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Antiviral, immunomodulatory, and neuroprotective effect of lithium
J Integr Neurosci. 2022 Mar 23;21(2):68. doi: 10.31083/j.jin2102068.ABSTRACTCurrently, in psychiatry, lithium is a drug of choice as a mood stabilizer in the maintenance treatment of bipolar disorder for the prevention of manic and depressive recurrences. The second most important psychiatric use of lithium is probably increasing the efficacy of antidepressants in treatment-resistant depression. In addition to its mood-stabilizing properties, lithium exerts antisuicidal, antiviral, immunomodulatory, and neuroprotective effects. The goal of the review is to describe the experimental and clinical studies on the last three pr...
Source: Journal of Integrative Neuroscience - April 1, 2022 Category: Neuroscience Authors: Janusz K Rybakowski Source Type: research

Lithium salts as a treatment for COVID-19: Pre-clinical outcomes
CONCLUSIONS: These results provide pre-clinical evidence of the antiviral and immunotherapeutic effects of lithium against SARS-CoV-2, which supports an advance to clinical trials on COVID-19's patients.PMID:35364381 | PMC:PMC8947939 | DOI:10.1016/j.biopha.2022.112872
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 1, 2022 Category: Drugs & Pharmacology Authors: O Soriano-Torres E Noa Romero N L Gonz ález Sosa J M Enr íquez Puertas A Fragas Quintero M Garc ía Montero D Mart ín Alfonso Y Infante Hern ández M Lastre L Rodr íguez-Pérez Y Borrego V E Gonz ález I G Vega R Ramos Pupo L M Reyes M T Zumeta Dub é Source Type: research

Antiviral, immunomodulatory, and neuroprotective effect of lithium
J Integr Neurosci. 2022 Mar 23;21(2):68. doi: 10.31083/j.jin2102068.ABSTRACTCurrently, in psychiatry, lithium is a drug of choice as a mood stabilizer in the maintenance treatment of bipolar disorder for the prevention of manic and depressive recurrences. The second most important psychiatric use of lithium is probably increasing the efficacy of antidepressants in treatment-resistant depression. In addition to its mood-stabilizing properties, lithium exerts antisuicidal, antiviral, immunomodulatory, and neuroprotective effects. The goal of the review is to describe the experimental and clinical studies on the last three pr...
Source: Journal of Integrative Neuroscience - April 1, 2022 Category: Neuroscience Authors: Janusz K Rybakowski Source Type: research

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