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Mechanistic Insight into the role of Vitamin D and Zinc in Modulating Immunity Against COVID-19: A View from an Immunological Standpoint
Biol Trace Elem Res. 2023 Mar 9:1-15. doi: 10.1007/s12011-023-03620-4. Online ahead of print.ABSTRACTThe pathophysiology of coronavirus disease-19 (COVID-19) is characterized by worsened inflammation because of weakened immunity, causing the infiltration of immune cells, followed by necrosis. Consequently, these pathophysiological changes may lead to a life-threatening decline in perfusion due to hyperplasia of the lungs, instigating severe pneumonia, and causing fatalities. Additionally, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause mortality due to viral septic shock, resulting from unr...
Source: Biological Trace Element Research - March 8, 2023 Category: Biology Authors: Nuzhat Ahsan Mohammad Imran Yousuf Mohammed Fatme Al Anouti Mohammad Idreesh Khan Tanushree Banerjee Mohd Adnan Fauzia Ashfaq Marek Kieliszek Syed Amir Ashraf Afrozul Haq Source Type: research

A potential protective role of magnesium in neuroCOVID
Magnes Res. 2022 Jan 1;35(1):18-26. doi: 10.1684/mrh.2022.0497.ABSTRACTSeveral recent studies support a role of dysregulated magnesium homeostasis in COVID-19. In the present narrative review, we focus on the neurological aspects of this disease, collectively known as neuroCOVID, and we propose some mechanisms by which alterations of magnesium may contribute to the involvement of the nervous system in the context of SARS-CoV-2 infection. Further fundamental, translational, and clinical research is needed to underpin the potential relationships between altered magnesium status and neuro-COVID, with potentially novel therape...
Source: Magnesium Research - October 10, 2022 Category: Biochemistry Authors: Valentina Cenacchi Jeanette A Maier Maria Paola Perini Source Type: research

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