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Specialty: Neurology
Source: Journal of Stroke and Cerebrovascular Diseases
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Total 3074 results found since Jan 2013.

The Predictive Accuracy of the Delayed Spot Sign for Haematoma Expansion in Spontaneous Supratentorial Intracerebral Haemorrhage: A Systematic Review and Meta-Analysis
Previous studies have shown that spot signs on imaging modalities such as CT perfusion, delayed phase CTA or post contrast CT imaging reportedly have greater ability to predict haematoma expansion (HE) than the traditional CT angiography spot sign. We performed a systematic review and meta-analysis of the diagnostic accuracy of the spot sign on delayed imaging modalities in predicting haematoma expansion.Pubmed, Excerpta Medica Database, and the Cochrane library were searched on the 11 November 2019.
Source: Journal of Stroke and Cerebrovascular Diseases - February 18, 2022 Category: Neurology Authors: Christopher Dillon Ovenden, Abhiram Hiwase, Aye-Aye Gyi, Amal Abou-Hamden, Timothy Kleinig Source Type: research

Dose-response Rehabilitation Organized By Pror In Out-patients With Chronic Cerebrovascular Disorder: A single-center retrospective cohort study
We aimed to investigate whether out-patient rehabilitation with the same concept as physiatrist and registered therapist operating rehabilitation (PROr) would improve activities of daily living in out-patients with chronic cerebrovascular disorder and whether the improvements were related to the frequency and/or time of therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - February 18, 2022 Category: Neurology Authors: Rikito Zaiki, Yoshi-ichiro Kamijo, Takashi Moriki, Yasunori Umemoto, Yuki Mukai, Yukio Mikami, Ken Kouda, Takahiro Ogawa, Yukihide Nishimura, Fumihiro Tajima Source Type: research

A Magnetic Resonance Angiography-Based Study Comparing Machine Learning and Clinical Evaluation: Screening Intracranial Regions Associated with the Hemorrhagic Stroke of Adult Moyamoya Disease
Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease characterized by bilateral progressive steno-occlusive changes of unknown etiology at the distal portion of the internal carotid artery or proximal portion of the anterior arteries and middle cerebral arteries, accompanied by the presence of an abnormal vessel network (moyamoya vessels) at the base of the brain.1 The incidence and prevalence of MMD are increasing worldwide, which may indicate an increase in the number of MMD patients or an underestimation of the actual number of MMD patients in the past.
Source: Journal of Stroke and Cerebrovascular Diseases - February 17, 2022 Category: Neurology Authors: Hao-lin Yin, Yu Jiang, Wen-jun Huang, Shi-hong Li, Guang-wu Lin Source Type: research

Histological composition of retrieved emboli in acute ischemic stroke is independent of pre-thrombectomy alteplase use
Given recent evidence suggesting the clot composition may be associated with revascularization outcomes and stroke etiology, clot composition research has been a topic of growing interest. It is currently unclear what effect, if any, pre-thrombectomy thrombolysis has on clot composition. Understanding this association is important as it is a potential confounding variable in clot composition research. We retrospectively evaluated the composition of retrieved clots from ischemic stroke patients who did and did not receive pre-treatment tPA to study the effect of tPA on clot composition.
Source: Journal of Stroke and Cerebrovascular Diseases - February 17, 2022 Category: Neurology Authors: Waleed Brinjikji, Mehdi Abbasi, Oana Madalina Mereuta, Se án Fitzgerald, Jorge Arturo Larco, Daying Dai, Ramanathan Kadirvel, Raul G. Nogueira, Peter Kvamme, Kennith F. Layton, Josser E. Delgado, Ricardo A. Hanel, Vitor M. Pereira, Mohammed A. Almekhlafi Source Type: research

Dynamic Changes in Brain Iron Metabolism in Neonatal Rats after Hypoxia-Ischemia
The pathogenesis of hypoxic-ischemic white matter injury (WMI) in premature infants is still unclear, and the imbalance of cerebral iron metabolism may play an important role. Our study set out to investigate the changes in iron distribution, iron content and malondialdehyde (MDA) in disparate brain regions (parietal cortex, corpus callosum, hippocampus) within 84 days after hypoxia-ischemia (HI) in neonatal rats and to clarify the role of iron metabolism in WMI.
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2022 Category: Neurology Authors: Ding-Wang Hu, Geng Zhang, Ling Lin, Xuan-Jing Yu, Feng Wang, Qing Lin Source Type: research

Initial Experience with Left Transradial Neurointerventions for Cerebral Aneurysms Using the 6-French Simmons Guiding Sheath
The use of a transradial approach utilizing a Simmons-shaped catheter for neurointervention has been steadily increasing. Although the right radial artery is commonly used, in interventional cardiology, the left transradial approach offers clear clinical benefits for right-handed patients. To the best of our knowledge, no previous studies have examined intracranial aneurysm embolization with the routine use of the left transradial approach. The aim of this study was to evaluate the technical feasibility of left transradial intracranial aneurysm embolization.
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2022 Category: Neurology Authors: Masashi Uchida, Hidemichi Ito, Hiroshi Takasuna, Tetsuya Goto, Ichiro Takumi, Takayuki Fukano, Yuta Hagiwara, Yuichiro Tanaka Source Type: research

Tideglusib Ameliorates Ischemia/Reperfusion Damage by Inhibiting GSK-3 β and Apoptosis in Rat Model of Ischemic Stroke
In this study, tideglusib, a selective irreversible and non-ATP competitive inhibitor of GSK-3β, was explored in cerebral I/R dam age using middle cerebral artery occlusion (MCAo) model in rats.
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2022 Category: Neurology Authors: Balu Joshi, Devendra Singh, Himika Wasan, Uma Sharma, KH Reeta Source Type: research

Quantitative Ischemic Characteristics and Prognostic Analysis of Crossed Cerebellar Diaschisis in Hyperacute Ischemic Stroke
This study aimed to investigate the correlation between the quantitative data of initial supratentorial ischemia and CCD, and to further explore the prognosis value of CCD in the hyperacute phase.
Source: Journal of Stroke and Cerebrovascular Diseases - February 8, 2022 Category: Neurology Authors: Weijian Chen, Shenping He, Haolan Song, Han Sun, Fancy Wang, Zhouli Tan, Yaoyao Yu Source Type: research

Transition in Incidence Rate of Hospitalised Stroke and Case Fatality Rate in the Hunter Region, Australia, 2001-2019: A Prospective Hospital-Based Study
Introduction: Continuous surveillance of stroke admissions has been conducted in the Hunter region, Australia, over the past two decades. We aimed to describe the trends in incidence rates of hospitalised stroke and case-fatality rates in this region, 2001-2019. Methods: From a hospital-based stroke registry, data for admitted adult stroke patients residing in the Hunter region were collected using ICD-10 codes for ischemic and haemorrhagic stroke. Negative binomial regression and logistic regression analysis were used to analyse trends for age-standardised and age-specific incidence rates of hospitalised stroke and 28-day...
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2022 Category: Neurology Authors: Yumi Tomari Kashida, Thomas Lillicrap, Rhonda Walker, Elizabeth Holliday, Md Golam Hasnain, Shinya Tomari, Carlos Garcia-Esperon, Jennifer J. Majersik, Neil J. Spratt, Christopher Levi Source Type: research

Safety of Antithrombotic Resumption in Chronic Subdural Hematoma Patients with Middle Meningeal Artery Embolization: A Case Control Study
Chronic subdural hematoma (CSDH) is a serious problem with an incidence of 20.6/100,000/year in North America and is posited to grow as the population ages. Middle Meningeal Artery (MMA) embolization is an upcoming therapy for treatment of CSDH. Among patients with CSDH who undergo MMA embolization outcomes are no different in patients who resume the antithrombotic (AT) after MMA embolization as compared to patients who don't resume AT.
Source: Journal of Stroke and Cerebrovascular Diseases - February 1, 2022 Category: Neurology Authors: Osman Mir, Shadi Yaghi, Deep Pujara, Jan-Karl Burkhardt, Peter Kan, Maksim Shapiro, Eytan Raz, Howard Riina, Omar Tanweer Source Type: research

Taking the Obesity Paradox to New Heights in Cerebral Atherosclerosis
Obesity typically worsens many of the major cardiovascular disease (CVD) risk factors, such as elevating blood pressure, worsening dyslipidemia, increasing impaired plasma glucose metabolism (leading to metabolic syndrome and diabetes mellitus), and increasing systemic inflammation, increasing the risk of most CVD, including hypertension, coronary heart disease (CHD), heart failure, atrial fibrillation and cerebrovascular diseases.1 –3 However, in patients with established CVD, many studies published by my colleagues and I and others have demonstrated a consistent paradox, where obese patients with established CVD seem t...
Source: Journal of Stroke and Cerebrovascular Diseases - February 1, 2022 Category: Neurology Authors: Carl J. Lavie, Salvatore Carbone, Ian J. Neeland Tags: Editorial Source Type: research

Global Metabolomic Profiling Reveals Disrupted Lipid and Amino Acid Metabolism Between the Acute and Chronic Stages of Ischemic Stroke
Stroke is a major cause of serious disability in the United States. Previous studies found multiple associations of serum metabolites with acute ischemic stroke (AIS) compared to controls, but few of them evaluated metabolome in a longitudinal fashion. Therefore, we compared the metabolome of the acute and chronic stages of ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 29, 2022 Category: Neurology Authors: Evgeny V. Sidorov, Chao Xu, Jonathan Garcia-Ramiu, Apple Blair, Jorge Ortiz-Garcia, David Gordon, Juliane Chainakul, Dharambir K. Sanghera Source Type: research

Validation of Score to Detect Intracranial Lesions in Unconscious Patients in Prehospital Setting
In this study we aimed to validate the score in a larger, separate population.
Source: Journal of Stroke and Cerebrovascular Diseases - January 29, 2022 Category: Neurology Authors: Roope Sepponen, Anssi Saviluoto, Helena J äntti, Heini Harve-Rytsälä, Mitja Lääperi, Jouni Nurmi Source Type: research

Mechanical Thrombectomy Quality Indicators Study in Czech Stroke Centers: Results of the METRICS Study
Rigorous and regular evaluation of defined quality indicators is crucial for further improvement of both technical and clinical results after mechanical thrombectomy (MT) for acute ischemic stroke (AIS). Following the recent international multi-society consensus quality indicators, we aimed to assess trend in these indicators on national level.
Source: Journal of Stroke and Cerebrovascular Diseases - January 29, 2022 Category: Neurology Authors: Martin K öcher, Daniel Šaňák, Jana Zapletalová, Filip Cihlář, Daniel Czerny, David Černík, Petr Duras, Jan Fiksa, Jakub Hustý, Lubomír Jurák, Martin Kovář, Jiří Lacman, Radek Pádr, Pavel Procházka, Jan Raupach, Martin Reiser, Vladimír R Source Type: research

Posterior Circulation Stroke: Coma (More Than Time) is Brain
When it comes to finding clinical and radiological surrogates, there's been a lot of progress in strokes from the anterior circulation. The same may not be said about posterior circulation strokes, where outcomes are actually worse.1 Scores like the National Institutes of Health Stroke Scale (NIHSS) and the Alberta Stroke Programme Early CT Score for the posterior circulation (pc-ASPECTS), have proven to be underwhelming in predicting outcomes, with studies often establishing different cutoff values.
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2022 Category: Neurology Authors: Hugo Mota D ória, Gonçalo Videira, Daniel Ferreira, Pedro Castro, Luís Albuquerque, João Pedro Filipe, Rui Felgueiras, José Pedro Rocha Pereira, Maria Luís Ribeiro, Viriato Alves, João Xavier, Denis Gabriel, Ângelo Carneiro Source Type: research