCLA Health has officially launched the first mobile stroke unit on the West Coast, enabling rapid delivery of brain-saving medications to stroke patients who might otherwise face debilitating delays in treatment. As part of the first phase of a pilot program, the specialized ambulance unit and highly trained personnel began responding in September to select 911 calls in Santa Monica in coordination with the Santa Monica Fire Department. With support from t...
Source: UCLA Newsroom: Health Sciences - October 26, 2017 Category: Universities & Medical Training Source Type: news
The Riga East University Hospital Stroke Registry-An Analysis of 4915 Consecutive Patients with Acute Stroke
Conclusions: Our stroke registry data are comparable to those of other major registries. Analysis of stroke registry data is important for improving stroke care and obtaining additional information for stroke studies.PMID:34207100 | DOI:10.3390/medicina57060632
Source: Medicina (Kaunas) - July 2, 2021 Category: Universities & Medical Training Authors: Guntis Karelis Madara Micule Evija Klavina Iveta Haritoncenko Ilga Kikule Biruta Tilgale Inese Polaka Source Type: research
