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Total 3962 results found since Jan 2013.

Migraine, White Matter Hyperintensities, and Subclinical Brain Infarction in a Diverse Community: The Northern Manhattan Study Brief Reports
Conclusions— Migraine may be a risk factor for subclinical brain infarction. Prospective studies are needed in race/ethnically diverse populations.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Monteith, T., Gardener, H., Rundek, T., Dong, C., Yoshita, M., Elkind, M. S. V., DeCarli, C., Sacco, R. L., Wright, C. B. Tags: Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke Brief Reports Source Type: research

Recurrent Ischemic Stroke in a Patient with the Trousseau Syndrome Treated with Dabigatran
A 70-year-old man with multiple ischemic strokes was diagnosed with cardiac embolism and treated with dabigatran. Three months later, he suddenly developed vertigo and vomiting. Magnetic resonance imaging, showed recurrent lesions and blood tests revealed hypercoagulability, hypoproteinemia, and elevated cytokeratin 19 fragments that serve as a tumor marker of lung cancer. Chest computed tomography showed there were small nodules in bilateral lungs and swollen mediastinal lymph nodes. A conclusive diagnosis was impossible because the patient declined invasive procedures. We suspected primary lung cancer and diagnosed conco...
Source: Journal of Stroke and Cerebrovascular Diseases - February 21, 2014 Category: Neurology Authors: Kosuke Yoshida, Takashi Kimura, Yoko Aburakawa, Yasuhiro Suzuki, Kenji Kuroda, Osamu Yahara Tags: Case Reports Source Type: research

Early microvascular dysfunction in cerebral small vessel disease is not detectable on 3.0 Tesla magnetic resonance imaging: a longitudinal study in spontaneously hypertensive stroke-prone rats
Conclusion Serial MRI at a field strength of 3 T failed to detect the initial microvascular dysfunction and subsequent small perivascular bleeds in SHRSP; only terminal stages of cerebral microangiopathy were reliably detected. Further investigations at higher magnetic field strengths (7 T) using blood- and flow-sensitive sequences are currently underway.
Source: Experimental and Translational Stroke Medicine - June 25, 2013 Category: Neurology Source Type: research

Using Standard First-Pass Perfusion Computed Tomographic Data to Evaluate Collateral Flow in Acute Ischemic Stroke Clinical Sciences
Conclusions— Ktrans maps extracted from standard first-pass perfusion computed tomography are correlated with collateral circulation status after acute proximal arterial occlusion and predictive of outcome.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Chen, H., Wu, B., Liu, N., Wintermark, M., Su, Z., Li, Y., Hu, J., Zhang, Y., Zhang, W., Zhu, G. Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Intravital imaging in spontaneously hypertensive stroke-prone rats-a pilot study
Conclusions Contrary to our initial expectations, there was little agreement between intravital 2 PM imaging and histology for the detection of erythrocyte thrombi. Two-photon microscopy is a valuable technique that complements but does not replace the value of conventional histology.
Source: Experimental and Translational Stroke Medicine - January 25, 2014 Category: Neurology Source Type: research

Patterns of Poststroke Brain Damage That Predict Speech Production Errors in Apraxia of Speech and Aphasia Dissociate Clinical Sciences
Conclusions— AOS likely occurs in conjunction with aphasia because of the proximity of the brain areas supporting speech and language, but the neurobiological substrate for each disorder differs.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Basilakos, A., Rorden, C., Bonilha, L., Moser, D., Fridriksson, J. Tags: Behavioral/psychosocial - stroke Clinical Sciences Source Type: research

Auditory Spatial Deficits in the Early Stage of Ischemic Cerebral Stroke
Clinical research, together with computed tomography/magnetic resonance imaging findings, proves that ischemic stroke (IS) that damages auditory pathways can cause hearing loss and impairment of higher auditory processes such as sound localization. The goal of the study was to find possible correlations between the IS risk factors, ischemic lesion volume and localization, neurologic status, and the sound localization capability in acute IS patients.
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2015 Category: Neurology Authors: Tomasz Przewoźny, Anna Gójska-Grymajło, Dariusz Gąsecki Source Type: research

White Matter Damage Relates to Oxygen Saturation in Children With Sickle Cell Anemia Without Silent Cerebral Infarcts Clinical Sciences
Conclusions— These data show widespread white matter abnormalities in a sample of asymptomatic children with sickle cell anemia, and provides for the first time direct evidence of a relationship between brain microstructure and markers of disease severity (eg, peripheral oxygen saturation and steady-state hemoglobin). This study suggests that diffusion tensor imaging metrics may serve as a biomarker for future trials of reducing hypoxic exposure.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Kawadler, J. M., Kirkham, F. J., Clayden, J. D., Hollocks, M. J., Seymour, E. L., Edey, R., Telfer, P., Robins, A., Wilkey, O., Barker, S., Cox, T. C. S., Clark, C. A. Tags: Stroke in Children and the Young Clinical Sciences Source Type: research

Therapeutically Targeting Tumor Necrosis Factor-{alpha}/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage Basic Sciences
Conclusions— Vascular smooth muscle cell TNFα and sphingosine-1-phosphate signaling significantly enhance cerebral artery tone in SAH; anti-TNFα and anti–sphingosine-1-phosphate treatment may significantly improve clinical outcome.
Source: Stroke - July 27, 2015 Category: Neurology Authors: Yagi, K., Lidington, D., Wan, H., Fares, J. C., Meissner, A., Sumiyoshi, M., Ai, J., Foltz, W. D., Nedospasov, S. A., Offermanns, S., Nagahiro, S., Macdonald, R. L., Bolz, S.-S. Tags: Animal models of human disease, Acute Cerebral Hemorrhage, Brain Circulation and Metabolism, Other Stroke Treatment - Medical, Other Vascular biology Basic Sciences Source Type: research

Prevalence and Risk Factors of Acute Incidental Infarcts Clinical Sciences
Conclusions— AII are more likely to be present in those with cognitive impairment. Although a cause–effect relationship between the presence of AII and cognitive impairment is plausible, the association may be because of under-reporting of symptoms by individuals with cognitive impairment. The association between AII and cerebral microbleeds may indicate cerebral vasculopathy, independent of traditional vascular risk factors.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Saini, M., Suministrado, M. S. P., Hilal, S., Dong, Y. H., Venketasubramanian, N., Ikram, M. K., Chen, C. Tags: Acute Stroke Syndromes Clinical Sciences Source Type: research

Association of Magnetic Resonance Imaging Markers of Cerebrovascular Disease Burden and Cognition Clinical Sciences
Conclusions— The weighted CeVD burden score comprising markers of both small- and large-vessel diseases were associated with deficits in both global and domain-specific neurocognitive function. Additional studies are needed to validate the use of this CeVD burden score for the prediction of dementia.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Xu, X., Hilal, S., Collinson, S. L., Chong, E. J. Y., Ikram, M. K., Venketasubramanian, N., Chen, C. L.-H. Tags: Cerebrovascular disease/stroke, CT and MRI Clinical Sciences Source Type: research

Letter by Gutierrez et al Regarding Article, "Differential Vascular Pathophysiologic Types of Intracranial Atherosclerotic Stroke: A High-Resolution Wall Magnetic Resonance Imaging Study" Letters to the Editor
Source: Stroke - November 23, 2015 Category: Neurology Authors: Gutierrez, J., Elkind, M. S. V., Marshall, R. S. Tags: Cerebrovascular Disease/Stroke, Atherosclerosis Letters to the Editor Source Type: research

Implementation of a Community-Based Triage for Patients with Suspected Transient Ischemic Attack or Minor Stroke Study: A Prospective Multicenter Observational Study
Japan has the highest number of magnetic resonance imaging units in the world, and citizens can freely choose medical care at any hospital or clinic. We aimed to investigate the triage of patients with suspected transient ischemic attack (TIA) or minor stroke in this unique Japanese healthcare system.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2016 Category: Neurology Authors: Hiroki Taguchi, Yasuhiro Hasegawa, Kuniaki Bandoh, Hideki Koyasu, Yuukou Watanabe, Kohei Yamashita, Kenji Shimazaki, Hiroshi Shima, Masaaki Miyakawa, Yoshikazu Niwa, COMBAT-TIA Study Investigators Source Type: research

Thrombus Length Estimation on Delayed Gadolinium-Enhanced T1 Clinical Sciences
Conclusions— The dGE-T1, obtained by simply adjusting scanning order in multimodal magnetic resonance imaging protocol, is a useful tool for thrombus length estimation and middle cerebral artery recanalization prediction after IVT.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Yan, S., Chen, Q., Xu, M., Sun, J., Liebeskind, D. S., Lou, M. Tags: Angiography, Ischemic Stroke Clinical Sciences Source Type: research

Stroke Presentation of Acute Type A Aortic Dissection with 100% Perfusion-Weighted Imaging–Diffusion-Weighted Imaging Mismatch: A Call for Urgent Action
Acute stroke in the setting of acute type A aortic dissection is not rare and may contraindicate immediate surgery. Evaluating irreversible brain damage is critical in this setting and magnetic resonance imaging is a key determinant in the decision of selecting surgical over medical treatment for these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 7, 2016 Category: Neurology Authors: Gilles Amr, Gregoire Boulouis, Nicolas Bricout, Thomas Modine, Georges Fayad, Pierre Aguettaz, Mohamad Koussa Tags: Case Studies Source Type: research