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Drug: Magnesium
Management: Food and Drug Administration (FDA)

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Total 29 results found since Jan 2013.

Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level for Magnesium Supplementation in Adults
Adv Nutr. 2023 Jul 11:S2161-8313(23)01335-2. doi: 10.1016/j.advnut.2023.06.008. Online ahead of print.ABSTRACTIn 1997, the US Institute of Medicine (IOM) dietary reference intakes (DRI) Committee established a magnesium (Mg) tolerable upper intake level (UL) for adults of 350 mg/d from supplemental intake alone. Diarrhea was the limiting factor. The safety of oral Mg dietary supplements exceeding the UL is currently in debate. Increasing the UL may result in more Mg supplementation, decreasing the prevalence of undernutrition for this nutrient and thus providing additional protection against numerous chronic diseases. This...
Source: Adv Data - July 24, 2023 Category: Epidemiology Authors: Rebecca Costello Andrea Rosanoff Forrest Nielsen Christina West Source Type: research

Review of benefits and adverse effects of the most commonly used local anesthetic adjuvants in peripheral nerve blocks
J Physiol Pharmacol. 2022 Jun;73(3). doi: 10.26402/jpp.2022.3.02. Epub 2022 Oct 22.ABSTRACTRecently, peripheral nerve blocks are extensively applied for many patients undergoing surgical or nonsurgical analgesia. However, the effectiveness is limited by the duration of action of local anesthetics. Therefore, the application of adding local anesthetic adjuvants is evolved to prolong the duration of analgesia and decrease the concentration of local anesthetics in peripheral nerve blocks. There are many local anesthetic adjuvants available such as morphine, fentanyl, sufentanil, hydromorphone, and buprenorphine, dexmedetomidi...
Source: J Physiol Pharmacol - October 27, 2022 Category: Drugs & Pharmacology Authors: J Yang J-W Zhang Source Type: research