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Interactions of Betel Quid Constituents with Drug Disposition Pathways: An Overview
Curr Drug Metab. 2023 Feb 28. doi: 10.2174/1389200224666230228142052. Online ahead of print.ABSTRACTGlobal estimates indicate that over 600 million individuals worldwide consume the areca (betel) nut in some form. Nonetheless, its consumption is associated with a myriad of oral and systemic ailments, such as pre-cancerous oral lesions, oropharyngeal cancers, liver toxicity and hepatic carcinoma, cardiovascular distress, and addiction. Users commonly chew sliver nuts in a complex consumable preparation called betel quid (BQ). Consequently, the user is exposed to a wide array of chemicals with diverse pharmacokinetic behavio...
Source: Current Drug Metabolism - February 28, 2023 Category: Drugs & Pharmacology Authors: Jasmine Canlas Alan L Myers Source Type: research
Electronic cigarettes and health outcomes: umbrella and systematic review of the global evidence
CONCLUSION: E-cigarettes can be harmful to health, particularly for non-smokers and children, adolescents, and young adults. Their effects on many important health outcomes are uncertain. E-cigarettes may be beneficial for smokers who use them to completely and promptly quit smoking, but they are not currently approved smoking cessation aids. Better quality evidence is needed regarding the health impact of e-cigarette use, their safety and efficacy for smoking cessation, and effective regulation.REGISTRATION: Systematic review: PROSPERO, CRD42020200673 (prospective).PMID:36939271 | DOI:10.5694/mja2.51890
Source: Med J Aust - March 20, 2023 Category: General Medicine Authors: Emily Banks Amelia Yazidjoglou Sinan Brown Mai Nguyen Melonie Martin Katie Beckwith Amanda Daluwatta Sai Campbell Grace Joshy Source Type: research
Interactions of Betel Quid Constituents with Drug Disposition Pathways: An Overview
Curr Drug Metab. 2023 Feb 28. doi: 10.2174/1389200224666230228142052. Online ahead of print.ABSTRACTGlobal estimates indicate that over 600 million individuals worldwide consume the areca (betel) nut in some form. Nonetheless, its consumption is associated with a myriad of oral and systemic ailments, such as pre-cancerous oral lesions, oropharyngeal cancers, liver toxicity and hepatic carcinoma, cardiovascular distress, and addiction. Users commonly chew sliver nuts in a complex consumable preparation called betel quid (BQ). Consequently, the user is exposed to a wide array of chemicals with diverse pharmacokinetic behavio...
Source: Current Drug Metabolism - February 28, 2023 Category: Drugs & Pharmacology Authors: Jasmine Canlas Alan L Myers Source Type: research
Electronic cigarettes and health outcomes: umbrella and systematic review of the global evidence
CONCLUSION: E-cigarettes can be harmful to health, particularly for non-smokers and children, adolescents, and young adults. Their effects on many important health outcomes are uncertain. E-cigarettes may be beneficial for smokers who use them to completely and promptly quit smoking, but they are not currently approved smoking cessation aids. Better quality evidence is needed regarding the health impact of e-cigarette use, their safety and efficacy for smoking cessation, and effective regulation.REGISTRATION: Systematic review: PROSPERO, CRD42020200673 (prospective).PMID:36939271 | DOI:10.5694/mja2.51890
Source: Med J Aust - March 20, 2023 Category: General Medicine Authors: Emily Banks Amelia Yazidjoglou Sinan Brown Mai Nguyen Melonie Martin Katie Beckwith Amanda Daluwatta Sai Campbell Grace Joshy Source Type: research
