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Effects of vitamin E on neurodegenerative diseases: an update
Acta Neurobiol Exp (Wars). 2021;81(1):21-33. doi: 10.21307/ane-2021-003.ABSTRACTVitamin E deficiency is associated with many neurological problems. Although the mechanisms of vitamin E action in neurodegenerative diseases are not clear, there are many possible mechanisms. Examples of such mechanisms are the protective effects of vitamin E against oxidative stress damage and its suppressive role in the expression of many genes involved in the development of neurodegeneration. Many studies have evaluated the relationship between vitamin E intake or vitamin E levels in body fluids and neurodegenerative diseases. Some studies ...
Source: Acta Neurobiologiae Experimentalis - May 5, 2021 Category: Neurology Authors: Mehmet Arif Icer Neslihan Arslan Makbule Gezmen-Karadag Source Type: research

Neuroprotective Effects of Tocovid Pretreatment in a Mouse Stroke Model
Tocovid is a new combination of tocotrienols and tocopherol, both of which are neuroprotective agents for preventing cerebral infarction in mice. However, the effects of tocovid on anti-inflammation in ischemic model remain elusive. In the present study, we assessed the effects of Tocovid pretreatment on anti-inflammatory effects after transient middle cerebral occlusion (tMCAO) in mice.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2018 Category: Neurology Authors: Yang Jiao, Jingwei Shang, Yasuyuki Ohta, Hongjing Yan, Xia Liu, Xianghong Li, Ryuta Morihara, Yumiko Nakano, Yusuke Fukui, Xiaowen Shi, Yong Huang, Tian Feng, Mami Takemoto, Kota Sato, Nozomi Hishikawa, Toru Yamashita, Koji Abe Source Type: research

Therapeutic Effects of Pretreatment with Tocovid on Oxidative Stress in Postischemic Mice Brain
Dietary supplement is an attempt to reduce the risk of ischemic stroke in high-risk population. A new mixed vitamin E-Tocovid that mainly contains tocotrienols other than tocopherol, attenuated the progression of white matter lesions by oral in humans. However, the effect of Tocovid on ischemic stroke has not been examined. In the present study, we assessed the therapeutic effects of Tocovid pretreatment on transient middle cerebral artery occlusion (tMCAO) in mice.
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2018 Category: Neurology Authors: Jingwei Shang, Hongjing Yan, Yang Jiao, Yasuyuki Ohta, Xia Liu, Xianghong Li, Ryuta Morihara, Yumiko Nakano, Yusuke Fukui, Xiaowen Shi, Yong Huang, Tian Feng, Mami Takemoto, Kota Sato, Nozomi Hishikawa, Toru Yamashita, Koji Abe Source Type: research

Current Treatment Options: Headache Related to Menopause —Diagnosis and Management
AbstractPurpose of reviewMenopause is a life-changing event in numerous ways. Many women with migraine hold hope that the transition to the climacteric state will coincide with a cessation or improvement of migraine. This assumption is based mainly on common lay perceptions as well as assertions from many in the healthcare community. Unfortunately, evidence suggests this is far from the rule. Many women turn to a general practitioner or a headache specialist for prognosis and management. A natural instinct is to manipulate the offending agent, but in some cases, this approach backfires, or the concern for adverse events ou...
Source: Current Treatment Options in Neurology - March 6, 2018 Category: Neurology Source Type: research

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