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Source: The American Journal of Cardiology
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Total 366 results found since Jan 2013.
Chronotropic Response to Exercise Testing and the Risk of Stroke
Although the chronotropic response to exercise testing, defined as an inadequate heart rate response to incremental exercise to volitional fatigue, is associated with adverse cardiovascular outcomes, it remains unclear whether this response is related to the future risk of cerebrovascular events. We tested the hypothesis that the chronotropic response to exercise is associated with an increased risk of stroke in a general population. This prospective study was based on a population sample of 2,036 men aged 42-60 years in the Kuopio Ischemic Heart Disease cohort study.
Source: The American Journal of Cardiology - December 18, 2020 Category: Cardiology Authors: Sae Young Jae, Kevin Heffernan, Sudhir Kurl, Setor K. Kunutsor, Barry A. Franklin, Kai Savonen, Jari A. Laukkanen Source Type: research
Meta-Analysis of Implantable Loop Recorder for Atrial Fibrillation Detection in Patients With Ischemic Stroke
Atrial fibrillation (AF) is the most common arrhythmia in adults and it is responsible for about one-third of all ischemic strokes.1 Although prior studies have found more frequently detected AF following stroke with longer duration of monitoring, ambiguity remains regarding the optimal duration of ambulatory cardiac monitoring.1 Therefore, we conducted a meta-analysis of solely randomized clinical trials (RCTs) to evaluate the efficacy and safety of implantable loop recorder (ILR) in AF detection, and subsequent reduction of recurrent strokes in patients with recent ischemic strokes.
Source: The American Journal of Cardiology - November 15, 2021 Category: Cardiology Authors: Babikir Kheiri, Saket Sanghai, Hani Alhamoud, Mohammed Osman, Eric Stecker, Charles A. Henrikson, Babak Nazer Source Type: research
Relation of Abdominal Obesity to Risk of Atrial Fibrillation (From the Reasons for Geographic and Racial Differences in Stroke REGARDS Study)
Our knowledge of the association between abdominal obesity (AO) and the risk of atrial fibrillation (AF) after adjusting for body mass index (BMI) is limited. We included 11,617 Black and White participants (mean age 63.0 ± 8.4 years) from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) national cohort study who were free of AF at baseline. A multivariable logistic regression model was used to estimate the odds ratio (OR) with 95% confidence interval (CI) of incident AF associated with AO.
Source: The American Journal of Cardiology - December 11, 2021 Category: Cardiology Authors: Joonseok Kim, Pankaj Arora, Soo Y. Kwon, Vibhu Parcha, Emily B. Levitan, Byron C. Jaeger, Elsayed Z. Soliman, Virginia J. Howard Source Type: research
Relation of Hemoglobin A1C Levels to Risk of Ischemic Stroke and Mortality in Patients With Diabetes Mellitus and Atrial Fibrillation
This study aimed to assess the incidence and risks of ischemic stroke and mortality according to baseline HbA1c levels in patients with DM and AF. We conducted a cohort study using Clalit Health Services electronic medical records. The study population included all Clalit Health Services members aged ≥25 years, with the first diagnosis of AF between January 1, 2010, and December 31, 2016, who had a diagnosis of DM.
Source: The American Journal of Cardiology - March 29, 2022 Category: Cardiology Authors: Louise Kezerle, Moti Haim, Amichay Akriv, Adi Berliner Senderey, Asaf Bachrach, Maya Leventer-Roberts, Meytal Avgil Tsadok Source Type: research
Stroke Risk Stratification With the CHADS2 Score in Patients Without Atrial Fibrillation Who Underwent Percutaneous Coronary Intervention
The clinical significance of the CHADS2 score remains unclear in patients with coronary artery disease (CAD) without atrial fibrillation (AF). Therefore, the purpose of this study was to evaluate the association between the CHADS2 score and the long-term risk of ischemic stroke and its severity in patients with CAD with and without AF. Using the CREDO (Coronary Revascularization Demonstrating Outcome study)-Kyoto Registry Cohort-3, the present study population consisted of 11,516 patients with CAD who underwent percutaneous coronary intervention without oral anticoagulants at discharge.
Source: The American Journal of Cardiology - August 13, 2022 Category: Cardiology Authors: Yuki Obayashi, Hiroki Shiomi, Takeshi Morimoto, Yodo Tamaki, Moriaki Inoko, Ryusuke Nishikawa, Kazuhisa Kaneda, Ko Yamamoto, Yasuaki Takeji, Akihiro Komasa, Kyohei Yamaji, Satoshi Shizuta, Tomohisa Tada, Kazuya Nagao, Satoru Suwa, Toshihiro Tamura, Hiroki Source Type: research
Comparison of Stroke and Bleeding Risk Profile in Patients With Atrial Fibrillation and Chronic Kidney Disease
This study explores the impact of glomerular filtration rate (GFR) in the embolic-hemorrhagic balance among a large cohort of patients with AF. The study cohort included 15,457 patients diagnosed with AF between January 2014 and April 2020. The risk of ischemic stroke and major bleeding was determined by competing risk regression.
Source: The American Journal of Cardiology - April 12, 2023 Category: Cardiology Authors: Jos é Antonio Parada Barcia, Sergio Raposeiras Roubin, Emad Abu-Assi, Pablo Domínguez Erquicia, Andrea Lizancos Castro, Lucía Rioboo Lestón, Juan Ocampo Míguez, Inmaculada González Bermúdez, Andrés Íñiguez-Romo Source Type: research
Effectiveness and Safety of Direct Oral Anticoagulants for Stroke Prevention in Atrial Fibrillation Patients With Extreme Obesity
Direct oral anticoagulants (DOACs) are a favored treatment to prevent stroke in patients with atrial fibrillation (AF). There are limited data concerning the efficacy and safety of DOACs in obese. Obesity leads to wide structural and physiological changes that may affect the pharmacokinetics and pharmacodynamics of drugs. The optimal dosing strategies for DOACs in this significant and growing sub-group remain unknown. The study aimed to evaluate on a large scale the safety and efficacy of DOAC treatment in extreme obese patients with AF.
Source: The American Journal of Cardiology - July 18, 2023 Category: Cardiology Authors: Boaz Elad, Nimra Maman, Snait Ayalon, Lee Hilary Goldstein Source Type: research
Overtreatment and Undertreatment With Anticoagulation in Relation to Cardioversion of Atrial Fibrillation (the RHYTHM-AF Study)
In conclusion, ECV was frequently performed under appropriate antithrombotic therapy for most high-risk patients with atrial fibrillation, whereas PCV was frequently performed without appropriate antithrombotic therapy. To enhance pericardioversion stroke prevention, cardioversion algorithms should focus less on the type of conversion and more on stroke risk factors and atrial fibrillation duration.
Source: The American Journal of Cardiology - November 11, 2013 Category: Cardiology Authors: Gregory Y.H. Lip, Anselm K. Gitt, Jean-Yves Le Heuzey, Lori D. Bash, Christopher J. Morabito, Alexandra A. Bernhardt, Christine McCrary Sisk, François Chazelle, Harry J. Crijns, RHYTHM-AF Scientific Committee Tags: Arrhythmias and Conduction Disturbances Source Type: research
Self-Reported Snoring and Risk of Cardiovascular Disease Among Postmenopausal Women (from the Women's Health Initiative)
In conclusion, snoring is associated with a modest increased risk of incident CHD, stroke, and CVD after adjustment for CVD risk factors. Additional studies are needed to elucidate the mechanisms by which snoring might be associated with CVD risk factors and outcomes.
Source: The American Journal of Cardiology - December 7, 2012 Category: Cardiology Authors: Megan Sands, Eric B. Loucks, Bing Lu, Mary A. Carskadon, Katherine Sharkey, Marcia Stefanick, Judith Ockene, Neomi Shah, Kristen G. Hairston, Jennifer Robinson, Marian Limacher, Lauren Hale, Charles B. Eaton Tags: Preventive Cardiology Source Type: research
Comparison of Intermediate-Term Outcomes of Coronary Artery Bypass Grafting Versus Drug-Eluting Stents for Patients ≥75 Years of Age
In conclusion, older patients experienced similar mortality and stroke/MI/mortality rates for CABG and PCI with DES, although repeat revascularization rates were higher for patients undergoing PCI with DES.
Source: The American Journal of Cardiology - December 16, 2013 Category: Cardiology Authors: Edward L. Hannan, Ye Zhong, Peter B. Berger, Gary Walford, Jeptha P. Curtis, Chuntao Wu, Ferdinand J. Venditti, Robert S.D. Higgins, Craig R. Smith, Stephen J. Lahey, Spencer B. King Tags: Coronary Artery Disease Source Type: research
Prognosis in Patients Hospitalized With Permanent and Nonpermanent Atrial Fibrillation in Heart Failure
In conclusion, in patients with AF and HF, the risk of admission for HF and risk of death were higher when AF was permanent, particularly in patients with preserved LVEF. Stroke risk did not differ according to the pattern of AF, whatever the LVEF.
Source: The American Journal of Cardiology - January 15, 2014 Category: Cardiology Authors: Sophie Taillandier, Anne Brunet Bernard, Benedicte Lallemand, Edouard Simeon, Lauriane Pericart, Nicolas Clementy, Dominique Babuty, Laurent Fauchier Tags: Heart Failure Source Type: research
Dabigatran in Catheter Ablation of Atrial Fibrillation: A Call for a Randomized Control Trial
We read the study by Sardar et al entitled Meta-Analysis of Risk of Stroke or Transient Ischemic Attack With Dabigatran for Atrial Fibrillation Ablation. Sardar et al have conducted a rigorous systematic review and meta-analysis on the risk of stroke and transient ischemic attack with the use of dabigatran in catheter ablation (CA) of atrial fibrillation (AF) in comparison to warfarin. They have reported higher risk of thromboembolic events (including stroke and transient ischemic attack) with the periprocedural use of dabigatran contrary to several other meta-analyses that have shown no statistically significant differ...
Source: The American Journal of Cardiology - March 28, 2014 Category: Cardiology Authors: Aref A. Bin Abdulhak, Abdur Rahman Khan, Alan P. Wimmer Tags: Readers' Comments Source Type: research
Quantitative Evaluation of Mitral Regurgitation Secondary to Mitral Valve Prolapse by Magnetic Resonance Imaging and Echocardiography
The present prospective study was designed to evaluate the accuracy of quantitative assessment of mitral regurgitant fraction (MRF) by echocardiography and cardiac magnetic resonance imaging (cMRI) in the modern era using as reference method the blinded multi-parametric integrative assessment of mitral regurgitation (MR) severity. 2D- and 3D- MRF by echocardiography (2D Echo MRF and 3D Echo MRF) were obtained by measuring the difference in left ventricular (LV) total stroke volume (obtained from either 2D or 3D acquisition) and aortic forward stroke volume normalized to LV total stroke volume.
Source: The American Journal of Cardiology - August 14, 2015 Category: Cardiology Authors: Caroline Le Goffic, Manuel Toledano, Pierre-Vladimir Ennezat, Camille Binda, Anne-Laure Castel, François Delelis, Pierre Graux, Christophe Tribouilloy, Sylvestre Maréchaux Source Type: research
Effects of Oral Anticoagulant Therapy in Medical Inpatients ≥65 Years With Atrial Fibrillation
In this retrospective cohort observational study, we investigated mortality, ischemic, and hemorrhagic events in patients ≥65 years with atrial fibrillation consecutively discharged from an Acute Geriatric Ward in the period 2010 to 2013. Stroke and bleeding risk were evaluated using CHA2DS2-VASC (congestive heart failure/left ventricular dysfunction, hypertension, aged ≥75 years, diabetes mellitus, stroke/transient ischemic attack/systemic embolism, vascular disease, aged 65 to 74 years, gender category) and HAS-BLED (hypertension, abnormal renal/liver function, stroke, bleeding history or predisposition, labile in...
Source: The American Journal of Cardiology - December 1, 2015 Category: Cardiology Authors: Mario Bo, Irene Sciarrillo, Federica Li Puma, Marco Badinella Martini, Yolanda Falcone, Marina Iacovino, Enrica Grisoglio, Elena Menditto, Gianfranco Fonte, Enrico Brunetti, Guido Maggiani, Giovanni Carlo Isaia, Fiorenzo Gaita Tags: Arrhythmias and Conduction Disturbances Source Type: research
Gender Differences of Thromboembolic Events in Atrial Fibrillation
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia and increases the risk of thromboembolism and stroke; however, these risks are not the same for women and men. This review examines the evidence and clinical significance of increased thromboembolic risk in women with AF. The balance of results from over thirty recent studies suggests that female gender is an independent stroke risk factor in AF, and the inclusion of female gender in stroke risk stratification models, such as CHA2DS2-VASc, has improved risk assessment.
Source: The American Journal of Cardiology - December 31, 2015 Category: Cardiology Authors: Emily Y. Cheng, Melissa H. Kong Source Type: research
