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Specialty: Cardiology
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Total 67 results found since Jan 2013.
Sympathetic Nervous System and Atherosclerosis
Int J Mol Sci. 2023 Aug 23;24(17):13132. doi: 10.3390/ijms241713132.ABSTRACTAtherosclerosis is characterized by the narrowing of the arterial lumen due to subendothelial lipid accumulation, with hypercholesterolemia being a major risk factor. Despite the recent advances in effective lipid-lowering therapies, atherosclerosis remains the leading cause of mortality globally, highlighting the need for additional therapeutic strategies. Accumulating evidence suggests that the sympathetic nervous system plays an important role in atherosclerosis. In this article, we reviewed the sympathetic innervation in the vasculature, norepi...
Source: Atherosclerosis - September 9, 2023 Category: Cardiology Authors: Yutang Wang Jack Anesi Michelle C Maier Mark A Myers Ernesto Oqueli Christopher G Sobey Grant R Drummond Kate M Denton Source Type: research
2023 Vascular Research Initiatives Conference: Structural and Immune Cells in Vascular Disease
JVS Vasc Sci. 2023 Jul 10;4:100117. doi: 10.1016/j.jvssci.2023.100117. eCollection 2023.ABSTRACTThe 2023 Vascular Research Initiatives Conference (VRIC) was held in Boston, Massachusetts, and coincided with the first day of Vascular Discovery 2023, hosted by the American Heart Association. VRIC attracts vascular clinicians, surgeon-scientists, and basic science researchers to a common arena to facilitate the exchange of basic and translational science to stimulate and inspire participants to study and find solutions to vascular conditions. The theme of the conference this year was "Structural and Immune Cells in Vascular D...
Source: Atherosclerosis - August 31, 2023 Category: Cardiology Authors: Carly Thaxton Katherine Gallagher Alan Dardik Source Type: research
Trends in Cannabis Use, Blood Pressure and Hypertension in Middle-Aged Adults: Findings from NHANES, 2009-2018, Corroon, et al
CONCLUSIONS: A history of monthly cannabis use for more than one year was not independently associated with either increased blood pressure or prevalent hypertension in a nationally representative sample of middle-aged US adults.PMID:37479221 | DOI:10.1093/ajh/hpad068
Source: American Journal of Hypertension - July 21, 2023 Category: Cardiology Authors: Jamie Corroon Igor Grant Ryan Bradley Matthew A Allison Source Type: research
Inclisiran: A New Strategy for LDL-C Lowering and Prevention of Atherosclerotic Cardiovascular Disease
Vasc Health Risk Manag. 2023 Jul 6;19:421-431. doi: 10.2147/VHRM.S338424. eCollection 2023.ABSTRACTMultiple lines of evidence confirm that the cumulative burden of low-density lipoprotein cholesterol (LDL-C) is causally related to the development of atherosclerotic cardiovascular disease (ASCVD). As such, lowering LDL-C is a central tenet in all ASCVD prevention guidelines, which recommend matching the intensity of LDL-C lowering with the absolute risk of the patient. Unfortunately, issues such as difficulty with long-term adherence to statin therapy and inability to achieve desired LDL-C thresholds with statins alone resu...
Source: Atherosclerosis - July 12, 2023 Category: Cardiology Authors: Michael S Albosta Jelani K Grant Pam Taub Roger S Blumenthal Seth S Martin Erin D Michos Source Type: research
The past, present and future of sleep medicine in China
Beijing Da Xue Xue Bao Yi Xue Ban. 2023 Jun 18;55(3):567. doi: 10.19723/j.issn.1671-167X.2023.03.027.ABSTRACTSleep is a highly conserved phenomenon in endotherms, and has a universal physiological function across all species. In mammals, sleep can be divided into two stages: rapid eye movement (REM) sleep and non-REM (NREM) sleep, which alternate in a cyclic manner. Humans spend about one-third of their lives asleep. Sufficient sleep is necessary for humans to sustain everyday functioning. Sleep plays an important role in regulating energy metabolism, immune defense, endocrine function, and the consolidation of memory proc...
Source: Atherosclerosis - June 29, 2023 Category: Cardiology Authors: J H Deng X L Huang X X Liu J Sun L Lu Source Type: research
Investigation of Combined Carotid Endarterectomy and Coronary Artery Bypass Graft Surgery Outcomes and Adverse Event Risk Factors in the Vascular Quality Initiative
CONCLUSIONS: Combined CEA and CABG provides excellent long-term mortality prevention in patients with co-existing severe coronary and carotid atherosclerosis. Simultaneous CEA and CABG provides equivalent stroke prevention and long-term survival to both a cohort of patients undergoing coronary revascularization within 5 years of CEA and patients undergoing isolated CEA or CABG in the literature. The two most impactful modifiable risk factors towards long-term stroke and mortality prevention for patients undergoing simultaneous CEA-CABG are patch placement at CEA site and adherence to statin medication therapy.PMID:37303074...
Source: Atherosclerosis - June 11, 2023 Category: Cardiology Authors: Ashley Penton Jonathan Lin Grant Kolde Matthew DeJong Matthew Blecha Source Type: research
Sensitive magnetic particle imaging of haemoglobin degradation for the detection and monitoring of intraplaque haemorrhage in atherosclerosis
EBioMedicine. 2023 Mar 9;90:104509. doi: 10.1016/j.ebiom.2023.104509. Online ahead of print.ABSTRACTBACKGROUND: Intraplaque haemorrhage (IPH) drives atherosclerosis progression and is a key imaging biomarker of unstable plaques. Non-invasive and sensitive monitoring of IPH is challenging due to the compositional complexity and dynamic nature of atherosclerotic plaques. Magnetic particle imaging (MPI) is a highly sensitive, radiation-free, and no-tissue-background tomographic technique that detects superparamagnetic nanoparticles. Thus, we aimed to investigate whether MPI can in vivo detect and monitor IPH.METHODS: Thirty h...
Source: Atherosclerosis - March 11, 2023 Category: Cardiology Authors: Wei Tong Yingqian Zhang Hui Hui Xin Feng Bin Ning Tengfei Yu Wei Wang Yaxin Shang Guanghao Zhang Suhui Zhang Feng Tian Wen He Yundai Chen Jie Tian Source Type: research
Association between proteomic biomarkers and myocardial fibrosis measured by MRI: the multi-ethnic study of atherosclerosis
EBioMedicine. 2023 Feb 27;90:104490. doi: 10.1016/j.ebiom.2023.104490. Online ahead of print.ABSTRACTBACKGROUND: Cardiac magnetic resonance imaging (CMR) determines the extent of interstitial fibrosis, measured by increased extracellular volume (ECV), and replacement fibrosis with late gadolinium myocardial enhancement (LGE). Despite advances in detection, the pathophysiology of subclinical myocardial fibrosis is incompletely understood. Targeted proteomic discovery technologies enable quantification of low abundance circulating proteins to elucidate cardiac fibrosis mechanisms.METHODS: Using a cross-sectional design, we s...
Source: Atherosclerosis - March 1, 2023 Category: Cardiology Authors: Hooman Bakhshi Sam A Michelhaugh Scott A Bruce Stephen L Seliger Xiaoxiao Qian Bharath Ambale Venkatesh Vinithra Varadarajan Pramita Bagchi Joao A C Lima Christopher deFilippi Source Type: research
A multiple comorbidities mouse lung infection model in < em > ApoE < /em > ‑deficient mice
Biomed Rep. 2023 Feb 6;18(3):21. doi: 10.3892/br.2023.1603. eCollection 2023 Mar.ABSTRACTAcute pneumonia is characterised by a period of intense inflammation. Inflammation is now considered to be a key step in atherosclerosis progression. In addition, pre-existing atherosclerotic inflammation is considered to play a role in pneumonia progression and risk. In the present study, a multiple comorbidities murine model was used to study respiratory and systemic inflammation that results from pneumonia in the setting of atherosclerosis. Firstly, a minimal infectious dose of Streptococcus pneumoniae (TIGR4 strain) to produce clin...
Source: Atherosclerosis - February 27, 2023 Category: Cardiology Authors: Benjamin Bartlett Silvia Lee Herbert P Ludewick Teck Siew Shipra Verma Grant Waterer Vicente F Corrales-Medina Girish Dwivedi Source Type: research
