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Source: The American Journal of Cardiology
Education: Study
Procedure: Angioplasty
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Total 45 results found since Jan 2013.
Risk of Stroke in Patients With High On-Clopidogrel Platelet Reactivity to Adenosine Diphosphate After Percutaneous Coronary Intervention
In conclusion, in patients with coronary artery disease undergoing PCI, the presence of HPR to adenosine diphosphate is a risk factor for stroke.
Source: The American Journal of Cardiology - March 17, 2014 Category: Cardiology Authors: Nevio Taglieri, Maria Letizia Bacchi Reggiani, Tullio Palmerini, Gabriele Ghetti, Francesco Saia, Pamela Gallo, Carolina Moretti, Gianni Dall'Ara, Cinzia Marrozzini, Antonio Marzocchi, Claudio Rapezzi Tags: Coronary Artery Disease Source Type: research
Percutaneous Coronary Intervention as a Trigger for Stroke
This study aimed to quantify the transient change in risk of stroke for up to 12 weeks after PCI. We applied the case-crossover method, using data from the Norwegian Patient Register on all hospitalizations in Norway in the period of 2008 through 2014. The relative risk (RR) of ischemic stroke was highest during the first two days after PCI (RR 17.5, 95% CI 4.2-72.8), and decreased gradually during the following weeks.
Source: The American Journal of Cardiology - September 28, 2016 Category: Cardiology Authors: Torunn Varmdal, Imre Janszky, Inger Johanne Bakken, Hanne Ellekj ær, Hild Fjærtoft, Siri Eldevik Håberg, Kaare Harald Bønaa Source Type: research
Stroke Risk Stratification With the CHADS2 Score in Patients Without Atrial Fibrillation Who Underwent Percutaneous Coronary Intervention
The clinical significance of the CHADS2 score remains unclear in patients with coronary artery disease (CAD) without atrial fibrillation (AF). Therefore, the purpose of this study was to evaluate the association between the CHADS2 score and the long-term risk of ischemic stroke and its severity in patients with CAD with and without AF. Using the CREDO (Coronary Revascularization Demonstrating Outcome study)-Kyoto Registry Cohort-3, the present study population consisted of 11,516 patients with CAD who underwent percutaneous coronary intervention without oral anticoagulants at discharge.
Source: The American Journal of Cardiology - August 13, 2022 Category: Cardiology Authors: Yuki Obayashi, Hiroki Shiomi, Takeshi Morimoto, Yodo Tamaki, Moriaki Inoko, Ryusuke Nishikawa, Kazuhisa Kaneda, Ko Yamamoto, Yasuaki Takeji, Akihiro Komasa, Kyohei Yamaji, Satoshi Shizuta, Tomohisa Tada, Kazuya Nagao, Satoru Suwa, Toshihiro Tamura, Hiroki Source Type: research
Comparison of In-Hospital Outcomes With Low-Dose Fibrinolytic Therapy Followed by Urgent Percutaneous Coronary Intervention Versus Percutaneous Coronary Intervention Alone for Treatment of ST-Elevation Myocardial Infarction
In patients with acute ST-elevation myocardial infarction (STEMI), a strategy of prehospital reduced dose fibrinolytic administration coupled with urgent percutaneous coronary intervention (PCI), termed FAST-PCI strategy, has been found to be superior to primary PCI (PPCI) alone. A coordinated STEMI system of care that includes FAST-PCI should offer better outcomes than a system in which prehospital diagnosis of STEMI is followed by PPCI alone. The aim of this study was to compare the in-hospital outcomes for patients treated with the FAST-PCI approach with outcomes for patients treated with the PPCI approach in a common s...
Source: The American Journal of Cardiology - March 14, 2013 Category: Cardiology Authors: Neel S. Bhatt, Amirreza Solhpour, Prakash Balan, Armin Barekatain, James J. McCarthy, Stefano Sdringola, Ali E. Denktas, Richard W. Smalling, H. Vernon Anderson Tags: Coronary Artery Disease Source Type: research
Unanswered Questions in Patients With Concurrent Atrial Fibrillation and Acute Coronary Syndrome
In conclusion, until the results of additional ongoing or planned randomized trials are known, clinicians must continue to rely on expert opinion and their own clinical judgment when treating these patients.
Source: The American Journal of Cardiology - December 16, 2013 Category: Cardiology Authors: Daniel S. Ice, Timothy A. Shapiro, Eric M. Gnall, Peter R. Kowey Tags: Review Source Type: research
Usefulness and Safety of Vorapaxar in Patients With Non–ST-Segment Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention (from the TRACER Trial)
In conclusion, among patients with PCI, the effect of vorapaxar is consistent with the overall TRACER results. Patients who received a BMS underwent shorter courses of clopidogrel therapy and displayed trends toward greater ischemic benefit from vorapaxar and lesser bleeding risk, compared with patients who received a DES.
Source: The American Journal of Cardiology - June 20, 2014 Category: Cardiology Authors: Marco Valgimigli, Pierluigi Tricoci, Zhen Huang, Philip E. Aylward, Paul W. Armstrong, Frans Van de Werf, Sergio Leonardi, Harvey D. White, Petr Widimsky, Robert A. Harrington, Angel Cequier, Edmond Chen, Yuliya Lokhnygina, Lars Wallentin, John Strony, Ke Tags: Coronary Artery Disease Source Type: research
Meta-Analysis of Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting in Left Main Coronary Arterial Disease
Despite the increase in use of percutaneous coronary intervention (PCI) in left main (LM) coronary disease, its efficacy compared with coronary artery bypass grafting (CABG) is unclear. We performed a meta-analysis of randomized controlled trials to assess the optimal revascularization strategy. Our search yielded 8 studies reporting relevant outcomes which were pooled using the inverse-variance method, and the hazard ratio (HR) was calculated. The primary outcome was all-cause mortality, myocardial infarction (MI), or stroke (MACE), and the secondary outcome was death/MI/stroke/repeat revascularization (expanded MACE).
Source: The American Journal of Cardiology - March 28, 2017 Category: Cardiology Authors: Abdur R. Khan, Harsh Golwala, Avnish Tripathi, Haris Riaz, Arnav Kumar, Michael P. Flaherty, Deepak L. Bhatt Source Type: research
Comparison of Procedural Success and Long-Term Outcomes of Stent Thrombosis in Coronary Bypass Grafts Versus Native Coronary Arteries
Percutaneous coronary intervention within bypass grafts accounts for a significant percentage of total interventions. Bypass graft interventions are associated with an increased risk for stent thrombosis (ST), a condition that leads to significant morbidity and mortality. Despite this, the procedural characteristics and long-term outcomes of patients with bypass-graft ST have not been reported. The aim of the present study was to evaluate the procedural success and long-term outcomes of patients presenting with ST of coronary bypass grafts. Clinical and procedural characteristics of 205 ST cases at 5 academic hospitals wer...
Source: The American Journal of Cardiology - December 20, 2012 Category: Cardiology Authors: Stephen W. Waldo, Ehrin J. Armstrong, Khung Keong Yeo, Ehtisham Mahmud, Mitul Patel, Ryan Reeves, John S. MacGregor, Reginald I. Low, Jason H. Rogers, Kendrick A. Shunk Tags: Coronary Artery Disease Source Type: research
Alice in Wonderland of Drug-Eluting Stent for Unprotected Left Main Disease
We read the recent meta-analysis by Jang et al of 3 randomized trials and 9 observational studies (with 5,079 patients) comparing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) versus coronary artery bypass grafting (CABG) for unprotected left main coronary artery (ULMCA) disease. At 1-year follow-up, there were trends toward lower risk for death (odds ratio [OR] 0.68, 95% confidence interval [CI] 0.45 to 1.02, p = 0.06) and the composite end point of death, myocardial infarction, or stroke (OR 0.70, 95% CI 0.49 to 1.00, p = 0.05) in the DES group compared to the CABG group. However, target vess...
Source: The American Journal of Cardiology - March 15, 2013 Category: Cardiology Authors: Hisato Takagi, Takuya Umemoto Tags: Readers' Comments Source Type: research
Effect of Transcatheter (via Femoral Artery) Aortic Valve Implantation on the Platelet Count and Its Consequences
In conclusion, a decrease in platelet count is a common phenomenon after TAVI, and its severity is associated with poor outcomes.
Source: The American Journal of Cardiology - March 25, 2013 Category: Cardiology Authors: Romain Gallet, Aurelien Seemann, Masanori Yamamoto, Delphine Hayat, Gauthier Mouillet, Jean-Luc Monin, Pascal Gueret, Jean-Paul Couetil, Jean-Luc Dubois-Randé, Emmanuel Teiger, Pascal Lim Tags: Valvular Heart Disease Source Type: research
Development and Validation of a Cardiovascular Risk Assessment Model in Patients With Established Coronary Artery Disease
In conclusion, in patients with established coronary artery disease, the risk of cardiovascular mortality during longer term follow-up can be adequately predicted using the clinical characteristics available at baseline. However, the prediction of nonfatal outcomes, both separately and combined with fatal outcomes, poses major challenges for clinicians and model developers.
Source: The American Journal of Cardiology - April 3, 2013 Category: Cardiology Authors: Linda Battes, Rogier Barendse, Ewout W. Steyerberg, Maarten L. Simoons, Jaap W. Deckers, Daan Nieboer, Michel Bertrand, Roberto Ferrari, Willem J. Remme, Kim Fox, Johanna J.M. Takkenberg, Eric Boersma, Isabella Kardys Tags: Coronary Artery Disease Source Type: research
Comparison by Meta-Analysis of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With a Mean Age of ≥70 Years
A paucity of published data evaluating the outcomes of older patients (age ≥70 years) undergoing revascularization for unprotected left main coronary artery disease is available. We performed aggregate data meta-analyses of the clinical outcomes (all-cause mortality, nonfatal myocardial infarction, stroke, repeat revascularization, and major adverse cardiac and cerebrovascular events at 30 days and 12 and 22 months) in studies comparing percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in patients with a mean age of ≥70 years and unprotected left main coronary artery disease. A compre...
Source: The American Journal of Cardiology - May 31, 2013 Category: Cardiology Authors: Mahboob Alam, Salim S. Virani, Saima A. Shahzad, Sahar Siddiqui, Khaleeq H. Siddiqui, Shahzad A. Mumtaz, Neal S. Kleiman, Joseph S. Coselli, Nasser M. Lakkis, Hani Jneid Tags: Coronary Artery Disease Source Type: research
Incidence and Outcome of High On-Treatment Platelet Reactivity in Patients With Non-ST Elevation Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention (from the VIP VerifyNow and Inhibition of Platelet Reactivity Study)
In conclusion, 1/3 of patients with acute coronary syndromes who underwent percutaneous coronary intervention and stenting showed high on-treatment RPR on bedside monitoring. They had a worse prognosis, but the level of platelet inhibition was not independently associated with the incidence of ischemic or bleeding events.
Source: The American Journal of Cardiology - June 7, 2013 Category: Cardiology Authors: Francesco Saia, Massimiliano Marino, Gianluca Campo, Marco Valgimigli, Paolo Guastaroba, Nevio Taglieri, Stefano Tondi, Antonio Manari, Vincenzo Guiducci, Pietro Sangiorgio, Elisabetta Varani, Paolo Magnavacchi, Rossana De Palma, Antonio Marzocchi Tags: Coronary Artery Disease Source Type: research
Race/Ethnic Disparities in Risk Factor Control and Survival in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial
This study sought to evaluate the impact of race/ethnicity on cardiovascular risk factor control and on clinical outcomes in a setting of comparable access to medical care. The BARI 2D trial enrolled 1,750 participants from the United States and Canada that self-reported either White non-Hispanic (n = 1,189), Black non-Hispanic (n = 349), or Hispanic (n = 212) race/ethnicity. Participants had type 2 diabetes and coronary artery disease and were randomized to cardiac and glycemic treatment strategies. All patients received intensive target-based medical treatment for cardiac risk factors. Average follow-up was 5.3 years....
Source: The American Journal of Cardiology - August 5, 2013 Category: Cardiology Authors: Nirat Beohar, Veronica V. Sansing, Andrew M. Davis, V.S. Srinivas, Tarek Helmy, Andrew D. Althouse, Stephen B. Thomas, Maria Mori Brooks, BARI 2D Study Group Tags: Coronary Artery Disease Source Type: research
