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P067/132 Cerebral vasospasm treatment using comaneci device - registry study
ConclusionThe Comaneci device has the potential to serve as a first-line device for providing therapeutic benefit to patients with SAH and vasospasm. However, future prospective trials are required.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Hensler, J., Larsen, N., Christian, R., Nordmeyer, H., Breyer, T., Hesselmann, V., Jan, H., Jansen, O. Tags: 1.1 HAEMORRHAGIC - Aneurysms Source Type: research

P114/135 Drug-coated balloons for treatment of in-stent restenosis following carotid artery stenting: a major case, single center study
ConclusionIn our practice, DCB offers a straightforward option to treat restenosis of the ACI ostium. The low rate of periprocedural complications and the median time of freedom from symptoms and/or restenosis suggest that DCB angioplasty for ISRS is a viable treatment.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Hajiyev, K., Gottberg, P. v., Henkes, H. Tags: 3.1 OTHER - Innovation Source Type: research

P165/237 Development and Validation of a novel stenosis model for percutaneous transluminal angioplasty training
ConclusionThe authors propose a novel ICA stenosis simulation model for training of PTA.The model provides a realistic and replicable method for standardized procedural training.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Ramdani, N., Anna, K., Tuan, N., Jonte, S., Dieter, K., Fabian, F., Lukas, M., Jens, F., Maxim, B., Helena, G. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

O06/60 Diagnosis of intracranial atherosclerosis related large vessel occlusion before endovascular treatment
ConclusionA combination of clinical and radiological variables available before EVT can accurately predict the presence of an ICAD-LVO. The ICAD-Scale could be useful to perform a rapid assessment of underlying etiology and suggest specific pathophysiology-based measures (adjunctive pharmacological treatment, angioplasty and/or intracranial stenting).Disclosure of InterestDr Molina reported receiving personal fees from AstraZeneca for consultant services outside the submitted work. Dr Tomasello reported receiving personal fees from Anaconda Biomed, Balt, Medtronic, Perflow, and Stryker outside the submitted work. Dr Ribo r...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Rodrigo-Gisbert, M., Garcia-Tornel, A., Requena, M., Rubiera, M., Lascuevas, M. D. D., Olive, M., Pinana, C., Rizzo, F., Muchada, M., Rodriguez-Villatoro, N., Rodriguez-Luna, D., Juega, J., Pagola, J., Hernandez, D., Molina, C. A., Tomasello, A., Ribo, M. Tags: 2.2 ISCHEMIC - Imaging Source Type: research

Retained radial catheters associated with variant radial anatomy in neurointerventional procedures
Conclusion Retained catheters for neurointerventional procedures performed via TRA are rare. However, this complication may be associated with variant radial anatomy. With the increased use of TRA for neurointerventional procedures, awareness of anatomical abnormalities that may lead to a retained catheter is necessary. We propose a simple protocol to avoid catheter entrapment, including in emergent situations such as TRA for stroke thrombectomy.
Source: Journal of NeuroInterventional Surgery - August 17, 2023 Category: Neurosurgery Authors: Catapano, J. S., Winkler, E. A., Srinivasan, V. M., Dishion, E. L., Rutledge, C., Baranoski, J. F., Cole, T. S., Rudy, R. F., Rumalla, K., Zomaya, M. P., Jadhav, A. P., Ducruet, A. F., Albuquerque, F. C. Tags: New devices New devices and techniques Source Type: research

E-098 Initial experience with the pipeline vantage flow diverter - vantage one study: six-month results, technical and clinical consideration
ConclusionThe new PVED reveals improved device visibility, ease of delivery and repositioning with precise distal opening in comparison to previous PED generations. Initial results demonstrate overall good device performance, safety profile and effectiveness. The implant requires a modified deployment technique for successful vessel wall apposition of the proximal stent as opposed to the previous generations of PED.ReferencesLylyk I, Scrivano E, Lundquist J, Ferrario A, Bleise C, Perez N, Lylyk PN, Viso R, Nella-Castro R, Lylyk P. Pipeline embolization devices for the treatment of intracranial aneurysms, single-center regi...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: de Viliers, L., Carraro do Nascimento, V., Domitrovic, L., Rice, H. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

O-002 Safety and functional outcomes with early initiation of antiplatelet therapy following mechanical thrombectomy in emergent large vessel occlusion strokes: a single institution registry study
ConclusionsEarly AP initiation after MT in patients with AIS due to LVO was independently associated with significantly increased odds of better postoperative functional outcomes without increased odds of developing HT.Abstract O-002 Table 1Safety, clinical and functional outcomes: univariable analysis N=190 Early (<24 hours) (n=95) Late (>24 hours) (n=95) p-value Hemorrhagic TransformationSymptomaticAsymptomaticInpatient Mortality 25 (26.3)3 (3.2)22 (23.2)16 (16.8) 21 (22.1)8 (8.4)13 (13.7)23 (24.2) 0.4980.1200.0920.281 Discharge Modified Rankin Score*Functional Independence 4 (0-6)29 (30.5) 5 (0-6)14 (14.7) <.0...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Alexander, H., Claus, C., Tong, D., Kelkar, P., Griauzde, J., Teck, S., Richards, B. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-004 A propensity score-matched comparative study of balloon guide catheters vs conventional guide catheters for mechanical thrombectomy with stenting in tandem strokes: comparison of 1st-pass effect, symptomatic ICH, and 90-day functional outcomes
ConclusionBGCs used for concurrent MT-carotid revascularization with flow arrest were safe and resulted in superior clinical and angiographic outcomes in tandem stroke patients.Abstract O-004 Table 1Multivariate logistic regression analysis performed after propensity score matching to compare procedural parameters and angiographic and clinical outcomes between balloon guide catheter and conventional guide catheter groupsDisclosures A. Baig: None. M. Waqas: None. R. Turner: None. C. Kuo: None. B. Donnelly: None. P. Lai: None. K. Raygor: None. M. Bouslama: None. J. Lim: None. J. Neumaier: None. J. Cappuzzo: None. J. Davies: ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Baig, A., Waqas, M., Turner, R., Kuo, C., Donnelly, B., Lai, P., Raygor, K., Bouslama, M., Lim, J., Neumaier, J., Cappuzzo, J., Davies, J., Snyder, K., Siddiqui, A., Levy, E. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-005 Submaximal angioplasty alone vs. stenting plus angioplasty for symptomatic intracranial atherosclerotic disease - a propensity score matched comparative study with long term follow-up
ConclusionSubmaximal angioplasty alone results in better long-term clinical outcomes in terms of stroke/TIA when compared with stenting and angioplasty for symptomatic intracranial atherosclerotic disease, and represents a potentially promising intervention.Abstract O-005 Table 1Procedural outcomes and patient follow-up dichotomized by submaximal angioplasv vs. stenting and angioplasty after propensity score matchingDisclosures A. Baig: None. A. Aguirre: None. B. Donnelly: None. C. Kuo: None. M. Kruk: None. J. Im: None. N. Joseph: None. C. Palka: None. A. Maini: None. E. Hashmi: None. J. Lim: None. R. Turner: None. P. Lai:...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Baig, A., Aguirre, A., Donnelly, B., Kuo, C., Kruk, M., Im, J., Joseph, N., Palka, C., Maini, A., Hashmi, E., Lim, J., Turner, R., Lai, P., Raygor, K., Siddiqui, A., Levy, E. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-035 Endovascular treatment of cerebral venous thrombosis involving the deep venous system
ConclusionsAlthough deep venous involvement of CVT is uncommon, these patients are at risk of quickly becoming critically ill with an elevated rate of death or dependency. Although these patients may develop stroke, hemorrhage, or neurologic decline prompting consideration of endovascular therapy, the deep cerebral venous system is not easily accessible with catheters due to small lumens and risk of perforation. It has been proposed that deep cerebral veins may have a higher chance of recanalization if venous thrombus burden is reduced in other parts of the dural venous sinuses. Current literature has not fully explored th...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Morel, B., Hoffman, J., Folzenlogen, Z., Roark, C., Seinfeld, J., Case, D. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-063 First U.S. multicenter experience using the pipeline flex embolization device with shield technology for treatment of intracranial aneurysms
ConclusionOur study is the first to report the early experience with the newly FDA-approved PED Flex with Shield technology amongst US centers. Our results are comparable with non-US, international studies showing a high technical success rate and safe peri-procedural angiographic and patient outcome. Longer follow-up will be needed to provide more robust data on angiographic and patient outcomes.Disclosures A. Kuhn: None. J. Singh: None. A. Abdelsalam: None. V. Saini: None. J. Burks: None. G. Cortez: None. R. Abbas: None. M. Pervez: None. H. Saei: None. S. Burke: None. M. Salem: None. J. Vivanco-Suarez: None. R. Kutcher-D...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kuhn, A., Singh, J., Abdelsalam, A., Saini, V., Burks, J., Cortez, G., Abbas, R., Pervez, M., Saei, H., Burke, S., Salem, M., Vivanco-Suarez, J., Kutcher-Diaz, R., Bounajem, M., Naragum, V., Massari, F., Marwah, S., Gounis, M., Hassan, A., Malek, A., Dabu Tags: SNIS 20th annual meeting oral abstracts Source Type: research

E-248 Rescue intracranial stenting for failed posterior circulation thrombectomy: analysis from saint study
ConclusionIn patients with posterior circulation occlusion stokes who failed mechanical thrombectomy, our study suggests that RS has better outcomes with comparable safety profile. Randomized controlled studies are warranted for more concrete evidence.Abstract E-248 Table 1Baseline demographic, clinical and procedural characteristics among rescue stenting and failed reperfusion groups Rescue stentingN=84 Failed ReperfusionN=68 P value Age 63.6±12.6 69.7±13.5 0.005 Female 18 (21.4%) 35 (51.5%) <0.001 Ethnic BackgroundWhiteAAHispanicAsianOthers 33 (39.3%)20 (23.8%)22 (26.2%)4 (4.8%)5 (6%) 34 (50%)22 (32.4%)...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Mohammaden, M., Tarek, M., Haussen, D., Fifi, J., Matsoukas, S., Farooqui, M., Ortega-Gutierrez, S., Zevallos, C., Galecio-Castillo, M., Hassan, A., Tekle, W., Al-Bayati, A., Salem, M., Burkhardt, J., Pukenas, B., Cortez, G., Hanel, R., Aghaebrahim, A., S Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-061 Glycoprotein inhibitors as a standalone post-thrombectomy rescue treatment for intracranial atherosclerotic disease-related stroke: a systematic review and meta-analysis
ConclusionThese findings highlight the potential value of GPIs as a viable first line therapy for EVT rescue therapy in the setting of ICAD. This study was limited by the nature of the literature, which were non-randomized observational studies. Randomized controlled trials are needed to validate and refine our understanding of the role of GPIs in the management of refractory or re-occlusive ICAD stroke.Disclosures A. Brake: None. C. Heskett: None. K. Le: None. L. Fry: None. M. Abraham: 2; C; Stryker.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brake, A., Heskett, C., Le, K., Fry, L., Abraham, M. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Predictors of parenchymal hemorrhage after endovascular treatment in acute ischemic stroke: data from ANGEL-ACT Registry
Conclusions In Chinese patients with AIS caused by anterior circulation LVO, the risk of PH was positively associated with low admission ASPECTS, serum glucose >7 mmol/L, and NLR, but negatively related to underlying ICAS and intracranial angioplasty/stenting. Trial registration number NCT03370939.
Source: Journal of NeuroInterventional Surgery - December 14, 2022 Category: Neurosurgery Authors: Sun, D., Jia, B., Tong, X., Kan, P., Huo, X., Wang, A., Raynald, , Ma, G., Ma, N., Gao, F., Mo, D., Song, L., Sun, X., Liu, L., Deng, Y., Li, X., Wang, B., Luo, G., Wang, Y., Ren, Z., Miao, Z., on behalf of ANGEL-ACT study group, Miao, Gui, Peng, Wu, Zha Tags: Ischemic stroke Source Type: research

First clinical multicenter experience with the new Pipeline Vantage flow diverter
Conclusions The new PV FD is safe and feasible for the treatment of intracranial aneurysms. The short-term occlusion rates are promising but need further assessment in prospective long-term follow-up studies.
Source: Journal of NeuroInterventional Surgery - December 14, 2022 Category: Neurosurgery Authors: Vollherbst, D. F., Cekirge, H. S., Saatci, I., Baltacioglu, F., Onal, B., Koc, O., Rautio, R., Sinisalo, M., Tomasello, A., Vega, P., Martinez-Galdamez, M., Lynch, J., Mendes Pereira, V., Bendszus, M., Möhlenbruch, M. A. Tags: New devices New devices and techniques Source Type: research

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