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Herpes Simplex Virus and Varicella Zoster Virus Infections in Cancer Patients
Viruses. 2023 Feb 5;15(2):439. doi: 10.3390/v15020439.ABSTRACTHerpes simplex virus (HSV) and varicella zoster virus (VZV) are alpha herpesviruses that establish life-long latent infection in neuronal ganglia after primary infection. Periodic reactivation of these viruses results in recurrent infections that can have significant impact on patients' quality of life. HSV commonly causes oral and genital mucocutaneous infections whereas VZV is responsible for varicella/chickenpox and herpes zoster/shingles, but cancer patients are at particularly higher risk of complications including disseminated and visceral infections due t...
Source: Herpes - February 28, 2023 Category: Infectious Diseases Authors: Ralph Tayyar Dora Ho Source Type: research

Herpes zoster ophthalmicus after COVID-19 vaccine booster in healthy younger adult: a case report
Clin Exp Vaccine Res. 2023 Jan;12(1):82-84. doi: 10.7774/cevr.2023.12.1.82. Epub 2023 Jan 31.ABSTRACTThere were growing reports of herpes zoster reactivation after the coronavirus disease 2019 (COVID-19) vaccination, including a more severe form, herpes zoster ophthalmicus (HZO). A 35-year-old male presented HZO in his left V1 dermatome 10 days after his COVID-19 vaccine booster with Moderna (messenger RNA-1273). He had no history of chronic disease, immunocompromised, autoimmune, malignancy, or long-term immunosuppressive drug use. The rash improved without any further complications after being treated with oral valacyclo...
Source: Herpes - February 27, 2023 Category: Infectious Diseases Authors: Zamrud Wilda Nuril Awaly Source Type: research

Herpes Zoster after mRNA COVID-19 Vaccination: A Case Series
We present seven immunocompetent patients devoid of any comorbidities and risk factors, who developed for the first time in their life varicella-zoster virus (VZV) reactivation shortly after 1st (four patients) and 2nd dose (three patients) of mRNA COVID-19 vaccines.All four patients who exhibited herpes zoster after the 1st dose of vaccine received the 2nd dose without any adverse reactions or complications. Oral treatment prescribed to all patients with valacyclovir (Valtrex 1 mg tds/day) for 5-7 days led to a complete resolution of symptoms, and rashes disappeared within 9-14 days. Presently, All patients have completed...
Source: Skinmed - August 17, 2022 Category: Dermatology Authors: Alexandra Monastirli Efstathia Pasmatzi George Badavanis Gianna Panagiotopoulou Assimina Apostolidou Dionysios Tsambaos Source Type: research

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