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Exosomes and their miRNA/protein profile in keratoconus-derived corneal stromal cells
Exp Eye Res. 2023 Sep 13:109642. doi: 10.1016/j.exer.2023.109642. Online ahead of print.ABSTRACTKeratoconus (KC) is a corneal thinning disorder and a leading cause of corneal transplantation worldwide. Exosomes are small, secreted extracellular vesicles (30-150 nm) that mediate cellular communication via their proteins, lipids, and nucleic acid content. We aimed to characterize the exosomes secreted by primary corneal fibroblasts from subjects with or without KC. Using human keratoconus stromal fibroblast cells (HKC, n = 4) and healthy stromal fibroblasts (HCF, n = 4), we collected and isolated exosomes using serial ultrac...
Source: Experimental Eye Research - September 15, 2023 Category: Opthalmology Authors: Rachel Hadvina Mariam Lotfy Khaled Theresa Akoto Wenbo Zhi Dimitrios Karamichos Yutao Liu Source Type: research

Ineffective esophageal motility is associated with acute rejection after lung transplantation independent of gastroesophageal reflux
CONCLUSION: Pre-transplant IEM was associated with acute rejection after transplantation, even after controlling for acid and nonacid reflux. Esophageal motility testing may be considered in lung transplant to predict outcomes.PMID:37377592 | PMC:PMC10292138 | DOI:10.3748/wjg.v29.i21.3292
Source: World Journal of Gastroenterology - June 28, 2023 Category: Gastroenterology Authors: Wai-Kit Lo Brent Hiramoto Hilary J Goldberg Nirmal Sharma Walter W Chan Source Type: research

Inclusion of Exercise Prescription in Solid Organ Transplant in Physical Therapy Curricula Across Canadian Universities: A National Survey
Conclusions: SOT exercise prescription is not extensively covered in PT curricula and does not include all organ groups to the same extent. Students have few practical opportunities, which are important to gain the abilities and confidence to treat this population. The development of a continuing education course could promote greater knowledge.PMID:37325206 | PMC:PMC10262824 | DOI:10.3138/ptc-2020-0118
Source: Physiotherapy Canada - June 16, 2023 Category: Physiotherapy Authors: Koty Negreanu Zhi Qi Wang Julia Campanelli Amanda Zappia Daniela Massierer Jadranka Spahija Tania Janaudis-Ferreira Source Type: research

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