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The importance of selected markers of inflammation and blood-brain barrier damage for short-term ischemic stroke prognosis.
Authors: Lasek-Bal A, Jedrzejowska-Szypulka H, Student S, Warsz-Wianecka A, Zareba K, Puz P, Bal W, Pawletko K, Lewin-Kowalik J Abstract Acute cerebral ischemia triggers local and systemic immune response. The aims of this project was to assess the blood serum concentration of the markers of inflammation and markers of the blood brain barrier damage on the first day of ischemic stroke, and the mutual correlations between these marker levels. Patients with first-in-life stroke were analysed according to: plasma concentration of the following markers on the first day of stroke: interleukin 2 (IL-2) and interleuki 6 (...
Source: Journal of Physiology and Pharmacology - July 31, 2019 Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research

Relevance of admission hyperglycaemia and diabetes mellitus to efficacy and safety of mechanical thrombectomy in stroke patients
CONCLUSIONS: Diabetes mellitus has a neutral effect on the angiographic and clinical outcomes of mechanical thrombectomy in stroke patients. It does not increase the risk of intracranial haemorrhage after instrumental therapy. It is admission hyperglycaemia, rather than diabetes mellitus, that is a predictor of poor functional status in patients treated with thrombectomy. According to our results, the patient's neurological status, age, and the outcome of thrombectomy are relevant to the functional status in the acute ischaemic stroke period.PMID:36394219 | DOI:10.5603/PJNNS.a2022.0063
Source: Neurologia i Neurochirurgia Polska - November 17, 2022 Category: Neurology Authors: Anetta Lasek-Bal Amadeusz Żak Łukasz Binek Sebastian Student Aleksandra Cie ślik Wies ław Bal Wiktor Rybicki Jolanta Kulawik-Szwajca Source Type: research