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P134/298 Endovascular therapy delay for acute large vessel occlusions is associated with worse functional outcome and increased mortality - Quantified
ConclusionShorter times to puncture and reperfusion impact mRS and mortality in LVO stroke patients. Adequate hospital protocols and education may lead to faster and more efficient stroke activations leading to a shorter time to MT and reperfusion. Goals of door-to-puncture must be established in order to achieve better outcome.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Carrion-Penagos, J., Morsi, R. Z., Kothari, S., Desai, H., Tarabichi, A., Thind, S., Coleman, E., Brorson, J. R., Mendelson, S. J., Prabhakaran, S., Mansour, A., Hout, T. K. Tags: 2.1 ISCHEMIC - Logistics Source Type: research

P151/175 Direct aspiration with EMBOVAC - first clinical experience and clot composition (results the "PERFECT study)
ConclusionThis is the first clinical evaluation of EMBOVAC. Direct aspiration with EMBOVAC as first line therapy resulted in high rates of reperfusion and favorable clinical outcomes. Clot composition analysis can aid in better understanding of the stroke etiology and means for effective clot removal.Disclosure of InterestAcandis (OJ, CL, JF); Microvention (GM, CC, JF); Stryker (GM, CC, JF); Medtronic (GM, CC, JF); Surge2surgery (BG); MIVI (CC); Phenox (CL, JF); Penumbra (CL, JF); GSK (AS); German Ministry of Science & Education and Economy & Innovation, EU, Hamburgische Investitions-/Förderbank, Philips, B...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Lobotesis, K., Jansen, O., Marnat, G., Gory, B., Nordmeyer, H., Eckert, B., Alessandro, P., Cognard, C., Loehr, C., Bracco, S., Schaefer, A., Macera, A., Fiehler, J., Doyle, K., Piano, M. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

E-110 Bilateral hypoplasia of the internal carotid artery (ICA) and intracranial vasculopathy with 'moyamoya phenomenon in association with alagille syndrome
ConclusionThe educational value of our case lies not only in the rarity of the condition but also in the uniqueness of patient presentation. It would be a helpful addition to the existing literature on rare genetic syndromes with cerebral vasculature involvement.Abstract E-110 Figure 1Disclosures H. Shakeel: None. J. Gandhi: None. R. Singh: None. A. Graziano: None. R. Cerejo: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Shakeel, H., Gandhi, J., Singh, R., Graziano, A., Cerejo, R. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-161 Transradial arterial access for neurointervention: the basics, benefits, and tools
Transradial access (TRA) is a feasible method for interventional neurovascular procedures, gaining popularity after becoming the standard access route in cardiovascular interventions. While advantages of TRA include better safety, cost reduction, and patient experience, barriers include a narrow variety of dedicated equipment for radial to neurovascular target vessels, need for further training for physicians and fellows, and physician bias toward Transfemoral access (TFA) due to training and familiarity.This educational poster focuses on the general technical details of TRA, including discussion of the TRA and distal TRA ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kelly, C., Abbas, M., Harris, D., Abbas, M., Luqman, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

P-001 Residual in-stent carotid stenosis and cigarette smoking are predictors of restenosis after stenting (CAS)
ConclusionWe present the largest single-center data in the US to date on carotid artery stenosis treated with CAS, and factors associated with restenosis. Residual in-stent carotid stenosis and smoking history were independent predictors. Maximizing treatment of initial stenosis within stent for carefully selected patients and aggressive smoking cessation education are important steps in preventing future carotid restenosis.Abstract P-001 Figure 1Carotid restenosis after carotid arty tenting (%) by categories of degree of residual stenosis after initial procedure (a), and by cutpoint of 29% (b)Disclosures P. Lai: None. K. ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Lai, P., Snyder, K., Baig, A., Khawar, W., Donnelly, B., Siddiqi, M., Kruk, M., Jacoby, W., Davies, J., Siddiqui, A., Levy, E. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

O20 Thrombectomy for medium vessel occlusions: treatment effect of successful recanalization on long term functional outcome
ConclusionTICI 2b recanalization in MeVO increased probability of good outcome from 27% to 58%, TICI 3 recanalization did not further improve prognosis. Do you have any conflict of interest to declare?: YesConflict of Interest StatementHelge Kniep and Fabian Flottmann are consultants for Eppdata.Milani Deb-Chatterji has received research grants from the Werner Otto Stiftung.Götz Thomalla received fees as consultant from Acandis, Bayer, and Portola, and fees as lecturer from Acandis, Alexion, Amarin, Bayer, Boehringer-Ingelheim, BristolMyersSquibb, Daiichii Sankyo, Portola, and Stryker.Jens Fiehler received research...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Bechstein, M., Broocks, G., Brekenfeld, C., Flottmann, F., Deb-Chatterji, M., Meyer, L., Hanning, U., Thomalla, G., Fiehler, J., Gellissen, S. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P46 How much of the improvement in functional outcome after successful recanalization is explained by follow-up infarct volume reduction?
Conclusions57% of the improvement of functional outcome after successful recanalization is explained by follow-up infarct volume reduction. Results reflect established pathophysiological assumptions and confirm the value of infarct volume as imaging endpoint in clinical trials.ReferencesBoers AMM, Jansen IGH, Brown S, et al. Mediation of the relationship between endovascular therapy and functional outcome by follow-up infarct volume in patients with acute ischemic stroke. Jama Neurology 2019;76:194–202. DOI: 10.1001/Jamaneurol.2018.3661 Do you have any conflict of interest to declare?: YesConflict of Interest Stateme...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Bechstein, M., Broocks, G., Austein, F., Brekenfeld, C., Flottmann, F., Deb-Chatterji, M., Thomalla, G., Hanning, U., Fiehler, J., Gellissen, S. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P83 The relationship of functional outcome after mechanical thrombectomy and serum glucose is partially mediated by edema formation
ConclusionEdema formation explains 15% of the total adverse effects of high blood glucose levels. Major pathways might include other direct effects of high blood glucose, such as altered vessel wall and thrombus characteristics and higher thrombogenicity of the cerebral blood flow.ReferencesThorén, M., et al. "Predictors for Cerebral Edema in Acute Ischemic Stroke Treated with Intravenous Thrombolysis." Stroke 2017;48(9): 2464–2471. Do you have any conflict of interest to declare?: YesConflict of Interest StatementHelge Kniep is a consultant for Eppdata.Jens Fiehler received research support from: German Minis...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Bechstein, M., Hanning, U., Fiehler, J., Broocks, G. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

206 Stroke and sociodemographic factors: a review
Discussion Certain areas within stroke medicine are well researched, with cause and effect relationships established. However, there are certain protected patient characteristics with minimal/no evidence which require further research to ensure equal access for all patients to stroke care.
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 12, 2022 Category: Neurosurgery Authors: Vidot, M., Wu, K., Mitchell, J., Nitkunan, A., Carr, G. Tags: Poster presentations Source Type: research

Inpatient virtual shared medical appointments to improve health literacy, increase patient self-efficacy, and reduce provider burnout in acute cerebrovascular pathology patients and their caregivers: a pilot study
CONCLUSIONS: Implementation of a vSMA program at a tertiary care center during a pandemic was feasible. Themes caregivers expressed on the postsession survey included better understanding of caring for a stroke patient and coping with the unpredictability of a patient's prognosis. The pandemic has precipitated shifts toward telehealth, but this study highlights the importance of avoiding marginalization of elderly and less technologically inclined populations.PMID:35921191 | DOI:10.3171/2022.4.FOCUS21764
Source: Neurosurgical Focus - August 3, 2022 Category: Neurosurgery Authors: Uma V Mahajan Neha Sharma Marquis Maynard Lei Kang Collin M Labak Alankrita Raghavan Martha Sajatovic Alan Hoffer Berje H Shammassian James M Wright Xiaofei Zhou Christina Huang Wright Source Type: research

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