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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 3074 results found since Jan 2013.

Prevalence and Clinical Features of Asymptomatic Peripheral Artery Disease in Japanese Stroke Patients
Background: A recent worldwide disease registration study has revealed a high prevalence of polyvascular diseases in stroke patients. However, although a poor clinical outcome of patients with polyvascular disease has been reported, there have been few reports on clinical features of peripheral artery disease (PAD) in stroke patients. We assessed the prevalence, demographics, characteristics, and risk factors of PAD in Japanese stroke patients.Methods: One hundred and one consecutive chronic stroke patients in an outpatient clinic underwent ankle-brachial index (ABI) screening tests. PAD was diagnosed when the ABI was
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2011 Category: Neurology Authors: Haruhiko Hoshino, Yoshiaki Itoh, Satoshi Yamada, Norihiro Suzuki Tags: Original Articles Source Type: research

Stroke Outcomes of Japanese Patients With Major Cerebral Artery Occlusion in the Post-Alteplase, Pre-MERCI Era
This study examined outcomes of patients with acute ischemic stroke (AIS) with major cerebral artery occlusion after the approval of intravenous recombinant tissue-type plasminogen activator (IV rt-PA) but before approval of the MERCI retriever. We retrospectively enrolled 1170 consecutive patients with AIS and major cerebral artery occlusion (496 women; mean age, 73.9 ± 12.3 years) who were admitted within 24 hours after the onset of symptoms to 12 Japanese stroke centers between October 2005 and June 2009. Cardioembolism was a leading cause of AIS in this group (68.2%). The occlusion sites of the major cerebral arteries...
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2012 Category: Neurology Authors: Kaoru Endo, Masatoshi Koga, Nobuyuki Sakai, Hiroshi Yamagami, Eisuke Furui, Yasushi Matsumoto, Yoshiaki Shiokawa, Shinichi Yoshimura, Yasushi Okada, Jyoji Nakagawara, Toshio Hyogo, Yasuhiro Hasegawa, Hisashi Nagashima, Toshiyuki Fujinaka, Akio Hyodo, Tomo Tags: Original Articles Source Type: research

Ischemic Stroke and Patent Foramen Ovale: Risk Factors and Genetic Profile
Conclusions: We found that F2, which previously has been described as being a possible link between PFO and ICVD, was significantly associated with ICVD and PFO. There was also a trend toward an association between 2 other polymorphisms in the APO-CIII gene and PFO and ICVD.
Source: Journal of Stroke and Cerebrovascular Diseases - July 12, 2012 Category: Neurology Authors: Maria Lantz, Christina Sjöstrand, Konstantinos Kostulas Tags: Original Articles Source Type: research

Factors Associated with Prognosis of Eating and Swallowing Disability after Stroke: A Study from a Community-based Stroke Care System
Conclusions: Age, FIM gain, and FIM efficacy in the acute care hospital reliably predicted the long-term prognosis of eating and swallowing disability.
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2013 Category: Neurology Authors: Shinichiro Maeshima, Aiko Osawa, Takeshi Hayashi, Norio Tanahashi Tags: Original Articles Source Type: research

Intravenous Alteplase at 0.6 mg/kg for Acute Stroke Patients with Basilar Artery Occlusion: The Stroke Acute Management with Urgent Risk Factor Assessment and Improvement (SAMURAI) Recombinant Tissue Plasminogen Activator Registry
Conclusions: The use of low-dose alteplase resulted in similar outcomes when comparing acute BAO and MCO patients.
Source: Journal of Stroke and Cerebrovascular Diseases - October 12, 2012 Category: Neurology Authors: Tetsuya Miyagi, Masatoshi Koga, Yoshiaki Shiokawa, Jyoji Nakagawara, Yasuhiro Hasegawa, Eisuke Furui, Kazumi Kimura, Kazuomi Kario, Satoshi Okuda, Hiroshi Yamagami, Yasushi Okada, Tomohisa Nezu, Koichiro Maeda, Kaoru Endo, Kazuo Minematsu, Kazunori Toyoda Tags: Original Articles Source Type: research

Higher On-admission Serum Triglycerides Predict Less Severe Disability and Lower All-cause Mortality after Acute Ischemic Stroke
Conclusions: These data suggest that higher fasting TGs on-admission predict less severe disability, reduced disability progression, and all-cause mortality in patients with acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2012 Category: Neurology Authors: Slaven Pikija, Vladimir Trkulja, Lucija Juvan, Marija Ivanec, Dunja Dukši Tags: Original Articles Source Type: research

Trends in the Incidence of Stroke and Cardiovascular Risk Factors on the Isolated Island of Okinawa: The Miyakojima Study
Conclusions: In Miyakojima, the incidence of first-time stroke and all of its subtypes did not change significantly between two periods, even though blood pressure decreased significantly in the second period. Metabolic deterioration may be associated with the upward trend in incidence of brain infarction.
Source: Journal of Stroke and Cerebrovascular Diseases - November 5, 2012 Category: Neurology Authors: Chikako Sugama, Katsunori Isa, Koichiro Okumura, Kunitoshi Iseki, Kozen Kinjo, Yusuke Ohya Tags: Original Articles Source Type: research

Cognitive Dysfunction in Stroke Survivors: A Community-Based Prospective Study from Kolkata, India
The frequency of cognitive dysfunction among community stroke survivors (SS) is not known in India. This prospective study investigated the prevalence of poststroke mild cognitive impairment (psMCI) and poststroke dementia (psDem), the annual progression rate to dementia, and pertinent risk factors in a sample population of SS in Kolkata, India between September 2006 and July 2010. From a community-based stroke registry, 281 SS were assessed at baseline year after excluding attrition due to various causes. Validated cognitive tools were applied by trained field workers under supervision of a neuropsychologist. The assessme...
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2012 Category: Neurology Authors: Sujata Das, Neelanjana Paul, Avijit Hazra, Malay Ghosal, Biman Kanti Ray, Tapas Kumar Banerjee, Prabir Burman, Shyamal Kumar Das Tags: Original Articles Source Type: research

Warfarin versus Aspirin for Prevention of Stroke in Heart Failure: A Meta-analysis of Randomized Controlled Clinical Trials
Conclusions: Compared with aspirin, warfarin reduced the risk of stroke while conferring an increased risk of major hemorrhage. Warfarin does not increase mortality or confer an increased risk of ICH compared with aspirin.
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2012 Category: Neurology Authors: Gyanendra Kumar, Munish Kumar Goyal Tags: Original Articles Source Type: research

Prevalence of Fabry Disease in Young Patients with Cryptogenic Ischemic Stroke
Background: A German study diagnosed 4% of young cryptogenic ischemic stroke patients with Fabry disease, an X-linked lysosomal storage disease caused by mutations in the alpha-galactosidase A (α-GAL-A) gene resulting in an accumulation of glycosphingolipids. A lower prevalence was found in other geographic regions.Aim: To determine the prevalence of Fabry disease in a Canadian population of young cryptogenic ischemic stroke patients.Materials and Methods: Patients with cryptogenic ischemic stroke at age 16-55 were retrospectively identified in our institutional stroke database and underwent a focused clinical evaluation....
Source: Journal of Stroke and Cerebrovascular Diseases - November 19, 2012 Category: Neurology Authors: Véronique Dubuc, David F. Moore, Laura C. Gioia, Gustavo Saposnik, Daniel Selchen, Sylvain Lanthier Tags: Original Articles Source Type: research

Decompressive Hemicraniectomy for Malignant Hemispheric Stroke in the Elderly: Comparison of Outcomes between Individuals 61-70 and >70 Years of Age
Conclusions: We suggest that the efficacy of DHC in malignant hemispheric stroke patients between 61 and 70 years of age be further investigated in future randomized trials. By contrast, it appears unlikely that patients>70 years of age would benefit from DHC.
Source: Journal of Stroke and Cerebrovascular Diseases - March 13, 2013 Category: Neurology Authors: Joji Inamasu, Takafumi Kaito, Takeya Watabe, Tsukasa Ganaha, Yasuhiro Yamada, Teppei Tanaka, Shuei Imizu, Takuro Hayashi, Motoharu Hayakawa, Yoko Kato, Yuichi Hirose Tags: Original Articles Source Type: research

Patent Foramen Ovale and Infarct Volume in Cryptogenic Stroke
Background: The causal relationship between patent foramen ovale (PFO) and stroke is controversial. We hypothesized that if PFO is a pathway of embolic source, there might be a correlation between PFO characteristics (ie, size or extent of shunt) and ischemic lesion burden (ie, infarct volume and number).Methods: From ischemic stroke patients admitted to Asan Medical Center between January 2000 and October 2007, we identified those who had (1) acute ischemic lesion on diffusion-weighted imaging within 5 days of symptom onset and (2) cryptogenic stroke and only PFO detected by transesophageal echocardiography. PFO characte...
Source: Journal of Stroke and Cerebrovascular Diseases - June 7, 2013 Category: Neurology Authors: Jin-Man Jung, Jong-Young Lee, Hye-Jin Kim, Youngrok Do, Sun U. Kwon, Jong S. Kim, Jae-Kwan Song, Dong-Wha Kang Tags: Original Articles Source Type: research

“Aspirin Resistance” in Ischemic Stroke: Insights Using Short Thrombelastography
Conclusion: This study demonstrates that although COX-1 activity is adequately and consistently suppressed by aspirin in stroke patients, this effect is not reliably indicated by whole-blood clotting in response to AA. These data help to explain why the reported prevalence of aspirin resistance in stroke from studies employing AA-induced platelet reactivity is high and cast doubt on the veracity of such reports.
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2013 Category: Neurology Authors: Nalyaka Sambu, Ashwin Radhakrishnan, Nicola Englyst, Nicolas Weir, Nick Curzen Tags: Original Articles Source Type: research

Infections Present on Admission Compared with Hospital-Acquired Infections in Acute Ischemic Stroke Patients
Background: To date, few studies have assessed the influence of infections present on admission (POA) compared with hospital-acquired infections (HAIs) on neurologic deterioration (ND) and other outcome measures in acute ischemic stroke (AIS).Methods: Patients admitted with AIS to our stroke center (July 2010 to December 2010) were retrospectively assessed. The following infections were assessed: urinary tract infection, pneumonia, and bacteremia. Additional chart review was performed to determine whether the infection was POA or HAI. We assessed the relationship between infections in ischemic stroke patients and several o...
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Amelia K. Boehme, Andre D. Kumar, Adrianne M. Dorsey, James E. Siegler, Monica S. Aswani, Michael J. Lyerly, Dominique J. Monlezun, Alexander J. George, Karen C. Albright, Timothy M. Beasley, Sheryl Martin-Schild Tags: Original Articles Source Type: research

Response to “Geotopographic and Environmental Characteristics of Communities and the Seasonality of Stroke Occurrences” (published in J Stroke Cerebrovasc Dis, Volume 22, issue 3, 2013, 279-280)
I appreciate Dr. Turin’s interest in our article. Analysis of regional differences in the incidence of stroke, even within Japan, is complicated, because many factors may influence the conclusions, including regional differences of pollutants, temperature, lifestyle factors (such as salt, smoking, and alcohol consumption levels), and the distribution of facilities (urban or rural areas) contributing data to the Japanese Standard Stroke Registry Study (JSSRS). Turin et al pointed out the regional difference in pollutants related to motorized vehicles in Japan. In the 1990s, Japan’s environmental legislation was tighten...
Source: Journal of Stroke and Cerebrovascular Diseases - December 16, 2011 Category: Neurology Authors: Shunya Takizawa Tags: Letter to the Editor Source Type: research